<description>&lt;p&gt;Phenibut is an emerging and unfamiliar drug taking hold in the US that is readily available online and legal to obtain. It acts as a GABA-B agonist and carries risks of dependency and withdrawal. In this episode Ryan interviews phenibut users as well as experts involved in phenibut treatment. They explore the history, current trends, toxicity, and management of phenibut, a novel GABA-B agonist. He is joined by guest Dr. Matthew Stanton PharmD and Dr. Benjamin Weston MD who listen in to an audio documentary that includes clips from Dr. Janessa Graves PhD and Dr. Erica Liebelt MD who wrote a recent report on increasing phenibut exposures, Dr. Dan McCabe MD who is the author of the largest published phenibut case series, and Elliot, a recovered phenibut user who we would like to sincerely thank for sharing his story of use and recovery.&lt;/p&gt;&lt;p&gt;&lt;a href="https://pubmed.ncbi.nlm.nih.gov/38112312/" rel="noopener noreferrer" target="_blank"&gt;+Update- a systematic review of phenibut withdrawal treatment strategies authored by the poison lab host himeself, Ryan!+&lt;/a&gt;&lt;/p&gt;&lt;ul&gt;&lt;li&gt;&lt;a href="https://www.renalfellow.org/2020/07/29/st-anthonys-fire-ergot-and-the-kidney/" rel="noopener noreferrer" target="_blank"&gt;More on St Anthony's fire &lt;/a&gt;&lt;/li&gt;&lt;li&gt;&lt;a href="https://www.cdc.gov/mmwr/volumes/69/wr/mm6935a5.htm" rel="noopener noreferrer" target="_blank"&gt;CDC MWR Study documenting increased poison center exposures (Dr. Graves &amp;amp; Dr. Liebelt)&lt;/a&gt;&lt;/li&gt;&lt;li&gt;&lt;a href="https://pubmed.ncbi.nlm.nih.gov/30878413/" rel="noopener noreferrer" target="_blank"&gt; Phenibut case series from Dr. McCabe &lt;/a&gt;&lt;/li&gt;&lt;li&gt;&lt;a href="https://docs.google.com/spreadsheets/d/1OV9mktl-sHuWk_tzfM_tS2TIn2Rpb7jE7-nyJTzDs0c/edit#gid=0" rel="noopener noreferrer" target="_blank"&gt;All published cases of phenibut withdrawal, reported baclofen regimens, clinical outcomes, multimodal therapies&lt;/a&gt;&lt;/li&gt;&lt;li&gt;&lt;a href="https://docs.google.com/presentation/d/13vPDw_37Br3d8lENnvNO3NT4r9XvJpUeg5m_8Wg-88k/edit#slide=id.p" rel="noopener noreferrer" target="_blank"&gt;THEORETICAL UNTESTED Phenibut withdrawal treatment schema (Not tested, not intended as treatment, intended to stimulate discussion and highlight key considerations in managing withdrawal)&lt;/a&gt;&lt;/li&gt;&lt;/ul&gt;&lt;br/&gt;&lt;p&gt;&lt;h2&gt;Support the show&lt;/h2&gt;&lt;p&gt;Review the show where ever your listening&lt;/p&gt;&lt;p&gt;&lt;a href="https://thepoisonlab.aweb.page/p/cf635c33-5117-4652-abd6-6bedce51444a" rel="noopener noreferrer" target="_blank"&gt;Get Messages from Toxo (Join the Newsletter!)&lt;/a&gt;&lt;/p&gt;&lt;p&gt;&lt;a href="https://www.thepoisonlab.com/support" rel="noopener noreferrer" target="_blank"&gt;Join as a supporting member&lt;/a&gt;&lt;/p&gt;&lt;ol&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;Ad free episodes&lt;/li&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;Bonus content and early access&lt;/li&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;Discounts and give aways on GOTA PICCEM Mushroom card game&lt;/li&gt;&lt;/ol&gt;&lt;br/&gt;&lt;p&gt;&lt;a href="www.GOTTAPICCEM.com" rel="noopener noreferrer" target="_blank"&gt;The GOTTA PICCEM Poisonous Mushroom Game!&lt;/a&gt;&lt;/p&gt;&lt;p&gt;&lt;a href="https://a.co/d/46LP0n9" rel="noopener noreferrer" target="_blank"&gt;The Poisonus Fungus Amongus Children's Book!&lt;/a&gt;&lt;/p&gt;&lt;ol&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;&lt;a href="https://www.youtube.com/shorts/gfg6bgxB-ZY" rel="noopener noreferrer" target="_blank"&gt;Full book reading (6 minutes!)&lt;/a&gt;&lt;/li&gt;&lt;/ol&gt;&lt;br/&gt;&lt;p&gt;&lt;a href="https://www.etsy.com/shop/ThePoisonLab" rel="noopener noreferrer" target="_blank"&gt;Tox trinkets (Rep the show at home!)&lt;/a&gt;&lt;/p&gt;&lt;h2&gt;Reach the show&lt;/h2&gt;&lt;ol&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;Email: Toxtalk1@gmail.com&lt;/li&gt;&lt;/ol&gt;&lt;br/&gt;&lt;p&gt;More Show Resources&lt;/p&gt;&lt;ol&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;&lt;a href="https://the-poison-lab.yolasite.com/" rel="noopener noreferrer" target="_blank"&gt;Ryan's Medical Games and Resources&lt;/a&gt;&lt;/li&gt;&lt;li data-list="bullet"&gt;&lt;span class="ql-ui" contenteditable="false"&gt;&lt;/span&gt;&lt;a href="https://www.thepoisonlab.com" rel="noopener noreferrer" target="_blank"&gt;Show Website&lt;/a&gt;&lt;/li&gt;&lt;/ol&gt;&lt;br/&gt;&lt;/p&gt;</description>

