AI For Pharma Growth

Designing proteins that have never existed in nature is no longer sci-fi — it’s becoming a real drug discovery strategy. In this episode, Kashif Sadiq, Founder & CEO of DenovAI Biotech, explains how AI is powering a shift from searching for biologic binders to intentionally designing new proteins from scratch.Kashif shares his journey from studying physics at University of Cambridge into computational biophysics, and how breakthroughs like AlphaFold from DeepMind helped unlock the next frontier: de novo protein design. Instead of hoping evolution has already produced a usable molecule, Kashif describes how modern AI can engineer bespoke proteins for specific functions, including challenging targets where traditional approaches come up short.The conversation dives into the sheer scale of “protein space” and why evolution has only explored a tiny fraction of what’s possible. Kashif outlines how this opens the door to targeting diseases and biological mechanisms that have historically been considered undruggable, especially where flat protein interfaces or complex signalling pathways have made small molecules ineffective.Finally, Kashif explains why combining generative AI with physics-based methods is essential to reduce false positives, improve real-world binding performance, and enable “one-shot design” — where discovery and optimisation become a single integrated process. He also shares what keeps him up at night: clinical trial attrition — and why designing better earlier may be the key to improving success later.Topics CoveredDe novo protein design vs traditional biologics discoveryWhy evolution explored only a tiny fraction of protein space“Programmable biologics” and intentional molecular designAlpha Design and designing proteins from the inverse problemAntibodies, nanobodies, and therapeutic protein engineeringCombining generative AI with physics-based validationReducing false positives in protein binding predictions“One-shot design” and compressing discovery timelinesUndruggable targets, flat interfaces, and intracellular signallingClinical trial attrition and what’s missing at the preclinical stageWhen the first de novo-designed therapeutic could enter trialsAbout the PodcastAI for Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr Andree Bates, created to help pharma, biotech and healthcare organisations understand how AI-based technologies can save time, grow brands, and improve company results.This show blends deep sector experience with practical, no-fluff conversations that demystify AI for biopharma execs — from start-up biotech right through to Big Pharma. Each episode features experts building AI-powered tools that are driving real-world results across discovery, R&D, clinical trials, market access, medical affairs, regulatory, insights, sales, marketing, and more.Dr. Andree Bates LinkedIn | Facebook | X

Large Language Models (LLMs) are moving far beyond text generation—and into the heart of scientific discovery and pharmaceutical research. In this episode, Javier Tordable, founder and CEO of Pauling.ai and former Google technologist, explains how agentic AI systems are transforming early-stage drug discovery.Javier shares how modern LLMs differ from earlier generations, highlighting their ability to perform autonomous, multi-step scientific workflows rather than isolated tasks. These AI agents can read and synthesize massive volumes of scientific literature, generate novel hypotheses, validate ideas against published research, and accelerate computational chemistry simulations that once took months or years.The discussion dives into how LLMs are being used today to identify drug targets, design molecules, optimize clinical trials, and reduce manual scientific labor, while still preserving the critical role of human creativity and experimental validation. Javier also addresses the real risks—hallucinations, data quality, reproducibility—and why hybrid AI + physics-based approaches are essential for trustworthy results.This episode is a must-listen for researchers, founders, and operators exploring LLMs in biotech, pharma AI, scientific automation, and computational drug discovery.Topics CoveredLarge Language Models (LLMs) in science and pharmaAI agents and autonomous research workflowsEarly-stage drug discovery accelerationComputational chemistry and molecular simulationsAI-assisted literature review and hypothesis generationClinical trial optimization with AIReducing R&D timelines and operational bottlenecksRisks, hallucinations, and validation in scientific AIAbout the PodcastAI for Pharma Growth is a podcast focused on exploring how artificial intelligence can revolutionise healthcare by addressing disparities and creating equitable systems. Join us as we unpack groundbreaking technologies, real-world applications, and expert insights to inspire a healthier, more equitable future.This show brings together leading experts and changemakers to demystify AI and show how it’s being used to transform healthcare. Whether you're in the medical field, technology sector, or just curious about AI’s role in social good, this podcast offers valuable insights.AI For Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr. Andree Bates created to help organisations understand how the use of AI based technologies can easily save them time and grow their brands and business. This show blends deep experience in the sector with demystifying AI for all pharma people, from start up biotech right through to Big Pharma. In this podcast Dr Andree will teach you the tried and true secrets to building a pharma company using AI that anyone can use, at any budget.As the author of many peer-reviewed journals and having addressed over 500 industry conferences across the globe, Dr Andree Bates uses her obsession with all things AI and futuretech to help you to navigate through the, sometimes confusing but, magical world of AI powered tools to grow pharma businesses.This podcast features many experts who have developed powerful AI powered tools that are the secret behind some time saving and supercharged revenue generating business results. Those who share their stories and expertise show how AI can be applied to sales, marketing, production, social media, psychology, customer insights and so much more.Dr. Andree Bates LinkedIn | Facebook | Twitter

