Integrative Lyme Solutions with Dr. Karlfeldt

Why do so many Lyme patients test negative while feeling anything but healthy? This is a special re-release of a powerful episode originally recorded in 2025. We felt it was too important not to bring back, especially as more people continue to struggle with confusing lab results and unanswered symptoms. The insights shared here are just as relevant today, if not more, and deserve to be heard again. In this episode of Integrative Lyme Solutions, Dr. Michael Karlfeldt breaks down the confusing world of Lyme disease testing and reveals why conventional lab results often fail chronic illness patients. Drawing insights from leading experts like Dr. Bruce Patterson and Dr. Joseph Burrascano, this episode uncovers the limitations of ELISA, Western Blot, and PCR testing and why they were never designed for complex, chronic cases. You will learn how Lyme evades detection, why immune dysfunction leads to false negatives, and how advanced testing methods like cytokine panels, T-cell testing, and FISH are reshaping diagnosis. If you have ever been told your labs are normal while your body says otherwise, this episode will change how you understand your health and your next steps forward. Key Takeaways: 0:00 Introduction 2:05 ELISA and Western Blot were never built for chronic Lyme 6:10 Immune dysfunction leads to false negatives 10:30 PCR testing limitations and missed infections 12:00 Expanding beyond standard labs into specialty testing 17:00 FISH testing detecting live organisms in the blood 22:00 Why combining tests gives a clearer diagnosis 23:30 Immune system testing the future of Lyme detection 28:00 Symptom patterns reveal different infections 30:15 Choosing the right test based on your stage 32:00 When to stop testing and start healing Resources Mentioned: ArminLabs https://arminlabs.com/ IGeneX https://igenex.com/ Galaxy Diagnostics https://www.galaxydx.com/ DNA Connexions https://dnaconnexions.com/ IncellDX https://incelldx.com/ Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What happens when Lyme disease is repeatedly dismissed even when the symptoms are clear? In this episode of Integrative Lyme Solutions, Dr. K speaks with Lyme advocate Amy Rose, who spent more than eight years searching for answers after being infected by a tick bite in 2008. Within days she developed severe flu-like symptoms and later discovered a large bullseye rash on her shoulder. Despite these classic warning signs, doctors repeatedly told her Lyme disease was impossible because she had been bitten in Arkansas. Multiple tests came back negative and she was given numerous misdiagnoses and medications instead of answers. Amy shares how her health continued to decline while she saw 27 doctors before finally receiving a proper diagnosis from a Lyme-literate practitioner. She also explains how this experience led her to start the Arkansas Lyme Foundation to support patients in a state where Lyme disease is still widely denied. Her story reveals the serious gaps in Lyme testing, the consequences of misdiagnosis, and the power of patient advocacy. Key Takeaways: 0:00 Introduction 2:15 Amy Rose’s Lyme infection and early symptoms in 2008 6:40 The bullseye rash and why Lyme was still missed 10:30 Five negative tests through Labcorp and misdiagnosis 16:50 Neurological Lyme and being misdiagnosed with Alzheimer’s 22:10 Losing the ability to drive due to brain inflammation 26:30 Finding a Lyme-literate doctor after seeing 27 physicians 32:45 Starting the Arkansas Lyme Foundation 38:20 Why Arkansas still denies Lyme disease exists 44:15 Reaching remission and focusing on cellular health and mold detox Resources Mentioned: Arkansas Lyme Foundation - https://www.arkansaslyme.org/ Labcorp - https://www.labcorp.com/ Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What if Alzheimer’s, multiple sclerosis, chronic fatigue, and even psychiatric symptoms are not random but driven by hidden infections? In this episode of Integrative Lyme Solutions, Dr. K sits down with research scientist and Lyme survivor Nikki Schultek to explore the infection hypothesis behind chronic disease. After battling years of misdiagnosed symptoms including asthma flares, interstitial cystitis, arrhythmias, neurological decline, and suspected MS, Nikki uncovered a complex web of infections including Borrelia, Bartonella, Babesia, Chlamydia pneumoniae, Epstein-Barr virus, and more. Now founder of the Alzheimer’s Pathobiome Initiative, Nikki is leading a global consortium investigating how stealth pathogens may trigger neurodegeneration, immune dysfunction, and dementia. This conversation dives into intracellular infections, the Herxheimer reaction, amyloid as an antimicrobial response, sterile brain autopsies, precision medicine, and why federal