MCAT Basics (from MedSchoolCoach)
MCAT Basics (from MedSchoolCoach)

MCAT Basics (from MedSchoolCoach)

MedSchoolCoach

Overview
Episodes

Details

Join us as we detail MCAT exam topics. Each podcast covers several MCAT sections with lessons based on review material put out by the AAMC, such as practice tests and question banks. Sam also interviews MCAT tutors and experts who share tips on how premed students can raise their score to get into medical school.

Recent Episodes

Separation and Purification Techniques
NOV 26, 2025
Separation and Purification Techniques

This episode of MCAT Basics covers several separation and purification techniques you may see on the MCAT. We’ll cover these techniques in three distinct categories: small molecules, proteins, and cells. 

Within the small molecule category, we’ll discuss extraction, crystallization and recrystallization, and chromatography (TLC and HPLC).

For proteins, we cover SDS-page, precipitation, soelectric focusing, and chromatography variations. Lastly, we’ll explain, within the world of cells, centrifugation, flow cytometry, and microfluidics. 

 

Visit MedSchoolCoach.com for more help with the MCAT. 

 

Jump into the conversation:

[00:00] MCAT Tutorig from MedSchoolCoach

[00:34] Welcome to MCAT Basics

[01:07] Topics covered in this episode

[02:24] Techniques for small molecules - extraction, crystallization and recrystallization, and chromatography (TLC and HPLC)

[28:24] Techniques for proteins - SDS-page, precipitation, isoelectric focusing, and chromatography variations

[54:47] Techniques for cells - centrifugation, flow cytometry, and microfluidics. 

 

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63 MIN
Innate Immune System
NOV 21, 2025
Innate Immune System

The immune system is split up into two main categories - the adaptive immune system and the innate immune system. 

This episode will cover the intricacies of the innate immune system beginning with an overview of its constituent cells. We will then explore three pivotal elements of the system: anatomical barriers, the general inflammatory response, and the complement system. This will show up in the bio/biochem section of the MCAT.

For additional reading on this topic, you can refer to the NIH’s Innate Immune System paper.

Visit MedSchoolCoach.com for more help with the MCAT.

 

Jump into the conversation:

[00:00] MCAT Tutoring from MedSchoolCoach

[00:34] Welcome to MCAT Basics

[01:06] Topics covered in this episode

[02:09] The goal of the innate immune system

[04:57] The cells that make up the innate immune system

[11:47] Anatomical barriers to the innate immune system

[19:53] General inflammatory response of the innate immune system

[42:49] Complement system

[45:33] MCAT Advice of the day - take as much time as you need to study for the MCAT

 

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47 MIN
Adaptive Immune System
NOV 19, 2025
Adaptive Immune System

To continue our discussion on the immune system, in this episode, we will cover the second type of immune system – the adaptive immune system. 

 

We start with covering some vocabulary that you’ll need to know to understand the immune system, then we move into the cells that make up the adaptive immune system. Then we break down the two branches of the adaptive immune system -  humoral immunity including the discussion of B cells and cell-mediated immunity highlighting T cells.  

Don’t miss our previous episode on the other type of immune system, the innate immune system. 

 

Visit MedSchoolCoach.com for more help with the MCAT.

 

Jump into the conversation:

[00:00] MCAT Tutoring from MedSchoolCoach

[00:34] Welcome to MCAT Basics

[01:06] Topics covered in this episode

[02:01] Review on the difference between innate vs. adaptive immue system

[02:32] General Vocabulary terms for the adaptive immune system

[07:05] The cells that make up the adaptive immune system

[13:09] The humoral immune system and B cells

[26:07] Cell mediated immunity and T Cells

[34:38] Antigen activation

 

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42 MIN
Renal Physiology
NOV 13, 2025
Renal Physiology

Understanding the kidneys' role in the body’s balance is essential for the MCAT and beyond.

In this episode, host Sam Smith discusses renal physiology, covering everything from kidney anatomy to the nephron’s critical functions in filtration, reabsorption, secretion, and excretion. You’ll explore the roles of the renal cortex and medulla, learn about the loop of Henle, and uncover the importance of ions, plasma volume, and pH regulation in kidney function. Plus, we’ll examine hormones like ADH and aldosterone and their impact on fluid balance, as well as essential measurements like glomerular filtration rate (GFR) for assessing kidney health.

Visit MedSchoolCoach.com for more help with the MCAT. 

Jump into the conversation:

(00:00) Intro to renal physiology

(02:43) Kidney anatomy overview

(08:38) Nephron structure and function

(09:50) Six key functions of the kidney

(12:03) Nephron Processes: Filtration

(17:32) Nephron Processes: Reabsorption and secretion

(22:51) The Loop of Henle

(26:05) Understanding osmolarity in the Loop of Henle

(26:55) Ion transport in the ascending limb

(32:04) The role of the collecting duct

(37:18) Hormonal regulation of the nephron

(46:50) Key measurements of renal function

(50:15) MCAT Advice of the Day

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52 MIN