Explore ESC 25 Top Trials with Insights from the Thoraxcenter! Join Prof Nicolas Van Mieghem and Dr Joost Daemen from Erasmus MC, Rotterdam, for an engaging and critical analysis of the latest trials unveiled at ESC 2025. In this comprehensive ESC wrap-up, interventional experts examine the most significant trials, providing valuable insights into their impact on current practices and future research directions. 00:15 - DOUBLE-CHOICE 04:43 - VANTAGE 07:44 - VICTOR and VICTORIA 11:29 - DIGIT-HF 14:22 - DAPA ACT HF-TIMI 68 16:55 - BETAMI-DANBLOCK and REBOOT-CNIC 22:13 - REFINE-ICD 25:34 - OPTION-STEMI 30:40 - DUAL-ACS 33:05 - NEO-MINDSET 35:58 - TARGET-FIRST 38:54 - OUTREACH 41:50 - FIRE 42:46 - AI-Gatekeeper 45:13 - POTCAST