#68 Phylogenetic inference from raw reads and Read2Tree with David Dylus

AUG 28, 202349 MIN
the bioinformatics chat

#68 Phylogenetic inference from raw reads and Read2Tree with David Dylus

AUG 28, 202349 MIN

Description

<p>In this episode, <a href="https://www.unil.ch/dee/en/home/menuguid/people/previous-collaborators/dr-david-dylus.html">David Dylus</a> talks about <a href="https://github.com/DessimozLab/read2tree">Read2Tree</a>, a tool that builds alignment matrices and phylogenetic trees from raw sequencing reads. By leveraging the database of orthologous genes called <a href="https://omabrowser.org/oma/home/">OMA</a>, Read2Tree bypasses traditional, time-consuming steps such as genome assembly, annotation and all-versus-all sequence comparisons.</p> <p>Links:</p> <ul> <li><a href="https://www.nature.com/articles/s41587-023-01753-4">Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree</a> (David Dylus, Adrian Altenhoff, Sina Majidian, Fritz J. Sedlazeck, Christophe Dessimoz)</li> <li><a href="https://ecoevocommunity.nature.com/posts/read2tree-infers-phylogenetic-trees-from-raw-sequencing-reads-quick-and-easy">Background story</a></li> <li><a href="https://github.com/DessimozLab/read2tree">Read2Tree on GitHub</a></li> <li><a href="https://omabrowser.org/oma/home/">OMA browser</a></li> <li><a href="https://www.theguardian.com/news/audio/2023/jul/31/the-novelist-who-became-a-war-crimes-investigator-victoria-amelina-podcast">The Guardian’s podcast about Victoria Amelina and Volodymyr Vakulenko</a></li> </ul> <p>If you enjoyed this episode, please consider supporting the podcast on <a href="https://www.patreon.com/bioinfochat">Patreon</a>.</p>