<description>&lt;p&gt;In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles, potential risk factors for severe disease following influenza infection before and SARS-CoV-2 circulation, before discussing if SARS-CoV-2 infection impacts sperm fertility, the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC,continues to dispel the myth of viral rebound, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, and long COVID. For more information about this body of work, For more information about this body of work, listen to &lt;a title="" href= "https://www.microbe.tv/twiv/twiv-1088/"&gt;TWiV 1088&lt;/a&gt;.&lt;/p&gt; &lt;p&gt;Subscribe (free): &lt;a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065"&gt; Apple Podcasts&lt;/a&gt;, &lt;a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D"&gt;Google Podcasts&lt;/a&gt;, &lt;a href= "http://twiv.microbeworld.libsynpro.com/twiv"&gt;RSS&lt;/a&gt;, &lt;a href="http://eepurl.com/Gcw59"&gt;email&lt;/a&gt;&lt;/p&gt; &lt;p&gt;Become a &lt;a href= "https://www.microbe.tv/contribute"&gt;patron&lt;/a&gt; of TWiV!&lt;/p&gt; &lt;h3 id="links-for-this-episode" class="wp-block-heading"&gt; &lt;strong&gt;Links for this episode&lt;/strong&gt;&lt;/h3&gt; &lt;ul&gt; &lt;li&gt;Measles &lt;a href= "https://www.cdc.gov/measles/cases-outbreaks.html"&gt;&lt;strong&gt;tracking&lt;/strong&gt;&lt;/a&gt; (CDC)&lt;/li&gt; &lt;li&gt;Influenza &lt;a href= "https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofae203/7644685?utm_source=advanceaccess&amp;utm_campaign=ofid&amp;utm_medium=email&amp;nbd=40427954633&amp;nbd_source=campaigner"&gt;&lt;strong&gt;risk factors&lt;/strong&gt;&lt;/a&gt; for potential severe outcomes (OFID)&lt;/li&gt; &lt;li&gt;COVID-19 &lt;a href= "https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html"&gt;&lt;strong&gt;national&lt;/strong&gt;&lt;/a&gt; trend (CDC)&lt;/li&gt; &lt;li&gt;Does SARS-CoV-2 infection influence &lt;a href= "https://www.nature.com/articles/s41598-024-58797-y"&gt;&lt;strong&gt;sperm quality&lt;/strong&gt;&lt;/a&gt; (Scientific Reports)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.cidrap.umn.edu/covid-19/cdc-advisers-recommend-spring-covid-booster-seniors"&gt; &lt;strong&gt;Spring COVID-19 booster&lt;/strong&gt;&lt;/a&gt; recommendations (CIDRAP)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.cdc.gov/media/releases/2024/s-0228-covid.html"&gt;&lt;strong&gt; Older adult&lt;/strong&gt;&lt;/a&gt; spring booster available (CDC)&lt;/li&gt; &lt;li&gt;Advisory committee for immunization practices&lt;a href= "https://www.cdc.gov/vaccines/acip/meetings/slides-2024-02-28-29.html"&gt;&lt;strong&gt; slides&lt;/strong&gt;&lt;/a&gt; (CDC)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-02-28-29/06-COVID-Wallace-508.pdf"&gt; &lt;strong&gt;Advisory committee for immunization practices&lt;/strong&gt;&lt;/a&gt; spring 2024 COVID-19 boosters (CDC)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-02-28-29/04-COVID-Link-Gelles-508.pdf"&gt; &lt;strong&gt;Slide 19&lt;/strong&gt;&lt;/a&gt; (CDC)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.fda.gov/news-events/press-announcements/fda-roundup-march-22-2024"&gt; &lt;strong&gt;EUA for pemgarda&lt;/strong&gt;&lt;/a&gt;&lt;strong&gt; &lt;/strong&gt;(FDA)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.cdc.gov/coronavirus/2019-ncov/your-health/quarantine-isolation.html"&gt; &lt;strong&gt;CDC Quarantine&lt;/strong&gt;&lt;/a&gt; guidelines (CDC)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.cdc.gov/mmwr/volumes/73/wr/mm7308a5.htm"&gt;&lt;strong&gt;NIH&lt;/strong&gt;&lt;/a&gt; COVID-19 treatment guidelines (NIH)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#ExecutiveSummaryandBackground"&gt; &lt;strong&gt;Infectious Disease Society guidelines&lt;/strong&gt;&lt;/a&gt; for treatment and management (IDSociety)&lt;/li&gt; &lt;li&gt;Nirmatrelvir for &lt;a href= "https://www.nejm.org/doi/full/10.1056/NEJMoa2309003"&gt;&lt;strong&gt;vaccinated or unvaccinated&lt;/strong&gt;&lt;/a&gt; COVID-19 patients (NEJM)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://journals.sagepub.com/doi/10.1177/20499361241236582"&gt;&lt;strong&gt; Nirmatrelvir/ritonavir vs. remdesivir&lt;/strong&gt;&lt;/a&gt; for treatment of high risk outpatients (Therapeutic Advances in Infectious Disease)&lt;/li&gt; &lt;li&gt;Molnupiravir &lt;a href= "https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011"&gt;&lt;strong&gt;safety&lt;/strong&gt;&lt;/a&gt; and efficacy (JMV)&lt;/li&gt; &lt;li&gt;Convalescent plasma recommendation for &lt;a href= "file:///Users/Amy/Desktop/"&gt;&lt;strong&gt;immunocompromised&lt;/strong&gt;&lt;/a&gt; (IDSociety)&lt;/li&gt; &lt;li&gt;Outpatient treatment with concomitant &lt;a href= "https://journals.asm.org/doi/10.1128/mbio.00400-24"&gt;&lt;strong&gt;vaccine-boosted convalescent plasma&lt;/strong&gt;&lt;/a&gt; (mBio)&lt;/li&gt; &lt;li&gt;Updated &lt;a href= "https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html"&gt;&lt;strong&gt;respiratory virus&lt;/strong&gt;&lt;/a&gt; guidances (CDC)&lt;/li&gt; &lt;li&gt;What do when your &lt;a href= "https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-risk-%20assesment-hcp.html"&gt;&lt;strong&gt;heathcare provider &lt;/strong&gt;&lt;/a&gt;is infected with SARS-CoV-2 (CDC)&lt;/li&gt; &lt;li&gt;Managing healthcare staffing &lt;a href= "https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html"&gt;&lt;strong&gt;shortages&lt;/strong&gt;&lt;/a&gt; (CDC)&lt;/li&gt; &lt;li&gt;Steroids,&lt;a href= "https://academic.oup.com/ofid/article/10/3/ofad105/7055978"&gt;&lt;strong&gt;dexamethasone&lt;/strong&gt;&lt;/a&gt; at the right time (OFID)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19"&gt; &lt;strong&gt;Anticoagulation&lt;/strong&gt;&lt;/a&gt;&lt;strong&gt;&lt;u&gt; &lt;/u&gt;&lt;/strong&gt;guidelines (hematology.org) Long COVID evidence based review &lt;a href= "https://www.microbe.tv/twiv/twiv-1088/"&gt;&lt;strong&gt;TWiV&lt;/strong&gt;&lt;/a&gt; shout out (TWiV 1088)&lt;/li&gt; &lt;li&gt;Contribute to our &lt;a href= "https://parasiteswithoutborders.com/"&gt;ASTMH fundraiser at PWB&lt;/a&gt;&lt;/li&gt; &lt;li&gt;&lt;a title="" href= "https://www.microbe.tv/twiv/twiv-1106-letters/"&gt;Letter&lt;/a&gt;&lt;a title="" href= "https://www.microbe.tv/twiv/twiv-1106-letters/"&gt;s&lt;/a&gt;&lt;a title="" href= "https://www.microbe.tv/twiv/twiv-1106-letters/"&gt; read&lt;/a&gt; on TWiV 1106&lt;/li&gt; &lt;li&gt;Dr. Griffin’s COVID treatment summary (&lt;a title="" href= "https://twiv.s3.amazonaws.com/COVID+treatment+summary+032224.pdf"&gt;pdf&lt;/a&gt;)&lt;/li&gt; &lt;li&gt;Timestamps by &lt;a href= "https://ramseylab.vercel.app/"&gt;Jolene&lt;/a&gt;. Thanks!&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;Intro music is by &lt;a href= "http://www.ronaldjenkees.com/"&gt;Ronald Jenkees&lt;/a&gt;&lt;/p&gt; &lt;p&gt;Send your questions for Dr. Griffin to daniel@microbe.tv&lt;/p&gt;</description>

This Week in Virology

Vincent Racaniello

TWiV 1106: Clinical update with Dr. Daniel Griffin

APR 20, 202444 MIN
This Week in Virology

TWiV 1106: Clinical update with Dr. Daniel Griffin

APR 20, 202444 MIN

Description

In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles, potential risk factors for severe disease following influenza infection before and SARS-CoV-2 circulation, before discussing if SARS-CoV-2 infection impacts sperm fertility, the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC,continues to dispel the myth of viral rebound, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, and long COVID. For more information about this body of work, For more information about this body of work, listen to TWiV 1088.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]