<description>&lt;p&gt;TWiV explains the 1953 paper by Watson &amp; Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus.&lt;/p&gt; &lt;div class="fluid-width-video-wrapper"&gt;Hosts: &lt;a title="" href="https://en.wikipedia.org/wiki/Vincent_Racaniello"&gt;Vincent Racaniello&lt;/a&gt;, &lt;a title="" href= "https://medschool.umich.edu/profile/879/katherine-spindler"&gt;Kathy Spindler&lt;/a&gt;, and &lt;a title="" href= "https://bbarkerdrew.com/"&gt;Brianne Barker&lt;/a&gt;&lt;/div&gt; &lt;p&gt;Subscribe (free): &lt;a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065"&gt; Apple Podcasts&lt;/a&gt;, &lt;a href= "http://twiv.microbeworld.libsynpro.com/twiv"&gt;RSS&lt;/a&gt;, &lt;a href="http://eepurl.com/Gcw59"&gt;email&lt;/a&gt;&lt;/p&gt; &lt;p&gt;Become a &lt;a href= "https://www.microbe.tv/contribute"&gt;patron&lt;/a&gt; of TWiV!&lt;/p&gt; &lt;h3 id="links-for-this-episode" class="wp-block-heading"&gt;Links for this episode&lt;/h3&gt; &lt;ul class="wp-block-list"&gt; &lt;li&gt;&lt;a title="" href="https://www.microbe.tv/contribute"&gt;Support science education &lt;/a&gt;at MicrobeTV&lt;/li&gt; &lt;li&gt;Immune 100 &lt;a title="" href= "https://www.eventbrite.com/e/immune-100-live-in-nyc-tickets-1797664816859?aff=oddtdtcreator"&gt;live at the Incubator&lt;/a&gt;&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.npr.org/sections/shots-health-news/2025/11/20/nx-s1-5615040/cdc-rfk-childhood-vaccines-autism"&gt; CDC revives debunked 'link' between childhood vaccines and autism&lt;/a&gt; (npr)&lt;/li&gt; &lt;li&gt;A structure for deoxyribose nucleic acid (Nature &lt;a title= "" href= "https://www.mskcc.org/teaser/1953-nature-papers-watson-crick-wilkins-franklin.pdf"&gt;pdf&lt;/a&gt;)&lt;/li&gt; &lt;li&gt;&lt;a href= "https://www.atsjournals.org/doi/full/10.1164/rccm.2302011"&gt;Three Papers, Three Lessons&lt;/a&gt; (Am J Resp Crit Care Med)&lt;/li&gt; &lt;li&gt;Discovery of &lt;a title="" href= "https://profiles.nlm.nih.gov/spotlight/sc/feature/doublehelix"&gt;Double Helix&lt;/a&gt; (Crick Papers)&lt;/li&gt; &lt;li&gt;Jim Watson was &lt;a title="" href= "https://www.nytimes.com/2025/11/16/opinion/james-watson-dna.html?unlocked_article_code=1.2k8.VzXR.gxeSwp-B8_Yp&amp;smid=nytcore-ios-share&amp;referringSource=articleShare"&gt;blinded by DNA&lt;/a&gt; (NY Times)&lt;/li&gt; &lt;li&gt;What &lt;a title="" href= "https://www.nature.com/articles/d41586-023-01313-5"&gt;Rosalind Franklin contributed&lt;/a&gt; (Nature)&lt;/li&gt; &lt;li&gt;EBV reprograms &lt;a title="" href= "https://pubmed.ncbi.nlm.nih.gov/41223250/"&gt;autoreactive B-cells in lupus&lt;/a&gt; (Sci Transl Med)&lt;/li&gt; &lt;li&gt;EBV and the &lt;a title="" href= "https://www.science.org/doi/10.1126/scitranslmed.aec0501"&gt;making of lupus&lt;/a&gt; (Sci Transl Med)&lt;/li&gt; &lt;li&gt;Timestamps by &lt;a href= "https://ramseylab.vercel.app/"&gt;Jolene&lt;/a&gt; Ramsey. Thanks!&lt;/li&gt; &lt;/ul&gt; &lt;h3 class="wp-block-heading"&gt;Weekly Picks&lt;/h3&gt; &lt;p&gt;&lt;strong&gt;Brianne&lt;/strong&gt; – &lt;a href= "https://cvr-engagement.co.uk/virus-snowflakes"&gt;Virus snowflakes&lt;/a&gt;&lt;br /&gt; &lt;strong&gt;Kathy&lt;/strong&gt; – &lt;a href= "https://www.youtube.com/watch?v=yvY61ArnxPg&amp;list=PLkCzlk8e8aNfPZoSgvp6m-aRmY4lsUbD6&amp;index=3&amp;pp=iAQB"&gt;When "Physic(k)s Lost Its 'k' and other Language Quarks&lt;/a&gt;&lt;br /&gt; &lt;strong&gt;Vincent&lt;/strong&gt; – &lt;a href= "https://en.wikipedia.org/wiki/The_Peripheral"&gt;The Peripheral &lt;/a&gt;by William Gibson&lt;/p&gt; &lt;p&gt;Intro music is by &lt;a href= "http://www.ronaldjenkees.com/"&gt;Ronald Jenkees&lt;/a&gt;&lt;/p&gt; &lt;p&gt;Send your virology questions and comments to twiv@microbe.tv&lt;/p&gt; &lt;p&gt;Content in this podcast should not be construed as medical advice.&lt;/p&gt;</description>

This Week in Virology

Vincent Racaniello

TWiV 1273: EBV and lupus have not escaped our notice

NOV 23, 202597 MIN
This Week in Virology

TWiV 1273: EBV and lupus have not escaped our notice

NOV 23, 202597 MIN

Description

TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus.

Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode Weekly Picks

Brianne – Virus snowflakes Kathy – When "Physic(k)s Lost Its 'k' and other Language Quarks Vincent – The Peripheral by William Gibson

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.