Join Andy Cumpstey and Kate Leslie in this broadcast from the ANESTHESIOLOGY® 2025 meeting. They welcome guests Stacie G. Deiner, an anesthesiologist, professor and vice-chair for research at Dartmouth Hitchcock Medical Center and Mark D. Neuman, anesthesiologist and Horatio C. Wood Professor of Anesthesiology at the Perelman School of Medicine at the University of Pennsylvania. We discuss the new ASA guidelines for older adults. The episode delves into the development, significant recommendations, and implementation of these guidelines, emphasizing the importance of preoperative evaluation and the choice of anesthesia technique. Mark and Stacie also highlight ongoing research and the future of perioperative care for older adults. This conversation underscores the role of shared decision-making and proactive health measures in improving surgical outcomes. The ASA guideline can be found here: https://www.asahq.org/standards-and-practice-parameters/practice-advisory-perioperative-care-of-older-adults-scheduled-for-inpatient-surgery The REGAIN study can be found here: https://www.nejm.org/doi/full/10.1056/NEJMoa2113514