Soul & Science: Fast Forward Your Marketing Mind

How does a brand stay culturally relevant across 200 countries? This week on Soul & Science, Jason Harris talks to Rustom Dastoor, EVP and Head of Marketing & Communications at Mastercard, about building a brand that resonates across cultures, markets, and generations. Born and raised in India amid the country’s surge towards consumerism, Rustom has lived and worked across four continents and brings a uniquely international perspective to branding, consumer behavior, and the evolving relationship between creativity and technology. Rustom shares how Mastercard balances global consistency with local relevance across hundreds of markets, the growing importance of regulation and data governance, and why the best brands integrate into local culture instead of simply extracting value from it. They also discuss the future of marketing, why successful marketing will increasingly need to put data at the center of strategy, and why AI and data are most powerful when they’re used to guide thinking—not replace it. Key Takeaways ✅ Global brands succeed when they integrate into local culture ✅ Data should inform decisions, not dictate them ✅ AI adds real value in data analysis, not automation ✅ Consistency builds trust, but relevance drives connection Memorable Moments 💡 “To gain something new, you have to give up something old.” 💡 “People are more similar than they are different.” 💡 “Use data for illumination, not support.” 💡 “If you’re comfortable, you’re stagnating.” 💡 “A global brand needs to be seen as a contributor, not an extractor.” Brought to you by Mekanism.

How do you make a digital marketplace feel human? This week on Soul & Science, Jason Harris talks to Llibert Argerich, CMO of Thumbtack, about the unique challenges of marketplace marketing and why trust can’t just be built through brand—it has to be built into the platform itself. From Expedia to eBay, Llibert has spent his career building businesses that connect people through technology and studying both the supply and demand sides of the marketplace. Llibert shares how Thumbtack approaches marketing as a profit center tied directly to business growth, the challenge of scaling hyperlocal trust between homeowners and maintenance professionals to a national market, and how AI is improving the platform’s matching engine. They also discuss why differentiating “brand” and “performance” marketing is counterproductive, the critical role of data in successful outcomes, and why the strongest marketplace brands are built through consistent customer experience. Key Takeaways ✅ Build trust into the product—not just the brand ✅ Successful marketplace marketing considers both supply and demand ✅ Brand and performance marketing are intertwined ✅ CMOs must be able to speak the same language as CEOs & CFOs ✅ Hyperlocal marketplaces require hyperlocal thinking at scale Memorable Moments 💡 “Marketing is not a cost center, it’s a profit center.” 💡 “The brand is the product, and the product is the brand.” 💡 “Awareness is not a business metric.” 💡 “Every ad must both build the brand and drive performance.” 💡 “There’s no manual that comes with buying a home.” Brought to you by Mekanism.

Most marketers see AI as a tool. What if it’s also the audience? This week on Soul & Science, Jason Harris sits down with Chris Koehler, CMO of Twilio, to discuss B2B marketing and how AI is fundamentally changing the way brands communicate with consumers. From a 10-year stint at Adobe to navigating AI adoption at Box and now Twillo, Chris brings a deep understanding of how technology transforms both marketing strategy and customer behavior. Chris shares how Twilio is rethinking marketing from the inside out, from creating dedicated AI innovation roles to rebuilding workflows around speed, experimentation, and parallel collaboration. He explains how AI is changing discovery as consumers shift from search engines to AI agents—and why marketers now need to optimize for both humans and machines. They also discuss the increasing importance of brand awareness, the evolving roles of specialists and generalists, and why less is more in a market oversaturated with AI-generated content. Key Takeaways ✅ AI is both tool and a means of discovery ✅ Generalists work faster, but specialists are the gut-check ✅ Brands awareness is critical in an AI-driven world ✅ Adapting to AI means rethinking entire workflows ✅ The future of marketing is knowing how to say less Memorable Moments 💡 “B2B doesn’t have to suck.” 💡 “Everyone wants to feel like they’re building something.” 💡 “Content used to be the bottleneck; now it’s ubiquitous.” 💡 “How do you convince AI agents to recommend your brand to humans?” 💡 “The best teams are the ones brave enough to say less.” Brought to you by Mekanism.

What does it take to turn a legacy brand into something bigger? This week on Soul & Science, Jason Harris sits down with Victoria Lozano, former CMO and EVP at Crayola, to discuss how she helped evolve one of the world’s most recognizable brands into a multi-platform growth engine. Drawing on her experience in both marketing and finance, Victoria’s approach ties brand strategy directly to business results. In their conversation, Victoria shares how redefining Crayola as a “creativity brand” unlocked new revenue streams, from in-person attractions to entertainment and digital platforms. She explains why the most effective brands know what they stand for: they’re built on clear, simple ideas that extend beyond a single product. They also discuss the realities of modern marketing, from navigating ambiguity and complexity to managing large teams that can execute with both creativity and discipline. Key Takeaways ✅ Knowing what your brand stands for can unlock growth ✅ Successful ideas need time, iteration, and refinement ✅ Simplicity makes it easier to understand and execute the vision ✅ Focusing on what matters most increases your chances of success ✅ Innovation isn’t just products; it’s how the business evolves Memorable Moments 💡 “Don’t get distracted by shiny objects.” 💡 “What difference do you make in their life?” 💡 “There’s no business you’ll ever be in where you don’t fail.” 💡 “Most successful businesses take a little bit of nurturing.” 💡 “You have to be comfortable living with ambiguity.” Brought to you by Mekanism.

What if your last idea was the one that mattered most? This week on Soul & Science, Jason Harris sits down with Mekanism alums Tony Benna and Lee Einhorn, the director and producer behind André Is an Idiot: a documentary that follows their friend André Ricciardi as he faces stage four colon cancer with a sense of humor. What began as an outrageous pitch from André—that if he was going to die, they should film it—became a three-and-a-half-year journey documenting the final years of his life through laughter, tears, and honest, irreverent storytelling. Tony and Lee share how the film came together, the challenge of balancing comedy and grief, and why staying true to André’s voice meant refusing to make the “sad cancer film” the world expected. They also look back on the film’s whirlwind path to success, from getting picked up by A24 to winning the Audience Award at Sundance and finally securing distribution, and how it has evolved into something more than just a documentary: it’s sparking conversations, encouraging people to get screened for cancer, and ultimately saving lives. Key Takeaways ✅ Humor can help us face the hardest truths ✅ Being invited in is an honor and a responsibility ✅ Sharing your story can make a difference ✅ Always stay true to your voice ✅ Great stories start with real relationships Memorable Moments 💡 “To be invited into those last years of his life was a huge honor.” 💡 “André’s like, ‘I’ve got stage four cancer, let’s make a comedy." 💡 “The bigger goal the whole time was to save lives.” 💡 “It was one of the best times of my life, as horrible as that sounds.” 💡 “Laughter was the best medicine—not just for André, but for all of us” Brought to you by Mekanism.