ASH 2025 | What are the key findings from the 12-month primary endpoint analysis of the ROP-ET phase III study?
DEC 15, 20257 MIN
ASH 2025 | What are the key findings from the 12-month primary endpoint analysis of the ROP-ET phase III study?
DEC 15, 20257 MIN
Description
<p>During the 67th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6–9, 2025, Orlando, US, the MPN Hub was pleased to speak with <a href="https://mpn-hub.com/contributors/jean-jacques-kiladjian" rel="noopener noreferrer" target="_blank">Jean-Jacques Kiladjian</a>, Université Paris Cité, Paris, FR. We asked, What are the key findings from the 12-month primary endpoint analysis of the ROP-ET phase III study? </p><br><p>In this interview, Kiladjian first provided an overview of the phase III <a href="https://mpn-hub.com/trials/rop-et" rel="noopener noreferrer" target="_blank">ROP-ET</a> (<a href="https://clinicaltrials.gov/study/NCT06514807" rel="noopener noreferrer" target="_blank">NCT06514807</a>) study design and key patient eligibility criteria. He then discussed the primary endpoint results, highlighting that the ROP-ET study met the primary endpoint – a composite durable hematologic and clinical response after 12 months. Finally, Kiladjian explored the safety profile of <a href="https://mpn-hub.com/therapeutics/immune-modulators/ropeginterferon-alfa-2b" rel="noopener noreferrer" target="_blank">ropeginterferon alfa-2b</a> observed in the study.</p><br><p><em>This educational resource is independently supported by AOP Health. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource.</em> </p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>