<a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new">Send me a derm question or story through text or voicemail!</a>Can cats safely take Apoquel or Zenrelia? In this episode, we take a deep dive into the use of JAK inhibitors in feline dermatology, exploring the science behind atopic disease, practical treatment considerations, and the realities of off-label medication use in cats. Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/ Follow Me: https://www.instagram.com/thedermvet/ Timestamps 00:00 Intro 01:31 Itch Inquiry: Atopic Dogs and the pathophysiology 04:22 JAK Inhibitors and Cats 05:58 Using Apoquel with a Cat  08:58 Using Zenrelia with a Cat 10:53 Dosing These Medications in Cats  12:35 Lab Work Monitoring the Cats 14:02 The Risk 14:25 The Duration 15:40 Discussion of Off Label Use with Owners 16:58 Outro

<description>&lt;p&gt;&lt;a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new"&gt;Send me a derm question or story through text or voicemail!&lt;/a&gt;&lt;/p&gt;&lt;p&gt;Can cats safely take Apoquel or Zenrelia? In this episode, we take a deep dive into the use of JAK inhibitors in feline dermatology, exploring the science behind atopic disease, practical treatment considerations, and the realities of off-label medication use in cats.&lt;br/&gt;&lt;br/&gt;Watch The Episode: https://www.youtube.com/@thedermvet3932&lt;br/&gt;Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/&lt;br/&gt;Follow Me: https://www.instagram.com/thedermvet/&lt;br/&gt;&lt;br/&gt;Timestamps&lt;br/&gt;00:00 Intro&lt;br/&gt;01:31 Itch Inquiry: Atopic Dogs and the pathophysiology&lt;br/&gt;04:22 JAK Inhibitors and Cats&lt;br/&gt;05:58 Using Apoquel with a Cat &lt;br/&gt;08:58 Using Zenrelia with a Cat&lt;br/&gt;10:53 Dosing These Medications in Cats &lt;br/&gt;12:35 Lab Work Monitoring the Cats&lt;br/&gt;14:02 The Risk&lt;br/&gt;14:25 The Duration&lt;br/&gt;15:40 Discussion of Off Label Use with Owners&lt;br/&gt;16:58 Outro&lt;/p&gt;</description>

Send me a derm question or story through text or voicemail! Can cats safely take Apoquel or Zenrelia? In this episode, we take a deep dive into the use of JAK inhibitors in feline dermatology, exploring the science behind atopic disease, practical treatment considerations, and the realities of off-label medication use in cats.  Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/ Follow Me: https://www.instagram.com/t...

328. Managing Itchy Cats: Apoquel, Zenrelia, and the Reality of Off-Label Treatment

<a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new">Send me a derm question or story through text or voicemail!</a>Skin barrier is having a moment... and for good reason. In this episode, I break down why restoring the skin barrier is a non-negotiable piece of the multimodal approach to managing atopic dermatitis in dogs and cats, and more importantly, how to actually do it when your clients can&apos;t keep up with a bathing schedule.Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/ Follow Me: https://www.instagram.com/thedermvet/Timestamps 00:00 Intro 00:45 Itch Inquiry: Recurrent Yeast Otitis 01:37 Antifungal Resistance in Malassezia 03:54 Underlying Allergies and Immunotherapy 06:29 Paronychia 07:19 Toothpick vs. Tape Methods 09:30 Treatment for Yeast 15:35 Summary/Outro

<description>&lt;p&gt;&lt;a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new"&gt;Send me a derm question or story through text or voicemail!&lt;/a&gt;&lt;/p&gt;&lt;p&gt;Skin barrier is having a moment... and for good reason. In this episode, I break down why restoring the skin barrier is a non-negotiable piece of the multimodal approach to managing atopic dermatitis in dogs and cats, and more importantly, how to actually do it when your clients can&amp;apos;t keep up with a bathing schedule.&lt;/p&gt;&lt;p&gt;Watch The Episode: https://www.youtube.com/@thedermvet3932&lt;br/&gt;Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/&lt;br/&gt;Follow Me: https://www.instagram.com/thedermvet/&lt;/p&gt;&lt;p&gt;Timestamps&lt;br/&gt;00:00 Intro&lt;br/&gt;00:45 Itch Inquiry: Recurrent Yeast Otitis&lt;br/&gt;01:37 Antifungal Resistance in Malassezia&lt;br/&gt;03:54 Underlying Allergies and Immunotherapy&lt;br/&gt;06:29 Paronychia&lt;br/&gt;07:19 Toothpick vs. Tape Methods&lt;br/&gt;09:30 Treatment for Yeast&lt;br/&gt;15:35 Summary/Outro &lt;/p&gt;</description>