health agencies are finally acknowledging Lyme disease as a serious public health crisis. If you or someone you love is dealing with chronic Lyme, long COVID, autoimmune illness, or cognitive decline, this episode may change how you see disease. Key Takeaways: 0:00 Introduction 3:15 Asthma, air hunger, and early misdiagnoses 8:40 From interstitial cystitis to suspected multiple sclerosis 14:30 Discovering intracellular infections and Chlamydia pneumoniae 18:45 Lyme, Bartonella, Babesia and the whack-a-mole effect 24:10 The Pathobiome concept and microbial imbalance 27:30 Alzheimer’s disease and the infection hypothesis 32:00 Sterile brain autopsies and spinal fluid research 35:20 Amyloid plaque as an antimicrobial defense mechanism 41:00 APOE4, genetics, and infection susceptibility 44:30 Federal recognition of Lyme disease and future funding Resources Mentioned: Alzheimer’s Pathobiome Initiative - https://alzheimerspathobiome.org ILADS - https://www.ilads.org ILADS Education Foundation - https://www.iladef.org Philadelphia College of Osteopathic Medicine - https://www.pcom.edu Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What happens when Lyme disease goes undiagnosed for 15 years — and the emotional toll becomes just as devastating as the physical symptoms?In this episode of Integrative Lyme Solutions, Dr. K sits down with Susan Pogorzelski, author of The Last Letter: A Novel and founder of the Lyme Brave Foundation. Susan shares her 30-year journey through misdiagnosis, neurological decline, co-infections like Babesia, severe fatigue, psychiatric symptoms, and the long road of recovery. From being dismissed by doctors to experiencing suicidal ideation during treatment, Susan opens up about the isolation, trauma, and resilience that shaped her healing.This powerful conversation explores Lyme misdiagnosis, Babesia treatment, herxing, emotional trauma, nervous system regulation, EFT tapping, relapse recovery, and how chronic illness can reshape identity. If you or a loved one is navigating chronic Lyme disease, co-infections, or the emotional weight of invisible illness, this episode is both validation and hope.Key Takeaways:0:00 Introduction3:15 15 years of misdiagnosis and declining neurological health8:20 Gallbladder surgery, rapid deterioration, and ER visits12:05 Lyme diagnosis and multiple co-infections confirmed15:40 Babesia treatment and what moved the needle in recovery19:30 Herx reactions, suicidal ideation, and psychological symptoms23:50 Emotional trauma, loneliness, and invisible illness27:45 EFT tapping, nervous system healing, and energetic tools30:10 Relapses, flares, and building resilience over time33:00 Lyme Brave Foundation and supporting patients emotionallyResources Mentioned:Susan Pogorzelski Website - https://www.susanpogorzelski.com/aboutLyme Brave Foundation - https://lymebravefoundation.orgThe Last Letter: A Novel by Susan Pogorzelski - https://www.amazon.com/Last-Letter-Novel-Susan-Pogorzelski/dp/0988875136Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.#Babesia #InvisibleIllness #ChronicLyme _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Is chronic babesiosis finally getting the scientific attention it deserves?In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Geoff Dow, CEO & President of Sixty Degrees Pharmaceuticals, to discuss a groundbreaking clinical trial targeting chronic babesiosis — a common and often overlooked Lyme co-infection. Originally developed for malaria prevention, the drug Tafenoquine (brand name Kodatef®) is now being studied for its potential to treat persistent Babesia infections and Lyme-related fatigue.They explore the science behind red blood cell parasites, how Babesia differs from malaria, why chronic babesiosis remains controversial, and what makes this new trial the first FDA-reviewed IND study focused on chronic disease. If you or a loved one struggle with Lyme-related fatigue, relapsing babesiosis, or limited treatment options, this conversation offers cautious optimism and a closer look at the future of targeted therapies.Key Takeaways:0:00 Introduction3:10 From Malaria Drug Development to Lyme Co-Infections6:45 How Babesia Infects Red Blood Cells and Causes Fatigue10:40 Why Chronic Babesiosis Is Still Controversial14:50 No FDA-Approved Drugs Specifically for Babesiosis18:30 New Clinical Trials for Chronic and Relapsing Babesiosis24:00 Measuring Fatigue as a Primary Endpoint in Chronic DiseaseResources Mentioned:Sixty Degrees Pharmaceuticals - https://www.sixtydegreespharma.comKodatef® (Tafenoquine) Information - Available via company website aboveMount Sinai (Clinical Trial Site) - https://www.mountsinai.orgYale Babesiosis Case Series (Referenced Study) - https://medicine.yale.eduMedical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!