<description>&lt;div class="OutlineElement Ltr SCXW185339977 BCX0"&gt; &lt;p class="Paragraph SCXW185339977 BCX0"&gt;&lt;span class= "TextRun SCXW185339977 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;We're resharing an episode from October 2022. How are habits – both good and bad – formed in the brain, and what role do habits play in diseases of the brain? These are some of the questions &lt;/span&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;neuroscientist&lt;/span&gt;&lt;span class="NormalTextRun SCXW185339977 BCX0"&gt;,&lt;/span&gt; &lt;span class="NormalTextRun SCXW185339977 BCX0"&gt;Talia Lerner&lt;/span&gt;&lt;span class="NormalTextRun SCXW185339977 BCX0"&gt;, PhD,&lt;/span&gt; &lt;span class="NormalTextRun SCXW185339977 BCX0"&gt;is investigating in her lab&lt;/span&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;.&lt;/span&gt; &lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;Her recent study, published in&lt;/span&gt;&lt;/span&gt; &lt;a class="Hyperlink SCXW185339977 BCX0" href= "https://news.feinberg.northwestern.edu/2022/08/24/investigating-the-role-of-dopamine-circuits-in-habit-formation/" target="_blank" rel="noreferrer noopener"&gt;&lt;span class= "TextRun Underlined SCXW185339977 BCX0" lang="EN-US" xml:lang= "EN-US" data-contrast="none"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0" data-ccp-charstyle= "Hyperlink"&gt;Cell Reports&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&lt;span class= "TextRun SCXW185339977 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;, may change the overall understanding of how habits are formed and could be broken&lt;/span&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;.  &lt;/span&gt;&lt;/span&gt;&lt;span class="EOP SCXW185339977 BCX0" data-ccp-props="{}"&gt; &lt;/span&gt;&lt;/p&gt; &lt;/div&gt; &lt;div class="OutlineElement Ltr SCXW185339977 BCX0"&gt; &lt;p class="Paragraph SCXW185339977 BCX0"&gt;&lt;span class= "TextRun SCXW185339977 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;Since this episode was first recorded in fall 2022, Lerner's team has&lt;/span&gt; &lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;published new research looking at sex differences. In a paper in&lt;/span&gt;&lt;/span&gt; &lt;a class= "Hyperlink SCXW185339977 BCX0" href= "https://news.feinberg.northwestern.edu/2023/03/23/sex-specific-mechanisms-for-major-depressive-disorder-identified-in-response-to-dysregulated-stress-hormones/" target="_blank" rel="noreferrer noopener"&gt;&lt;span class= "TextRun Underlined SCXW185339977 BCX0" lang="EN-US" xml:lang= "EN-US" data-contrast="none"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0" data-ccp-charstyle= "Hyperlink"&gt;Neuropsychopharmacology&lt;/span&gt;&lt;/span&gt;&lt;/a&gt;&lt;span class= "TextRun SCXW185339977 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;,&lt;/span&gt;&lt;/span&gt; &lt;span class= "TextRun SCXW185339977 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"&gt;&lt;span class= "NormalTextRun SCXW185339977 BCX0"&gt;her team discovered how novel sex-specific mechanisms control how stress hormones impact dopamine transmission and motivation.&lt;/span&gt;&lt;/span&gt;&lt;span class= "EOP SCXW185339977 BCX0" data-ccp-props="{}"&gt; &lt;/span&gt;&lt;/p&gt; &lt;/div&gt;</description>

Breakthroughs

Northwestern University Feinberg School of Medicine

Rewind: The Role of Dopamine in Habit Formation and Compulsive Behavior with Talia Lerner, PhD

AUG 25, 202522 MIN
Breakthroughs

Rewind: The Role of Dopamine in Habit Formation and Compulsive Behavior with Talia Lerner, PhD

AUG 25, 202522 MIN

Description

We're resharing an episode from October 2022. How are habits – both good and bad – formed in the brain, and what role do habits play in diseases of the brain? These are some of the questions neuroscientist, Talia Lerner, PhD, is investigating in her lab. Her recent study, published in Cell Reports, may change the overall understanding of how habits are formed and could be broken. Since this episode was first recorded in fall 2022, Lerner's team has published new research looking at sex differences. In a paper in Neuropsychopharmacology, her team discovered how novel sex-specific mechanisms control how stress hormones impact dopamine transmission and motivation.