Send me a derm question or story through text or voicemail! Skin barrier is having a moment... and for good reason. In this episode, I break down why restoring the skin barrier is a non-negotiable piece of the multimodal approach to managing atopic dermatitis in dogs and cats, and more importantly, how to actually do it when your clients can't keep up with a bathing schedule. Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thed...

327. A Practical Guide to Multimodal Skin Barrier Therapy in Allergic Dogs & Cats

<a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new">Send me a derm question or story through text or voicemail!</a>A new JAK inhibitor has officially entered the veterinary market but where does it fit into managing allergic dogs? In this episode of The Derm Vet Podcast, I sit down with boarded veterinary dermatologist Dr. Christine McKinney from Merck Animal Health to discuss Numelvi, the newest JAK inhibitor approved in the United States for canine allergic dermatitis. We break down what makes this medication unique, how it compares to other allergy therapies, and why having multiple treatment options matters when managing complicated allergic patients. We also dive into practical approaches for itch control, infection management, and building confidence when treating chronic allergy cases in practice. If you manage itchy dogs regularly and want to stay up to date on the latest dermatology treatments, this episode is packed with valuable clinical insights. Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/ Follow Me: https://www.instagram.com/thedermvet/ Timestamps and references: 7:26: At the recommended treatment dose, Numelvi is at least 10X more selective for JAK1 over the other JAK enzymes in in vitro assays. Reference: Kowalski T, Schuette S. The second-generation Janus kinase inhibitor atinvicitinib is a potent and highly selective inhibitor of JAK1. Vet Dermatol. 2026;37(2):179.8:03: At the recommended treatment dose, Numelvi is at least 10X more selective for JAK1 over the other JAK enzymes in in vitro assays. Reference: Kowalski T, Schuette S. The second-generation Janus kinase inhibitor atinvicitinib is a potent and highly selective inhibitor of JAK1. Vet Dermatol. 2026;37(2):179.8:07: JAK1 is the primary driver of itch and inflammation. Reference: Huang I, Chung W, Wu P, Chen C. JAK-STAT signaling pathway in the pathogenesis of atopic dermatitis: an updated review. Front Immunol. 2022;13:106826010:36: At the recommended treatment dose, Numelvi is at least 10X more selective for JAK1 over the other JAK enzymes in in vitro assays. Reference: Kowalski T, Schuette S. The second-generation Janus kinase inhibitor atinvicitinib is a potent and highly selective inhibitor of JAK1. Vet Dermatol. 2026;37(2):179.21:52: Numelvi, starts reducing itch within 2-4 hours in a canine interleukin-31 (cIL-31)-induced pruritus model Reference: Kowalski T, Prohaczik A, Locke K, Samson C, Hope K. The second-generation Janus kinase inhibitor atinvicitinib significantly reduces pruritus 2-4 hours after dosing dogs in a canine interleukin-31 model. Vet Dermatol. 2026;37(2):179-180.23:13: Numelvi, starts reducing itch within 2-4 hours in a canine interleukin-31 (cIL-31)-induced pruritus model Reference: Kowalski T, Prohaczik A, Locke K, Samson C, Hope K. The second-generation Janus kinase inhibitor atinvicitinib significantly reduces pruritus 2-4 hours after dosing dogs in a canine interleukin-31 model. Vet Dermatol. 2026;37(2):179-180. Timestamps 00:00 Intro 02:29 The Complexity of Canine Allergic Dermatitis 06:44 What is Numelvi and How Does it Work? 13:50 Dosing Guidelines and Tablet Specifications 16:57 Candidate Selection and Infection Control 21:37 Onset of Action and Efficacy Timeline 24:08 Final ThoughtsThis episode is sponsored by Merck Animal Health

