Siim Land Podcast

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:15 Zone 2 cardio01:44 Napping03:03 Walking05:09 Polyphasic sleeping06:47 Mouth breathing07:52 Soleus pushups09:40 Stretching11:10 Mobility12:03 Yoga13:20 HIIT14:20 Sprinting14:48 Plyometrics16:12 Morning sunlight17:05 Evening sunset17:52 Blocking out blue light19:12 Red light therapy20:37 Infrared light21:43 Supplements23:30 Education25:20 Problem solving26:14 Weight lifting26:56 Bilingualism27:10 Sunbathing28:54 Tanning beds30:06 Coffee and teas31:28 Low carb diet33:26 Low fat high carb diet34:04 Vegan diet34:36 Vegetarian diet35:00 Carnivore diet37:07 Paleo diet37:45 Calisthenics39:15 Mediterranean diet40:20 Sugar diet40:58 Hydration41:42 Smoking42:00 Alcohol43:40 Vaping44:00 Mouth tobacco44:35 Hyperbaric oxygen therapy (HBOT)45:40 Sauna47:09 Total plasma exchange47:53 Meditation48:49 Religion50:10 Purpose51:30 Mindfulness52:14 Intermittent fasting53:15 Low calorie diet55:40 If it fits your macros diet57:30 Pet ownership58:57 Marriage01:00:57 Ice bath01:01:57 Having children01:03:29 Social health01:04:23 Having fun and play01:04:40 Mental health01:05:03 Extended fasting01:07:07 Forest bathing01:08:02 Fasting mimicking diet01:09:10 Juice fasting01:09:41 Dry fasting01:11:16 Protein restriction01:12:17 Hot baths01:13:40 Time-restricted eating01:14:10 Circadian mismatch01:14:50 Sleep consistency01:15:23 Chronic stress01:16:00 Junk food01:16:25 Water filtration01:16:50 Air filtration01:17:00 Outdoor pollution01:17:20 Sitting lifestyle01:17:43 Sleep 7-8 hours01:18:09 Regular bloodtests01:18:40 Continuous glucose monitoring01:19:19 Exercise snacks01:19:57 Standing workdesk01:20:53 Nasal breathing01:21:03 Breathing exercises01:21:38 Recreational drugs and weed01:22:26 Peptides01:23:30 HRT & TRT01:27:04 Sleep 4-6 hours01:27:28 Stem cell therapy01:28:17 Team sports01:28:40 Steroid cycle01:29:10 Grounding01:29:32 Mouth taping01:29:51 Artificial sweeteners01:31:30 Hypochondria01:33:50 OverviewMy 2025 supplement list guide: https://www.siimland.co/supplement-list-2025100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyiGet to top 1% health: https://youtu.be/8M9uHhFf26cStart rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 What level of sports performance is unhealthy04:15 How much protein is bad for aging and longevity11:45 Bon Charge sponsorship12:45 Do I want to reach the longevity escape velocity16:40 Absorbing supplements through the skin18:40 Optimal level of testosterone for longevity22:50 Should you cycle supplements on and off27:26 How I managed to follow a healthy lifestyle in my 20s31:07 How much red light therapy can you do per day33:10 Role of stress in longevity39:35 What to do against smog and air pollution43:50 Training fast twitch muscle fibers instead of lifting weights48:30 My all out supplement stack100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Jon Berner, MD PhD is a board certified Psychiatrist from Seattle with 27 years of experience. He's also published several scientific papers.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Why Dr Berner became interested in lithium04:50 Lithium’s benefits in Alzheimer’s and dementia10:50 Lithium’s effects on mTOR and autophagy12:50 Bon Charge sponsorship13:40 Clinical evidence for lithium in dementia18:20 What’s the optimal dose for lithium26:25 Lithium for bipolar and hyperactive brains29:25 Lithium as potential treatment in neurodegeneration31:55 Lithium’s effects on kidneys34:20 Personal experience with taking lithium40:40 Is it safe to take lithium prophalactically over the counter47:55 Rapamycin synergy with lithium51:45 AI and human developmentDr Berner's practice: https://www.woodinvillepsychiatric.com/100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandYip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen, China. They're developing pharmaceuticals for extending human lifespan. We discuss their first senolytic called PCC1. Timestamps:00:00 Intro00:15 Articles about a pill making people live to 15002:50 What is PCC1 and how is it made07:10 How much can targeting senescence extend lifespan12:25 Bon Charge sponsorship13:15 Dose of PCC1 for senolytic and senomorphic effects18:30 PCC1 extending lifespan in mice by 9.4%23:20 Absorption rate of PCC1 and other senolytics27:10 Senolytics for young vs old age31:10 Human study on PCC134:40 What’s the optimal dose for senolytics38:05 Biomarkers of cell senescence40:10 Senolytic benefits on skin and retina46:35 What’s going on in Chinese longevity science52:10 Future direction of PCC1PCC1 studies: https://lonvibio.com/pages/science

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandBrady Holmer is a science writer and researcher with a Master's degree in Human Performance from the University of FloridaTimestamps:00:00 Intro00:40 Why heat acclimation has performance benefits08:10 How to train heat acclimation12:40 Bon Charge sponsorship13:30 Benefits of the sauna for fitness18:25 Saunas and injury recovery22:30 Cold exposure and exercise performance26:45 Cooling down during and before exercise31:40 How often to train heat acclimation and sauna37:05 Sauna and HRV38:10 How long to stay in the sauna41:15 Electrolytes and dehydration acclimation46:25 Differences between men and women in heat acclimation47:00 Does heat acclimation have longevity benefits49:05 Does cold exposure have longevity benefits54:30 Which research should be done more on heat acclimationFirst podcast with Brady about VO2 max: https://youtu.be/xLDaFhN6h8IBrady Holmer Twitter: https://x.com/B_HolmerBrady Holmer website: https://www.bradyholmer.com/Start rewinding your biological clock: https://www.siimland.co/course