The MOTS-c Masterclass | Complete Researcher’s Guide (2026)

JUN 30, 202647 MIN
The Hunter Williams Podcast

The MOTS-c Masterclass | Complete Researcher’s Guide (2026)

JUN 30, 202647 MIN

Description

<p>Links, cheatsheet, private group and more: <a href="https://hunterwilliamshealth.com/links">⁠https://hunterwilliamshealth.com/links</a></p><p><br></p><p>In this masterclass I break down what MOTS-c actually is. It&#39;s a tiny peptide your mitochondria make when you exercise. It&#39;s the only major peptide coded inside the mitochondrial genome, not the cell nucleus.</p><p>I get into how it flips the AMPK switch, your cell&#39;s main fuel gauge. I cover the dual action that lets it travel into the nucleus and turn on antioxidant genes. That part makes it pretty unique.</p><p>Then I walk through the practical stuff. Who&#39;s a good candidate and who should skip it. My full dosing tiers, from a 250mcg screening dose up to 5mg. Cycling, reconstitution, and how I pair it with SS-31 and humanin.</p><p>I also cover the side effect nobody warns you about. Around 10% of people react badly, and some of those reactions are serious. That&#39;s why I start low and work up slowly.</p><p>A heads up on the evidence. Most of the exciting data is still animal models. Human data is thin, so I flag where I&#39;m extrapolating.</p><p>MOTS-c is more bioactive than its reputation suggests. Treat it with respect and it rewards you.</p><p><br></p>