<description>&lt;p&gt;&lt;a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new"&gt;Send me a derm question or story through text or voicemail!&lt;/a&gt;&lt;/p&gt;&lt;p&gt;A new JAK inhibitor has officially entered the veterinary market but where does it fit into managing allergic dogs?&lt;br/&gt;&lt;br/&gt;In this episode of The Derm Vet Podcast, I sit down with boarded veterinary dermatologist Dr. Christine McKinney from Merck Animal Health to discuss Numelvi, the newest JAK inhibitor approved in the United States for canine allergic dermatitis. We break down what makes this medication unique, how it compares to other allergy therapies, and why having multiple treatment options matters when managing complicated allergic patients.&lt;br/&gt;&lt;br/&gt;We also dive into practical approaches for itch control, infection management, and building confidence when treating chronic allergy cases in practice. If you manage itchy dogs regularly and want to stay up to date on the latest dermatology treatments, this episode is packed with valuable clinical insights.&lt;br/&gt;&lt;br/&gt;Watch The Episode: https://www.youtube.com/@thedermvet3932&lt;br/&gt;Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/&lt;br/&gt;Follow Me: https://www.instagram.com/thedermvet/&lt;/p&gt;&lt;p&gt;&lt;br/&gt;&lt;/p&gt;&lt;p&gt;Timestamps and references: &lt;/p&gt;&lt;p&gt;&lt;b&gt;&lt;br/&gt;7:26: &lt;/b&gt;At the recommended treatment dose, Numelvi is at least 10X more selective for JAK1 over the other JAK enzymes in &lt;em&gt;in vitro &lt;/em&gt;assays. Reference: Kowalski T, Schuette S. The second-generation Janus kinase inhibitor atinvicitinib is a potent and highly selective inhibitor of JAK1. Vet Dermatol. 2026;37(2):179.&lt;/p&gt;&lt;p&gt;&lt;b&gt;8:03:&lt;/b&gt; At the recommended treatment dose, Numelvi is at least 10X more selective for JAK1 over the other JAK enzymes in &lt;em&gt;in vitro &lt;/em&gt;assays. Reference: Kowalski T, Schuette S. The second-generation Janus kinase inhibitor atinvicitinib is a potent and highly selective inhibitor of JAK1. Vet Dermatol. 2026;37(2):179.&lt;/p&gt;&lt;p&gt;&lt;b&gt;8:07: &lt;/b&gt;JAK1 is the primary driver of itch and inflammation. Reference: Huang I, Chung W, Wu P, Chen C. JAK-STAT signaling pathway in the pathogenesis of atopic dermatitis: an updated review. Front Immunol. 2022;13:1068260&lt;/p&gt;&lt;p&gt;&lt;b&gt;10:36: &lt;/b&gt;At the recommended treatment dose, Numelvi is at least 10X more selective for JAK1 over the other JAK enzymes in &lt;em&gt;in vitro &lt;/em&gt;assays. Reference: Kowalski T, Schuette S. The second-generation Janus kinase inhibitor atinvicitinib is a potent and highly selective inhibitor of JAK1. Vet Dermatol. 2026;37(2):179.&lt;/p&gt;&lt;p&gt;&lt;b&gt;21:52:&lt;/b&gt; Numelvi, starts reducing itch within 2-4 hours in a canine interleukin-31 (cIL-31)-induced pruritus model Reference: Kowalski T, Prohaczik A, Locke K, Samson C, Hope K. The second-generation Janus kinase inhibitor atinvicitinib significantly reduces pruritus 2-4 hours after dosing dogs in a canine interleukin-31 model. Vet Dermatol. 2026;37(2):179-180.&lt;/p&gt;&lt;p&gt;&lt;b&gt;23:13: &lt;/b&gt;Numelvi, starts reducing itch within 2-4 hours in a canine interleukin-31 (cIL-31)-induced pruritus model Reference: Kowalski T, Prohaczik A, Locke K, Samson C, Hope K. The second-generation Janus kinase inhibitor atinvicitinib significantly reduces pruritus 2-4 hours after dosing dogs in a canine interleukin-31 model. Vet Dermatol. 2026;37(2):179-180.&lt;/p&gt;&lt;p&gt;&lt;br/&gt;&lt;br/&gt;Timestamps&lt;br/&gt;00:00 Intro&lt;br/&gt;02:29 The Complexity of Canine Allergic Dermatitis&lt;br/&gt;06:44 What is Numelvi and How Does it Work?&lt;br/&gt;13:50 Dosing Guidelines and Tablet Specifications&lt;br/&gt;16:57 Candidate Selection and Infection Control&lt;br/&gt;21:37 Onset of Action and Efficacy Timeline&lt;br/&gt;24:08 Final Thoughts&lt;/p&gt;&lt;p&gt;&lt;em&gt;This episode is sponsored by Merck Animal Health&lt;/em&gt;&lt;/p&gt;</description>

