<p>In this episode, I break down a 2025 paper published in Scientific Reports titled “The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer’s disease” by Liu and colleagues. <br>Over a 60-month observational period, researchers explored how two well-studied dietary patterns—the Mediterranean diet and the MIND diet—relate to changes in cognitive performance, and whether these relationships differ based on APOE-ε4 status.<br>I unpack what each diet actually emphasizes, what APOE-ε4 means for brain health, and how nutrition recommendations were personalized for carriers versus non-carriers. You’ll hear how omega-3 fatty acids, polyphenols, and antioxidant-rich foods may provide added value for people genetically at higher risk of cognitive decline.<br>Finally, I dig into the reported beta-coefficients linking both diets with cognitive trajectories on the MoCA and MMSE, highlighting how even modest long-term dietary differences can translate into meaningful brain-health outcomes.<br>Reference: Liu X, Yang B, Liu Q, Gao M, Luo M. The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer&#39;s disease. Sci Rep. 2025 Sep 24;15(1):32725. doi: 10.1038/s41598-025-17055-5.</p><p>---------</p><p>💡 Have a question you’d like me to cover on the podcast? Or interested in joining as a guest? Looking for a speaker for your event, workshop, or conference? Send me a message at ⁠⁠[email protected]⁠⁠.</p><p>🌱 Want to explore 1:1 nutrition therapy?Learn more here: <a href="https://www.foodandmoodnutritiontherapy.com/" target="_blank" rel="ugc noopener noreferrer">⁠⁠foodandmoodnutritiontherapy.com⁠⁠</a>.</p><p>🧠 Stay up to date on the latest nutrition research for brain and mental health. Subscribe to the Brain Food Digest: <a href="https://brainfooddigest.beehiiv.com/" target="_blank" rel="ugc noopener noreferrer">⁠⁠brainfooddigest.beehiiv.com⁠⁠</a>.</p>