Artist Roc Upchurch was arrested for domestic assault during the book’s initial run. You can learn a bit more about that here and here.
Upchurch and Wiebe did eventually come back for a Rat Queens finale. All published Rat Queens stories (including the “never-to-be-reprinted” issue 16) are collected in the Rat Queens Omnibus, which has a stupid tentacle cover because of course it does. It’s like the creators didn’t even read their own book.
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