Send me a derm question or story through text or voicemail! A new JAK inhibitor has officially entered the veterinary market but where does it fit into managing allergic dogs?  In this episode of The Derm Vet Podcast, I sit down with boarded veterinary dermatologist Dr. Christine McKinney from Merck Animal Health to discuss Numelvi, the newest JAK inhibitor approved in the United States for canine allergic dermatitis. We break down what makes this medication unique, how it compares to other a...

326. New JAK Inhibitor for Allergic Dogs? What Vets Need to Know About Numelvi

<a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new">Send me a derm question or story through text or voicemail!</a>Skin barrier therapy has become one of the hottest topics in veterinary dermatology but with so many sprays, spot-ons, mousses, collars, and topical products available, it can be difficult to know what actually works and when to use them. In this week’s episode of The Derm Vet Podcast, we dive into the concept of skin barrier support and why managing allergic skin disease goes far beyond simply treating itch. I break down different categories of topical therapies, including AtopiVet products, spot-on formulations, mousse therapies, and skin care collars, while discussing how these products can fit into a multimodal dermatology plan. Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/ Follow Me: https://www.instagram.com/thedermvet/ Timestamps 00:00 Intro 01:40 The Itch Inquiry: Skin Barrier and Beyond Topicals 04:48 AtopiVet Products 08:04 Spot-On Products 09:23 Mousse Products 10:19 Skin Care Collar 12:44 Outro

<description>&lt;p&gt;&lt;a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new"&gt;Send me a derm question or story through text or voicemail!&lt;/a&gt;&lt;/p&gt;&lt;p&gt;Skin barrier therapy has become one of the hottest topics in veterinary dermatology but with so many sprays, spot-ons, mousses, collars, and topical products available, it can be difficult to know what actually works and when to use them.&lt;br/&gt;&lt;br/&gt;In this week’s episode of The Derm Vet Podcast, we dive into the concept of skin barrier support and why managing allergic skin disease goes far beyond simply treating itch. I break down different categories of topical therapies, including AtopiVet products, spot-on formulations, mousse therapies, and skin care collars, while discussing how these products can fit into a multimodal dermatology plan.&lt;br/&gt;&lt;br/&gt;Watch The Episode: https://www.youtube.com/@thedermvet3932&lt;br/&gt;Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/&lt;br/&gt;Follow Me: https://www.instagram.com/thedermvet/&lt;br/&gt;&lt;br/&gt;Timestamps&lt;br/&gt;00:00 Intro&lt;br/&gt;01:40 The Itch Inquiry: Skin Barrier and Beyond Topicals&lt;br/&gt;04:48 AtopiVet Products&lt;br/&gt;08:04 Spot-On Products&lt;br/&gt;09:23 Mousse Products&lt;br/&gt;10:19 Skin Care Collar&lt;br/&gt;12:44 Outro&lt;/p&gt;</description>

Send me a derm question or story through text or voicemail! Skin barrier therapy has become one of the hottest topics in veterinary dermatology but with so many sprays, spot-ons, mousses, collars, and topical products available, it can be difficult to know what actually works and when to use them.  In this week’s episode of The Derm Vet Podcast, we dive into the concept of skin barrier support and why managing allergic skin disease goes far beyond simply treating itch. I break down different ...

