Plain English with Derek Thompson

For years, scientists worried that medical progress was slowing down. Drug development became more expensive than ever with more complex clinical trials, and even then, many new treatments offered only modest gains. But over the past month, a series of breakthroughs has raised hopes that medicine may be entering a new era. Researchers unveiled a massively promising new therapy for pancreatic cancer, a gene-editing treatment that could dramatically reduce the risk of heart disease, and an experimental obesity drug that not only produces unprecedented weight loss but also improves a huge range of related conditions. Cancer and heart disease are America’s two biggest killers, but if these treatments fulfill their promise, they could transform public health and extend millions of lives. Today’s guest is Matthew Herper, senior writer at STAT News. We discuss this remarkable month in medicine, why so many advances are arriving at once, and what they could mean for the future of human health. Subscribe to our YouTube channel here:https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at [email protected]. Host: Derek ThompsonGuest: Matthew HerperProducer: Devon BaroldiAdditional Production Support: Ben Glicksman All Matches Streaming Live. Watch 3 Days Free. Offers are subject to change. See fox.com for complete terms and conditions. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Prior to the 1930s, old age in America often meant poverty. But thanks to Social Security, Medicare, medical advances, and rising asset prices, over the past 90 years, older Americans have become one of the wealthiest and most politically powerful groups in the country. In his new book, 'Gerontocracy in America,' Samuel Moyn argues that this success has created a dangerous imbalance. He says America isn't just facing oligarchy, or rule by the rich, but "Old-igarchy": a system in which wealth and power are increasingly concentrated among older generations, often at the expense of younger Americans. Today, Derek talks with Moyn about the rise of gerontocracy in America, whether elderly power has become a problem, what reforms could rebalance the scales between generations, and whether this argument is a serious critique of American politics or simply ageist nonsense. Subscribe to our YouTube channel here:https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at [email protected]. Host: Derek ThompsonGuest: Samuel MoynProducer: Devon BaroldiAdditional Production Support: Ben Glicksman Learn more about your ad choices. Visit podcastchoices.com/adchoices

Humans are unusual dads. Across the animal kingdom, dads are often absent from child-rearing altogether. But among humans, fatherhood takes many forms, and in the last half century, it has changed dramatically. College-educated American fathers now spend nearly four times as much time caring for their children as they did in the 1960s. And according to new research, this new type of fatherhood doesn't just change a man's schedule or priorities—it can literally change his brain. Today, Derek talks with USC psychologist Darby Saxbe, author of 'Dad Brain,' about the science of modern fatherhood. They discuss how active parenting affects men's psychology and how changing expectations around fatherhood are reshaping families and men themselves. Subscribe to our YouTube channel here:https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at [email protected]. Host: Derek ThompsonGuest: Darby SaxbeProducer: Devon BaroldiAdditional Production Support: Ben Glicksman Learn more about your ad choices. Visit podcastchoices.com/adchoices

For generations, we've defined creativity by its products: the novel, the painting, the song, the breakthrough idea. We look at the work, and from the work we see the creator as “creative.” But AI is getting remarkably good at producing creative work. In some cases, experts now prefer AI-generated writing to work created by humans and can't reliably tell the difference between the two. In fact, a major literary prize even recently honored a work that was largely written by AI. It all raises a deeper question than whether or not AI can write well. It forces us to reconsider what creativity actually is. Today, neuroscientist Adam Green joins the show to discuss how AI is changing the way we write, think, and generate ideas. His research finds that while AI can make our language more polished and sophisticated, it may also make our thinking more uniform. The sentences get sharper. The ideas get more predictable. And If creativity is no longer something we can recognize from the final product alone, we may need a new, more human definition. Subscribe to our YouTube channel here:https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at [email protected]. Host: Derek ThompsonGuest: Dr. Adam GreenProducer: Devon BaroldiAdditional Production Support: Ben Glicksman Learn more about your ad choices. Visit podcastchoices.com/adchoices

Modern loneliness is often treated as a simple problem: People are simply spending more time alone. But what if that's not the whole story? Over the last several years, Derek has written about workism, the rise of a culture that puts work at the center of our lives, and the "antisocial century," in which technology has made it easier than ever to avoid spending time with other people. The result is a world where many of us trade deep connection for convenience, productivity, and fleeting hits of entertainment. Today, Derek talks with Yale psychology professor and Happiness Lab host Laurie Santos about the science of friendship, connection, and loneliness. What do we misunderstand about being alone? Why are male friendships harder to maintain? And how can we build stronger relationships in a world that seems designed to pull us apart? Subscribe to our YouTube channel here:https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at [email protected]. Host: Derek Thompson Guest: Laurie Santos Producer: Devon Baroldi Additional Production Support: Ben Glicksman Learn more about your ad choices. Visit podcastchoices.com/adchoices