In this episode of ACEP Frontline, we sit down with Dr. David Carlberg to discuss eosinophilic esophagitis (EoE), an increasingly recognized inflammatory condition of the esophagus that can present with food impactions, difficulty swallowing, chest discomfort, and chronic reflux-like symptoms. Dr. Carlberg breaks down the underlying causes of EoE, including the role of allergic and immune-mediated responses, while highlighting the importance of recognizing the condition in both pediatric and adult patients presenting to the emergency department. The conversation also explores diagnostic considerations and current management strategies ranging from dietary modifications and proton pump inhibitors to topical steroids and endoscopic interventions. The episode wraps with a reminder for emergency physicians to check out the ACEP POC Smart Phrase on EoE for practical bedside guidance and streamlined documentation support.Supported by Sanofi.