Peter was kind enough to allow me to re-release our interview from 2019 from his podcast, The Drive, Episode #69. Many people have found me through Peter and told me this was one of their favorite episodes. Aside from insulin resistance and metabolism, we end the discussion with a topic that really resonated with Peter, which is the impact of generational stress, social media, and devices on youth and how I've navigated this in my own personal life.  This is longer than my usual episodes since we cover a ton of important topics, so I included detailed timestamps below. I hope you enjoy this important conversation.  <ul> <li>Peter's overview and perspective on our discussion (0:58)</li> <li>Surprise moment for Peter from our discussion (2:30)</li> <li>How a tough case of insulin resistance led Peter to my work (5:08)</li> <li>Metabolic disease in South Asian and East Asian patients (5:54)</li> <li>Triglyceride paradox in African Americans (10:38)</li> <li>Visceral vs subcutaneous fat and shortcomings of BMI (11:30)</li> <li>Cortisol and glucose variability (25:00)</li> <li>Mechanistic discussion of insulin resistance (27:20)</li> <li>Origins and evolutionary theories on insulin resistance (37:00)</li> <li>Brown adipose tissue and impact of climate patterns on insulin resistance (46:43)</li> <li>Vitamin D and hyperinsulinemia (50:38)</li> <li>Uric acid, high blood pressure, and fructose metabolism(54:05)</li> <li>VO2 max and Zone 2, including ethnic diferences (56:23)</li> <li>Zone 2 fitness testing to evaluate mitochondrial performance (1:01:15)</li> <li>Exercise for long-term functional health (1:01:00)</li> <li>Lifestyle changes to improve insulin resistance and other metabolic phenotypes (1:02:55)</li> <li>Aging and leg strength (1:09:59)</li> <li>Ron's approach to exercise and stress management for those with little time (1:10:00)</li> <li>Ron and Peter discuss stress management (1:13:00)</li> <li>Ron discusses his 5S approach to fatigue and stress management (1:16:00)</li> <li>The impact of family dynamics on health risk (1:17:00)</li> <li>PCOS (Polycystic Ovarian Syndrome) and its link to insulin resistance (1:18:34)</li> <li>Stress, adiposity, and weight loss resistance in females(1:20:00)</li> <li>Sleep apnea and insulin resistance (1:29:00)</li> <li>How a culture of achievement and expectations can lead to undue stress, unhappiness, and health problems in our children (a Silicon Valley case study) (1:30:10)</li> <li>The negative impact of devices and social media on children and Ron's approach to managing this (1:40:00)</li> </ul>

<description>&lt;p&gt;Peter was kind enough to allow me to re-release our interview from 2019 from his podcast, The Drive, Episode #69. Many people have found me through Peter and told me this was one of their favorite episodes. Aside from insulin resistance and metabolism, we end the discussion with a topic that really resonated with Peter, which is the impact of generational stress, social media, and devices on youth and how I've navigated this in my own personal life. &lt;/p&gt; &lt;p&gt;This is longer than my usual episodes since we cover a ton of important topics, so I included detailed timestamps below. I hope you enjoy this important conversation. &lt;/p&gt; &lt;ul&gt; &lt;li&gt;Peter's overview and perspective on our discussion (0:58)&lt;/li&gt; &lt;li&gt;Surprise moment for Peter from our discussion (2:30)&lt;/li&gt; &lt;li&gt;How a tough case of insulin resistance led Peter to my work (5:08)&lt;/li&gt; &lt;li&gt;Metabolic disease in South Asian and East Asian patients (5:54)&lt;/li&gt; &lt;li&gt;Triglyceride paradox in African Americans (10:38)&lt;/li&gt; &lt;li&gt;Visceral vs subcutaneous fat and shortcomings of BMI (11:30)&lt;/li&gt; &lt;li&gt;Cortisol and glucose variability (25:00)&lt;/li&gt; &lt;li&gt;Mechanistic discussion of insulin resistance (27:20)&lt;/li&gt; &lt;li&gt;Origins and evolutionary theories on insulin resistance (37:00)&lt;/li&gt; &lt;li&gt;Brown adipose tissue and impact of climate patterns on insulin resistance (46:43)&lt;/li&gt; &lt;li&gt;Vitamin D and hyperinsulinemia (50:38)&lt;/li&gt; &lt;li&gt;Uric acid, high blood pressure, and fructose metabolism(54:05)&lt;/li&gt; &lt;li&gt;VO2 max and Zone 2, including ethnic diferences (56:23)&lt;/li&gt; &lt;li&gt;Zone 2 fitness testing to evaluate mitochondrial performance (1:01:15)&lt;/li&gt; &lt;li&gt;Exercise for long-term functional health (1:01:00)&lt;/li&gt; &lt;li&gt;Lifestyle changes to improve insulin resistance and other metabolic phenotypes (1:02:55)&lt;/li&gt; &lt;li&gt;Aging and leg strength (1:09:59)&lt;/li&gt; &lt;li&gt;Ron's approach to exercise and stress management for those with little time (1:10:00)&lt;/li&gt; &lt;li&gt;Ron and Peter discuss stress management (1:13:00)&lt;/li&gt; &lt;li&gt;Ron discusses his 5S approach to fatigue and stress management (1:16:00)&lt;/li&gt; &lt;li&gt;The impact of family dynamics on health risk (1:17:00)&lt;/li&gt; &lt;li&gt;PCOS (Polycystic Ovarian Syndrome) and its link to insulin resistance (1:18:34)&lt;/li&gt; &lt;li&gt;Stress, adiposity, and weight loss resistance in females(1:20:00)&lt;/li&gt; &lt;li&gt;Sleep apnea and insulin resistance (1:29:00)&lt;/li&gt; &lt;li&gt;How a culture of achievement and expectations can lead to undue stress, unhappiness, and health problems in our children (a Silicon Valley case study) (1:30:10)&lt;/li&gt; &lt;li&gt;The negative impact of devices and social media on children and Ron's approach to managing this (1:40:00)&lt;/li&gt; &lt;/ul&gt;</description>