The Poison Lab

Clinical Toxicology LLC

Rebroadcast: Phenibut. The emerging drug you don’t know about (yet)

MAY 4, 202666 MIN
The Poison Lab

Rebroadcast: Phenibut. The emerging drug you don’t know about (yet)

MAY 4, 202666 MIN

Description

Phenibut is an emerging and unfamiliar drug taking hold in the US that is readily available online and legal to obtain. It acts as a GABA-B agonist and carries risks of dependency and withdrawal. In this episode Ryan interviews phenibut users as well as experts involved in phenibut treatment. They explore the history, current trends, toxicity, and management of phenibut, a novel GABA-B agonist. He is joined by guest Dr. Matthew Stanton PharmD and Dr. Benjamin Weston MD who listen in to an audio documentary that includes clips from Dr. Janessa Graves PhD and Dr. Erica Liebelt MD who wrote a recent report on increasing phenibut exposures, Dr. Dan McCabe MD who is the author of the largest published phenibut case series, and Elliot, a recovered phenibut user who we would like to sincerely thank for sharing his story of use and recovery.+Update- a systematic review of phenibut withdrawal treatment strategies authored by the poison lab host himeself, Ryan!+More on St Anthony's fire CDC MWR Study documenting increased poison center exposures (Dr. Graves & Dr. Liebelt) Phenibut case series from Dr. McCabe All published cases of phenibut withdrawal, reported baclofen regimens, clinical outcomes, multimodal therapiesTHEORETICAL UNTESTED Phenibut withdrawal treatment schema (Not tested, not intended as treatment, intended to stimulate discussion and highlight key considerations in managing withdrawal)Support the showReview the show where ever your listeningGet Messages from Toxo (Join the Newsletter!)Join as a supporting memberAd free episodesBonus content and early accessDiscounts and give aways on GOTA PICCEM Mushroom card gameThe GOTTA PICCEM Poisonous Mushroom Game!The Poisonus Fungus Amongus Children's Book!Full book reading (6 minutes!)Tox trinkets (Rep the show at home!)Reach the showEmail: [email protected] Show ResourcesRyan's Medical Games and ResourcesShow Website