Jesse Ross had so much going for him. A 19-year-old sophomore at the University of Missouri at Kansas City, he was headed to Chicago for the second time to take part in a model United Nations program. But when Jesse got up and walked out of the conference room at about 2:30 AM during a break for a mock emergency meeting, a real-life disaster was in the making. 

Alarms were raised the next day when it came time for fellow students to head back to Kansas City and Jesse was nowhere to be found. Police were eventually called, along with Jesse's parents, and an investigation was launched, but in the 18 years since Jesse walked out of that conference room, not a trace of him has been found. 

What happened to Jesse that chilly November night? Did he, under the influence of alcohol, end up in the river, his body washed away forever? Did he encounter a nefarious person or persons upon exiting the hotel? Or did something happen to Jesse within the premises, the evidence being covered up?

Returning guest Joann Li is back--join us as we talk through the details and speculate about what could have happened to Jesse. 

If you have any information on the disappearance of Jesse Ross, contact the Chicago Police Department at 312-744-8266.

To support the search for Jesse, visit http://www.findjesseross.com

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One Minute and Forty-Three Seconds is dedicated to my number one fan. Thank you, Dad. I love you, and I miss you.