Peter was kind enough to allow me to re-release our interview from 2019 from his podcast, The Drive, Episode #69. Many people have found me through Peter and told me this was one of their favorite episodes. Aside from insulin resistance and...

#38 - Dr.Peter Attia and I Discuss Insulin Resistance

Is alcohol really a low carb, keto friendly substance like many ads and influencers claim, or is there more to it? Even if the glucose on your CGM (continuous glucose monitor) doesn't budge after a drink, there are real metabolic effects on glucose and body fat you should be aware of. Non-drinkers will benefit from this episode too since we cover some key metabolic principles, along with the following:  <ul> <li>Quick overview of the metabolic merry-go-round and liver metabolism</li> <li>Why your CGM glucose results may be normal or even low after drinking alcohol</li> <li>Pathways by which alcohol affects glucose and body fat</li> <li>The surprising impact of alcohol on muscle </li> <li>How alcohol is disguised and advertised to be "metabolically neutral"</li> <li>My personal approach to alcohol consumption </li> </ul>

<description>&lt;p&gt;Is alcohol really a low carb, keto friendly substance like many ads and influencers claim, or is there more to it? Even if the glucose on your CGM (continuous glucose monitor) doesn't budge after a drink, there are real metabolic effects on glucose and body fat you should be aware of. Non-drinkers will benefit from this episode too since we cover some key metabolic principles, along with the following: &lt;/p&gt; &lt;ul&gt; &lt;li&gt;Quick overview of the metabolic merry-go-round and liver metabolism&lt;/li&gt; &lt;li&gt;Why your CGM glucose results may be normal or even low after drinking alcohol&lt;/li&gt; &lt;li&gt;Pathways by which alcohol affects glucose and body fat&lt;/li&gt; &lt;li&gt;The surprising impact of alcohol on muscle &lt;/li&gt; &lt;li&gt;How alcohol is disguised and advertised to be "metabolically neutral"&lt;/li&gt; &lt;li&gt;My personal approach to alcohol consumption &lt;/li&gt; &lt;/ul&gt;</description>

Is alcohol really a low carb, keto friendly substance like many ads and influencers claim, or is there more to it? Even if the glucose on your CGM (continuous glucose monitor) doesn't budge after a drink, there are real metabolic effects on glucose...

#37 - Alcohol's Real Impact on Body Fat and Glucose

In this episode I answer a question from a listener who is confused regarding whether breakfast is optimal or not optimal for health. Although intermittent fasting made breakfast skipping a common practice, there is nuance to this question. We cover some of the following: <ul> <li>Benefits of breakfast skipping and why it's so common</li> <li>Downsides of breakfast skipping and how it can backfire</li> <li>Why I personally have added breakfast back in on most days</li> <li>Balancing breakfast needs with physical and cognitive demands</li> <li>Optimal breakfast composition</li> <li>Approach to intermittent breakfast skipping </li> </ul>

<description>&lt;p&gt;In this episode I answer a question from a listener who is confused regarding whether breakfast is optimal or not optimal for health. Although intermittent fasting made breakfast skipping a common practice, there is nuance to this question. We cover some of the following:&lt;/p&gt; &lt;ul&gt; &lt;li&gt;Benefits of breakfast skipping and why it's so common&lt;/li&gt; &lt;li&gt;Downsides of breakfast skipping and how it can backfire&lt;/li&gt; &lt;li&gt;Why I personally have added breakfast back in on most days&lt;/li&gt; &lt;li&gt;Balancing breakfast needs with physical and cognitive demands&lt;/li&gt; &lt;li&gt;Optimal breakfast composition&lt;/li&gt; &lt;li&gt;Approach to intermittent breakfast skipping &lt;/li&gt; &lt;/ul&gt;</description>

In this episode I answer a question from a listener who is confused regarding whether breakfast is optimal or not optimal for health. Although intermittent fasting made breakfast skipping a common practice, there is nuance to this question. We cover...

