<description>&lt;h3&gt;Show Notes&lt;/h3&gt;&lt;p&gt;In this special live episode from the &lt;strong&gt;2025 North American Congress of Clinical Toxicology (NACCT)&lt;/strong&gt;, Ryan takes you inside the poster hall to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year’s highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more.&lt;/p&gt;&lt;p&gt;If you couldn’t make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one.&lt;/p&gt;&lt;p&gt;&lt;a href="https://www.tandfonline.com/doi/full/10.1080/15563650.2025.2532975" rel="noopener noreferrer" target="_blank"&gt;&lt;em&gt;Link to published abstract manuscript&lt;/em&gt;&lt;/a&gt;&lt;/p&gt;&lt;h3&gt;Preamble with Dr. Jon Cole&lt;/h3&gt;&lt;h3&gt;&lt;br&gt;&lt;/h3&gt;&lt;p&gt;09:20&lt;strong&gt; - &lt;/strong&gt;Abstract #7. Is beta blocker toxicity associated with hypoglycemia?&lt;/p&gt;&lt;ul&gt;&lt;li&gt;First author: Dr. Megan Audette&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;17:00 - Abstract #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparison&lt;/p&gt;&lt;ul&gt;&lt;li&gt;First author:Dr. Daniel Tirado&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;26:50 - Abstract #247. Blocked but not beaten: ECMO’s role in severe amlodipine toxicity – a poison center case series?&lt;/p&gt;&lt;ul&gt;&lt;li&gt;First author: Dr. Carlos Saldarriaga&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;28:15 Abstract #27. Amlodipine double-dose therapeutic errors reported to Poison Centers&lt;/p&gt;&lt;ul&gt;&lt;li&gt;First author: Carlos Saldarriaga&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;29:00 Abstract #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison center&lt;/p&gt;&lt;ul&gt;&lt;li&gt;First author: Dr. Tiana Patriarca&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;32:38 - 292. Intravenous administration of sodium zirconium cyclosilicate resulting in death&lt;/p&gt;&lt;ul&gt;&lt;li&gt;First author:  Dr. Stephen Thornton&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;h3&gt;Abstracts &amp;amp; Guests&lt;/h3&gt;&lt;h3&gt;&lt;br&gt;&lt;/h3&gt;&lt;p&gt;40:06&lt;strong&gt; – Abstract #21. Quantitative analysis of amlodipine removal by plasmapheresis&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Keahi Horowitz, MD – Acute and Intensive Care Research Award winner&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;44:00 &lt;strong&gt;– Abstract #23. Relationship between reported ingestion dose and outcome in amlodipine poisoning&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Colleen Cowdery, MD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;47:30 &lt;strong&gt;– Abstract #24. Management of severe amlodipine toxicity with high-dose calcium alone&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Vincent Ma, MD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;53:00 &lt;strong&gt;– Abstract #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patient&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Connor Young, MD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;55:51&lt;strong&gt; – Abstract #182. Left in the dark: a case of blindness in the setting of metformin toxicity&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Madison Bompard, MD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;&lt;strong&gt;57:56 – Abstract #169. Just because it’s natural doesn’t mean it’s safe: a case of pediatric toxicity from topical and herbal remedies&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Aria Darling, MD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;59:57&lt;strong&gt; – Abstract #203. Serotonin syndrome after vaping "Moocah"&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Connor Murphy, DO&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;&lt;strong&gt;1:03:00 – Abstract #307. Intravenous ozone autohemotherapy: a retrospective observational case series&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Nicole McLarty &lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;1:05:59 &lt;strong&gt;– Abstract #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function tests but no detectable acetaminophen&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Seth Carroll PharmD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;1:09:30 –&lt;strong&gt; Abstract #130. Outcomes of acute acetaminophen-poisoned patients treated with and without fomepizole: a Toxic registry study&lt;/strong&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Guest: Dr. Jordan Woollum, PharmD&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;1:15:30&lt;strong&gt; – Abstract #295. Evaluation of onset...</description>

The Poison Lab

Clinical Toxicology LLC

LIVE from Chicago: 2025 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology

SEP 24, 202594 MIN
The Poison Lab

LIVE from Chicago: 2025 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology

SEP 24, 202594 MIN

Description

Show NotesIn this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the poster hall to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year’s highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more.If you couldn’t make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one.Link to published abstract manuscriptPreamble with Dr. Jon Cole09:20 - Abstract #7. Is beta blocker toxicity associated with hypoglycemia?First author: Dr. Megan Audette17:00 - Abstract #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparisonFirst author:Dr. Daniel Tirado26:50 - Abstract #247. Blocked but not beaten: ECMO’s role in severe amlodipine toxicity – a poison center case series?First author: Dr. Carlos Saldarriaga28:15 Abstract #27. Amlodipine double-dose therapeutic errors reported to Poison CentersFirst author: Carlos Saldarriaga29:00 Abstract #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison centerFirst author: Dr. Tiana Patriarca32:38 - 292. Intravenous administration of sodium zirconium cyclosilicate resulting in deathFirst author: Dr. Stephen ThorntonAbstracts & Guests40:06 – Abstract #21. Quantitative analysis of amlodipine removal by plasmapheresisGuest: Dr. Keahi Horowitz, MD – Acute and Intensive Care Research Award winner44:00 – Abstract #23. Relationship between reported ingestion dose and outcome in amlodipine poisoningGuest: Dr. Colleen Cowdery, MD47:30 – Abstract #24. Management of severe amlodipine toxicity with high-dose calcium aloneGuest: Dr. Vincent Ma, MD53:00 – Abstract #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patientGuest: Dr. Connor Young, MD55:51 – Abstract #182. Left in the dark: a case of blindness in the setting of metformin toxicityGuest: Madison Bompard, MD57:56 – Abstract #169. Just because it’s natural doesn’t mean it’s safe: a case of pediatric toxicity from topical and herbal remediesGuest: Dr. Aria Darling, MD59:57 – Abstract #203. Serotonin syndrome after vaping "Moocah"Guest: Dr. Connor Murphy, DO1:03:00 – Abstract #307. Intravenous ozone autohemotherapy: a retrospective observational case seriesGuest: Nicole McLarty 1:05:59 – Abstract #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function tests but no detectable acetaminophenGuest: Dr. Seth Carroll PharmD1:09:30 – Abstract #130. Outcomes of acute acetaminophen-poisoned patients treated with and without fomepizole: a Toxic registry studyGuest: Dr. Jordan Woollum, PharmD1:15:30 – Abstract #295. Evaluation of onset and resolution of complications after chronic methotrexate poisoningGuest: Dr. Van Quach, PharmD1:19:13 – Abstract #325. Implications of potassium in salicylate toxicity treated with urinary alkalinizationGuest: Dr. Andrew Yetka, PharmDSupport the showReview the show where ever your listeningGet Messages from Toxo (Join the Newsletter!)Join as a supporting memberAd free episodesBonus content and early accessDiscounts and give aways on GOTA PICCEM Mushroom card gameThe GOTTA PICCEM Poisonous Mushroom Game! Tox trinkets (Rep the show at home!)Reach the showEmail: [email protected] Show ResourcesRyan's Medical Games and ResourcesShow Website