<description>&lt;p class="MsoNoSpacing"&gt;&lt;span style= "font-size: 11.0pt; mso-fareast-font-family: Calibri; mso-bidi-font-family: Calibri; color: black; mso-themecolor: text1;"&gt; Advancements in clinical data and research have shown the immunotherapeutic potential of bispecific antibodies as treatment for hematologic cancers and solid tumors. In this episode, CANCER BUZZ speaks with Aaron Cumpston, PharmD, pharmacy clinical specialist for bone marrow transplant and Christine Barrett, PharmD, BCOP, medical oncology clinical pharmacy specialist who discuss the challenges of care coordination and therapy and share operational best practices for the delivery of bispecific antibodies in the community setting. &lt;/span&gt;&lt;span style= "font-size: 11.0pt; mso-fareast-font-family: Calibri; mso-bidi-font-family: Calibri;"&gt;&lt;span style="mso-spacerun: yes;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="MsoNormal"&gt; &lt;/p&gt; &lt;p class="MsoNormal"&gt;&lt;span style= "font-size: 11.0pt; line-height: 116%;"&gt;“I think we’re finding these drugs to be highly effective and having high response rates and also very durable response rates in very refractory patients.”—Aaron Cumpston, PharmD, BCOP&lt;/span&gt;&lt;/p&gt; &lt;p class="MsoNormal"&gt;&lt;span style= "font-size: 11.0pt; line-height: 116%;"&gt;“I know that in community practice it can be really difficult, but there is a network of institutions out there that have taken on administering these BiTE therapies and have a lot of experience that can be very helpful for those in community practice.” —Christine Barrett, PharmD, BCOP&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt;  &lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; Aaron Cumpston, PharmD, BCOP&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class= "eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; Pharmacy Clinical Specialist – Hematologic Malignancy, Transplant, and Cellular Therapy&lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; WVU Medicine&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; WVU Cancer Institute - Mary Babb Randolph Cancer Center&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; Morgantown, WV&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "text-indent: .5in; vertical-align: baseline; margin: 0in 0in 0in .5in;"&gt; &lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt;  &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; Christine Barrett, PharmD, BCOP&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;span class= "eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; Medical Oncology Clinical Pharmacy Specialist&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; WVU Medicine&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; WVU Cancer Institute - Mary Babb Randolph Cancer Center&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;span class= "normaltextrun"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; Morgantown, WV&lt;/span&gt;&lt;/span&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="MsoNormal"&gt; &lt;/p&gt; &lt;p class="MsoNormal"&gt;&lt;span style= "font-size: 11.0pt; line-height: 116%;"&gt;This episode was developed in connection with the ACCC education program&lt;/span&gt; &lt;a href= "https://www.accc-cancer.org/home/learn/precision-medicine/treatment/bispecific-antibodies/bispecific-antibodies-in-solid-tumor"&gt; &lt;span style="font-size: 11.0pt; line-height: 116%;"&gt;Sharing Operational Insights for the Delivery of Bispecific Antibodies in Solid Tumor&lt;/span&gt;&lt;/a&gt; &lt;span style= "font-size: 11.0pt; line-height: 116%;"&gt;and is supported by Amgen.&lt;/span&gt;&lt;/p&gt; &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; line-height: 116%;"&gt;Resources:&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;a href= "https://www.accc-cancer.org/docs/projects/bispecific-antibodies/expanding-access-to-cellular-and-bispecific-therapies.pdf?sfvrsn=5b2df5bf_2" target="_blank" rel="noopener"&gt;&lt;span class= "normaltextrun"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri; color: #0563c1;"&gt; Expanding Access to Cellular and Bispecific Therapies – Considerations and Recommendations by ACCC and SITC&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt;&lt;span class="eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;a href= "https://www.accc-cancer.org/home/learn/precision-medicine/treatment/bispecific-antibodies/bispecific-antibodies-in-solid-tumor" target="_blank" rel="noopener"&gt;&lt;span class= "normaltextrun"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri; color: #0563c1;"&gt; Sharing Operational Insights for the Delivery of Bispecific Antibodies in Solid Tumor&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt;&lt;span class= "eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt; &lt;p class="paragraph" style= "margin: 0in; vertical-align: baseline;"&gt;&lt;a href= "https://www.accc-cancer.org/home/learn/precision-medicine/treatment/bispecific-antibodies/best-practices-bispecific-antibodies" target="_blank" rel="noopener"&gt;&lt;span class= "normaltextrun"&gt;&lt;strong&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri; color: #0563c1;"&gt; Best Practices in Expanding Access to Bispecific Antibodies and Adverse Event Management&lt;/span&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt;&lt;span class= "eop"&gt;&lt;span style= "font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri;"&gt; &lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</description>

CANCER BUZZ

Association of Cancer Care Centers

Navigating the Operational Challenges of Treatment with Bispecific Antibodies

MAR 28, 202410 MIN
CANCER BUZZ

Navigating the Operational Challenges of Treatment with Bispecific Antibodies

MAR 28, 202410 MIN

Description

Advancements in clinical data and research have shown the immunotherapeutic potential of bispecific antibodies as treatment for hematologic cancers and solid tumors. In this episode, CANCER BUZZ speaks with Aaron Cumpston, PharmD, pharmacy clinical specialist for bone marrow transplant and Christine Barrett, PharmD, BCOP, medical oncology clinical pharmacy specialist who discuss the challenges of care coordination and therapy and share operational best practices for the delivery of bispecific antibodies in the community setting.  

 

“I think we’re finding these drugs to be highly effective and having high response rates and also very durable response rates in very refractory patients.”—Aaron Cumpston, PharmD, BCOP

“I know that in community practice it can be really difficult, but there is a network of institutions out there that have taken on administering these BiTE therapies and have a lot of experience that can be very helpful for those in community practice.” —Christine Barrett, PharmD, BCOP

 

Aaron Cumpston, PharmD, BCOP 

Pharmacy Clinical Specialist – Hematologic Malignancy, Transplant, and Cellular Therapy

WVU Medicine 

WVU Cancer Institute - Mary Babb Randolph Cancer Center 

Morgantown, WV 

 

Christine Barrett, PharmD, BCOP 

Medical Oncology Clinical Pharmacy Specialist 

WVU Medicine 

WVU Cancer Institute - Mary Babb Randolph Cancer Center 

Morgantown, WV 

 

This episode was developed in connection with the ACCC education program Sharing Operational Insights for the Delivery of Bispecific Antibodies in Solid Tumor and is supported by Amgen.

Resources:

Expanding Access to Cellular and Bispecific Therapies – Considerations and Recommendations by ACCC and SITC 

Sharing Operational Insights for the Delivery of Bispecific Antibodies in Solid Tumor 

Best Practices in Expanding Access to Bispecific Antibodies and Adverse Event Management