#36 - Is Skipping Breakfast Unhealthy?

Our body has become an obsession that many of us are consumed by day and night. Hollywood and the fashion industry started the movement of creating unrealistic body standards, but now the growing number of celebrity and health influencers have taken this movement and put it on steroids. In this episode I discuss the following: <ul> <li>Reframing the human body so we don't take it so seriously</li> <li>Unrealistic body standards perpetuated by health influencers</li> <li>My own personal challenges with overcoming a Type A approach to health and fitness</li> <li>Putting an end to familial and cultural patterns of body shaming</li> <li>The disturbing impact of social media and AI filters</li> <li>Why body composition scans can be a problem</li> <li>Strategies for detaching from body/fitness/health/longevity obsession, including a visualization exercise</li> </ul>

<description>&lt;p&gt;Our body has become an obsession that many of us are consumed by day and night. Hollywood and the fashion industry started the movement of creating unrealistic body standards, but now the growing number of celebrity and health influencers have taken this movement and put it on steroids. In this episode I discuss the following:&lt;/p&gt; &lt;ul&gt; &lt;li&gt;Reframing the human body so we don't take it so seriously&lt;/li&gt; &lt;li&gt;Unrealistic body standards perpetuated by health influencers&lt;/li&gt; &lt;li&gt;My own personal challenges with overcoming a Type A approach to health and fitness&lt;/li&gt; &lt;li&gt;Putting an end to familial and cultural patterns of body shaming&lt;/li&gt; &lt;li&gt;The disturbing impact of social media and AI filters&lt;/li&gt; &lt;li&gt;Why body composition scans can be a problem&lt;/li&gt; &lt;li&gt;Strategies for detaching from body/fitness/health/longevity obsession, including a visualization exercise&lt;/li&gt; &lt;/ul&gt;</description>

Our body has become an obsession that many of us are consumed by day and night. Hollywood and the fashion industry started the movement of creating unrealistic body standards, but now the growing number of celebrity and health influencers have taken...

#35 - Your Body Is A Problem

Eating more protein is currently the mantra being shared by many health leaders and big food has caught on. Are we missing any potential risks in the midst of the high protein movement? This episode covers some of the following topics: <ul> <li>Lessons learned from the low fat, low carb, and fasting movements</li> <li>How higher protein diets are being misused by many</li> <li>Understanding the important mismatch between protein intake and energy expenditure</li> <li>What happens to excess protein in the body?</li> <li>Finding the goldilocks zone for mTOR activation</li> <li>Protein intake recommendations for different groups</li> </ul>

<description>&lt;p&gt;Eating more protein is currently the mantra being shared by many health leaders and big food has caught on. Are we missing any potential risks in the midst of the high protein movement? This episode covers some of the following topics:&lt;/p&gt; &lt;ul&gt; &lt;li&gt;Lessons learned from the low fat, low carb, and fasting movements&lt;/li&gt; &lt;li&gt;How higher protein diets are being misused by many&lt;/li&gt; &lt;li&gt;Understanding the important mismatch between protein intake and energy expenditure&lt;/li&gt; &lt;li&gt;What happens to excess protein in the body?&lt;/li&gt; &lt;li&gt;Finding the goldilocks zone for mTOR activation&lt;/li&gt; &lt;li&gt;Protein intake recommendations for different groups&lt;/li&gt; &lt;/ul&gt;</description>

Eating more protein is currently the mantra being shared by many health leaders and big food has caught on. Are we missing any potential risks in the midst of the high protein movement? This episode covers some of the following topics:  Lessons...

#34 - Are We Taking Higher Protein Diets Too Far?

The Meta Health podcast simplifies the science of health, nutrition and metabolism by sparking your imagination through creative storytelling and visualization.  You'll gain a deep understanding of your body to help you make informed and personalized lifestyle choices. 

The host, Dr.Ronesh Sinha, is a physician, author, speaker, and teacher who runs a lifestyle clinic focused on reversing insulin resistance in diverse ethnic groups, and designs wellness programs for top Silicon Valley companies.

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