325. Top Skin Barrier Products Every Veterinary Team Should Know

<a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new">Send me a derm question or story through text or voicemail!</a>In this episode, I dive into the diagnostic approach and long-term management of sterile nodular panniculitis in veterinary patients. We discuss everything from sampling claw folds and interpreting flaky cytology samples to biopsy techniques, infectious disease rule-outs, and when to consider JAK inhibitors as part of a treatment plan.  If you’ve ever struggled with diagnosing challenging nodular cases or navigating long-term management decisions, this episode is packed with practical clinical insights you can apply in practice. Did you know you can submit a question or voicemail to the show by using the link at the top of the show notes? Send me any and all questions to be featured on an episode! Watch The Episode: https://www.youtube.com/@thedermvet3932 Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/ Follow Me: https://www.instagram.com/thedermvet/ Timestamps 00:00 Intro 01:14 Itch Inquiry: Sampling Claw Folds and Flaky Samples 06:00 Identifying Sterile Nodular Panniculitis 08:54 Diagnostic Approaches and Biopsy Techniques 09:56 Ruling Out Infectious Causes 12:53 Use of JAK Inhibitors 16:19 Long-term Management 19:49 Outro

<description>&lt;p&gt;&lt;a target="_blank" href="https://www.buzzsprout.com/736385/fan_mail/new"&gt;Send me a derm question or story through text or voicemail!&lt;/a&gt;&lt;/p&gt;&lt;p&gt;In this episode, I dive into the diagnostic approach and long-term management of sterile nodular panniculitis in veterinary patients. We discuss everything from sampling claw folds and interpreting flaky cytology samples to biopsy techniques, infectious disease rule-outs, and when to consider JAK inhibitors as part of a treatment plan. &lt;br/&gt;&lt;br/&gt;If you’ve ever struggled with diagnosing challenging nodular cases or navigating long-term management decisions, this episode is packed with practical clinical insights you can apply in practice.&lt;br/&gt;&lt;br/&gt;Did you know you can submit a question or voicemail to the show by using the link at the top of the show notes? Send me any and all questions to be featured on an episode!&lt;br/&gt;&lt;br/&gt;Watch The Episode: https://www.youtube.com/@thedermvet3932&lt;br/&gt;Follow The Derm Vet Podcast: https://www.instagram.com/thedermvetpod/&lt;br/&gt;Follow Me: https://www.instagram.com/thedermvet/&lt;br/&gt;&lt;br/&gt;Timestamps&lt;br/&gt;00:00 Intro&lt;br/&gt;01:14 Itch Inquiry: Sampling Claw Folds and Flaky Samples&lt;br/&gt;06:00 Identifying Sterile Nodular Panniculitis&lt;br/&gt;08:54 Diagnostic Approaches and Biopsy Techniques&lt;br/&gt;09:56 Ruling Out Infectious Causes&lt;br/&gt;12:53 Use of JAK Inhibitors&lt;br/&gt;16:19 Long-term Management&lt;br/&gt;19:49 Outro&lt;/p&gt;</description>

Send me a derm question or story through text or voicemail! In this episode, I dive into the diagnostic approach and long-term management of sterile nodular panniculitis in veterinary patients. We discuss everything from sampling claw folds and interpreting flaky cytology samples to biopsy techniques, infectious disease rule-outs, and when to consider JAK inhibitors as part of a treatment plan.   If you’ve ever struggled with diagnosing challenging nodular cases or navigating long-term m...

324. Biopsy Timing, Infectious Differentials & Managing Sterile Nodular Panniculitis

Tune in to make veterinary dermatology more fun than frustrating!  This podcast features Dr. Ashley Bourgeois, DVM, Dip ACVD sharing practical tips on dermatologic workups you can bring to clinical practice right away. Also, stories about navigating the messy (yet beautiful) journey of being a vet mom while building a career you love. 

The Derm Vet Podcast

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