ReThinking

What do you think will make you happy next year? According to Dan Gilbert’s research, your guess is probably wrong. Dan is a Harvard psychologist, bestselling author of Stumbling on Happiness, and popular TED talker, and he and Adam discuss why it’s so difficult to make accurate predictions about our own future and how to figure out what actually makes us happy. The two also chat about Dan’s experience as a high school dropout-turned-professor, examine why small annoyances might hang around longer than major gripes, and determine the best way to end a conversation.

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Megan Rapinoe and Sue Bird are two of the greatest athletes of all time — Megan is an Olympic gold medalist and was named the best soccer player in the world by FIFA. Sue has won five of her own Olympic gold medals in basketball and four WNBA championships. Now that the couple have each retired from their legendary sports careers, they host a podcast together, a Touch More, and continue to play a major role in the meteoric rise of women’s sports. They talk with Adam about how to make a team great and leadership lessons from sports. They also discuss their difficult decisions to retire, and how to know when it’s time to let go and move on.

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David Fajgenbaum had his last rites read to him at 25 years old after a brutal struggle with an inflammatory disease that attacks the vital organs. As a medical student with two weeks left to live, he repurposed a drug and tested it on himself—and saved his own life. Now, he’s repeating the same process for many others through his nonprofit, Every Cure, with the mission of unlocking the full potential of existing drugs to treat every disease possible. David and Adam discuss the building blocks of resilience, explore the disincentives that prevent hidden cures from coming to light, and explain how AI is aiding creative discovery to save lives.

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Do you ever wish you could hibernate like a bear during the winter? Vladyslav Vyazovskiy thinks it might be possible. As a sleep physiologist at Oxford, Vladyslav studies why humans sleep and the sleep patterns of other species. He and Adam discuss the possibility of unlocking a hibernation ability in humans and its potential benefits – from curing cancer to enabling interplanetary travel. They also debunk some popular sleep misconceptions, debate the value of napping, and uncover just how little we really know about the science of sleep.