<description>&lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; There is now a significant opportunity to improve the safety and quality of life outcomes for men requiring treatment for prostate cancer. &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Today, we're discussing the Water IV Prostate Cancer trial, an innovative and meaningful clinical trial that is actively enrolling patients to assess how the safety and efficacy of Aquablation therapy compares with radical prostatectomy in men with localized prostate cancer. I'm excited to share my experience as a current investigator for that study and to have Dr. Inderbir Gill, the co-principal investigator from the University of Southern California, join us. &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Dr. Gill is the current Chairman and Distinguished Professor of Urology of the University of Southern California Department of Urology. He is also the Founding Executive Director of the USC Institute of Urology.&lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Stay tuned to learn who qualifies as a candidate to participate in the trial, how the study works, and how you can get involved.&lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: italic; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Disclaimer: The Prostate Health Podcast is for informational purposes only. Nothing in this podcast should be construed as medical advice. By listening to the podcast, no physician-patient relationship has been formed. For more information and counseling, you must contact your personal physician or urologist with questions about your unique situation. &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: italic; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Pertinent disclosure for today's episode – Today's episode is sponsored by PROCEPT BioRobotics Corporation, which manufactures and sells the Aquablation system. Dr. Pohlman is also a paid advisor for PROCEPT BioRobotics Corporation.&lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 9pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Show Highlights:&lt;/span&gt;&lt;/p&gt; &lt;ul style= "margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;"&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 12pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; How the Water IV Prostate Cancer trial compares Aquablation directly with radical prostatectomy&lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; How the Water IV Prostate Cancer trial is the first prospective, randomized U.S. trial comparing a novel prostate cancer treatment to radical prostatectomy.&lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Who qualifies as an eligible participant for the Water IV Prostate Cancer trial?&lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; The requirements for those participating in the Water IV Prostate Cancer trial&lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; How the trial randomizes the participants in the trial&lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; What the study measures as its primary and secondary endpoints &lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; How recruitment for the trial has exceeded all expectations&lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;li dir="ltr" style= "list-style-type: disc; font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 27pt;" role= "presentation"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; When the early trial results should come out &lt;/span&gt;&lt;/p&gt; &lt;/li&gt; &lt;/ul&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Links: &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; WATER IV Prostate Cancer Study webpage:&lt;/span&gt; &lt;a style= "text-decoration: none;" href="http://water4pca.com"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; water4pca.com&lt;/span&gt;&lt;/a&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Contact the study team:&lt;/span&gt; &lt;a style="text-decoration: none;" href="mailto:wateriv@procept-biorobotics.com"&gt;&lt;span style= "font-size: 10pt; font-family: Roboto,sans-serif; color: #1155cc; background-color: #ffffff; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; wateriv@procept-biorobotics.com&lt;/span&gt;&lt;/a&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Aquablation Therapy website:&lt;/span&gt; &lt;a style= "text-decoration: none;" href= "https://aquablation.com/"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; https://aquablation.com/&lt;/span&gt;&lt;/a&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Follow Dr. Pohlman on Twitter and Instagram - @gpohlmanmd &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Get your free&lt;/span&gt; &lt;a style="text-decoration: none;" href= "http://www.prostatehealthpodcast.com/clinic"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #0000ff; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; What To Expect Guide&lt;/span&gt;&lt;/a&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; (or find the link on our&lt;/span&gt; &lt;a style="text-decoration: none;" href="http://www.prostatehealthpodcast.com/"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #0000ff; background-color: transparent; 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font-family: Verdana,sans-serif; color: #0000ff; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Facebook group&lt;/span&gt;&lt;/a&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Follow Dr. Pohlman on&lt;/span&gt; &lt;a style="text-decoration: none;" href="https://twitter.com/gpohlmanmd"&gt;&lt;span style= "font-size: 10pt; 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font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Sign up for the&lt;/span&gt; &lt;a style="text-decoration: none;" href= "https://www.prostatehealthacademy.com/"&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #0000ff; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; Prostate Health Academy&lt;/span&gt;&lt;/a&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt;  &lt;/span&gt;&lt;/p&gt; &lt;p dir="ltr" style= "line-height: 1.38; margin-top: 0pt; margin-bottom: 6pt;"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt; You can access Dr. Pohlman's free mini-webinar, where he discusses his top three tips to promote men's prostate health, longevity, and quality of life&lt;/span&gt; &lt;a style="text-decoration: none;" href= "https://www.prostatehealthacademy.com/opt-in-86d10314-5bae-42ca-9cb4-c9a5349fd0f9"&gt; &lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #0000ff; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;"&gt; here&lt;/span&gt;&lt;/a&gt;&lt;span style= "font-size: 10pt; font-family: Verdana,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;"&gt;.&lt;/span&gt;&lt;/p&gt; &lt;p&gt; &lt;/p&gt;</description>

The Prostate Health Podcast

Garrett Pohlman, MD

110: Evaluating Aquablation Therapy to Treat Prostate Cancer – WATER IV Prostate Cancer Trial – Inderbir S. Gill, MD

DEC 23, 202515 MIN
The Prostate Health Podcast

110: Evaluating Aquablation Therapy to Treat Prostate Cancer – WATER IV Prostate Cancer Trial – Inderbir S. Gill, MD

DEC 23, 202515 MIN

Description

There is now a significant opportunity to improve the safety and quality of life outcomes for men requiring treatment for prostate cancer. Today, we're discussing the Water IV Prostate Cancer trial, an innovative and meaningful clinical trial that is actively enrolling patients to assess how the safety and efficacy of Aquablation therapy compares with radical prostatectomy in men with localized prostate cancer. I'm excited to share my experience as a current investigator for that study and to have Dr. Inderbir Gill, the co-principal investigator from the University of Southern California, join us. Dr. Gill is the current Chairman and Distinguished Professor of Urology of the University of Southern California Department of Urology. He is also the Founding Executive Director of the USC Institute of Urology. Stay tuned to learn who qualifies as a candidate to participate in the trial, how the study works, and how you can get involved. Disclaimer: The Prostate Health Podcast is for informational purposes only. Nothing in this podcast should be construed as medical advice. By listening to the podcast, no physician-patient relationship has been formed. For more information and counseling, you must contact your personal physician or urologist with questions about your unique situation. Pertinent disclosure for today's episode – Today's episode is sponsored by PROCEPT BioRobotics Corporation, which manufactures and sells the Aquablation system. Dr. Pohlman is also a paid advisor for PROCEPT BioRobotics Corporation. Show Highlights: How the Water IV Prostate Cancer trial compares Aquablation directly with radical prostatectomy How the Water IV Prostate Cancer trial is the first prospective, randomized U.S. trial comparing a novel prostate cancer treatment to radical prostatectomy. Who qualifies as an eligible participant for the Water IV Prostate Cancer trial? The requirements for those participating in the Water IV Prostate Cancer trial How the trial randomizes the participants in the trial What the study measures as its primary and secondary endpoints How recruitment for the trial has exceeded all expectations When the early trial results should come out Links: WATER IV Prostate Cancer Study webpage: water4pca.com Contact the study team: [email protected] Aquablation Therapy website: https://aquablation.com/ Follow Dr. Pohlman on Twitter and Instagram - @gpohlmanmd Get your free What To Expect Guide (or find the link on our podcast website) Join our Facebook group Follow Dr. Pohlman on Twitter and Instagram Sign up for the Prostate Health Academy You can access Dr. Pohlman's free mini-webinar, where he discusses his top three tips to promote men's prostate health, longevity, and quality of life here.