Artificial intelligence is rapidly reshaping the pharmaceutical industry—and nowhere is that more evident than in small-molecule drug discovery. In this episode, we sit down with Tom Shani, CEO and co-founder of ProPhet, an AI-driven biotech company focused on discovering drugs for hard-to-target proteins.Tom explains how machine learning models, transformers, and AI-driven molecular representations are overcoming the biggest limitations of traditional drug discovery: slow timelines, high failure rates, missing data, and billion-dollar R&D costs. Rather than relying solely on physics-based simulations and trial-and-error lab work, AI systems learn patterns directly from noisy biological data—making them uniquely suited for real-world biology.The conversation explores how AI can compress drug discovery timelines from decades to years, reduce failed trials, and dramatically lower costs by improving early-stage target and molecule selection. Tom also breaks down why small molecules remain the backbone of modern medicine, how AI enables scalable exploration of vast chemical space, and why trust, regulation, and validation remain the biggest hurdles to adoption.This episode is essential listening for anyone working in pharma R&D, biotech, AI-driven drug discovery, computational biology, or life sciences innovation.Topics CoveredAI-powered small-molecule drug discoveryMachine learning vs traditional pharmaceutical R&DHard-to-drug proteins and undruggable targetsTransformers, AlphaFold, and molecular representationsReducing drug discovery timelines and costsAI robustness to missing and noisy biological dataOff-target effects, toxicity, and safety predictionThe future of AI in pharma and biotech startupsAbout the PodcastAI for Pharma Growth is a podcast focused on exploring how artificial intelligence can revolutionise healthcare by addressing disparities and creating equitable systems. Join us as we unpack groundbreaking technologies, real-world applications, and expert insights to inspire a healthier, more equitable future.This show brings together leading experts and changemakers to demystify AI and show how it’s being used to transform healthcare. Whether you're in the medical field, technology sector, or just curious about AI’s role in social good, this podcast offers valuable insights.AI For Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr. Andree Bates created to help organisations understand how the use of AI based technologies can easily save them time and grow their brands and business. This show blends deep experience in the sector with demystifying AI for all pharma people, from start up biotech right through to Big Pharma. In this podcast Dr Andree will teach you the tried and true secrets to building a pharma company using AI that anyone can use, at any budget.As the author of many peer-reviewed journals and having addressed over 500 industry conferences across the globe, Dr Andree Bates uses her obsession with all things AI and futuretech to help you to navigate through the, sometimes confusing but, magical world of AI powered tools to grow pharma businesses.This podcast features many experts who have developed powerful AI powered tools that are the secret behind some time saving and supercharged revenue generating business results. Those who share their stories and expertise show how AI can be applied to sales, marketing, production, social media, psychology, customer insights and so much more.Dr. Andree Bates LinkedIn | Facebook | Twitter

In this episode, Dr. Andre Bates, Founder & CEO of Eularis, joins Cures and Capital hosts Martin and Simona to explore how artificial intelligence is transforming drug discovery, R&D productivity, and enterprise strategy across the biopharma industry.Dr. Andre Bates shares a pragmatic view on AI in the biopharma industry, cutting through the hype to explore where AI is already delivering value and where companies need to focus for real impact. From regulatory document preparation to AI-driven drug discovery, Andre explains how AI is transforming the industry—and why human adoption is just as critical as the technology itself.What You’ll Learn from This Episode:The “low-hanging fruit” for AI in pharma, including regulatory, clinical, and medical affairs applications.How AI is accelerating drug discovery, clinical trials, and predictive healthcare.The importance of human trust and adoption in successful AI implementation.Predictions for AI-driven transformations in business models, digital twins, and disease prevention.Practical steps for building a disciplined AI strategy with measurable ROI.About the PodcastAI for Pharma Growth is a podcast focused on exploring how artificial intelligence can revolutionise healthcare by addressing disparities and creating equitable systems. Join us as we unpack groundbreaking technologies, real-world applications, and expert insights to inspire a healthier, more equitable future.This show brings together leading experts and changemakers to demystify AI and show how it’s being used to transform healthcare. Whether you're in the medical field, technology sector, or just curious about AI’s role in social good, this podcast offers valuable insights.AI For Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr. Andree Bates created to help organisations understand how the use of AI based technologies can easily save them time and grow their brands and business. This show blends deep experience in the sector with demystifying AI for all pharma people, from start up biotech right through to Big Pharma. In this podcast Dr Andree will teach you the tried and true secrets to building a pharma company using AI that anyone can use, at any budget. As the author of many peer-reviewed journals and having addressed over 500 industry conferences across the globe, Dr Andree Bates uses her obsession with all things AI and futuretech to help you to navigate through the, sometimes confusing but, magical world of AI powered tools to grow pharma businesses. This podcast features many experts who have developed powerful AI powered tools that are the secret behind some time saving and supercharged revenue generating business results. Those who share their stories and expertise show how AI can be applied to sales, marketing, production, social media, psychology, customer insights and so much more. Dr. Andree Bates LinkedIn | Facebook | Twitter

In this episode, Dr. Andre Bates, Founder & CEO of Eularis, joins Cures and Capital hosts Martin and Simona to explore how artificial intelligence is transforming drug discovery, R&D productivity, and enterprise strategy across the biopharma industry.Dr. Bates shares actionable insights into the real-world potential of AI to reduce time-to-market, cut development costs, and create competitive advantage. From AI strategy alignment with business goals to executive board responsibilities and data governance, this episode dives deep into what it takes to implement AI successfully across the pharmaceutical value chain.What You’ll Learn in This Episode:How AI can accelerate drug discovery and clinical trials, potentially reducing costs and time-to-market by up to 50–60%.Why many pharma companies are struggling to convert AI pilots into measurable business outcomes.The importance of connecting AI initiatives to strategic business objectives, rather than treating them as isolated tech projects.Key roles for the CEO, CFO, R&D leaders, and board directors in driving enterprise-wide AI adoption.How to identify "pockets of excellence" in AI implementation and the path to fully integrated AI in pharma.Practical guidance on leveraging company data for AI while avoiding common pitfalls.Emerging trends like digital twins, synthetic data, and multimodal AI for the life sciences sector.Whether you’re a pharma executive, AI strategist, or R&D professional, this episode provides a comprehensive roadmap to harness AI for sustainable innovation and measurable ROI in biopharma.About the PodcastAI for Pharma Growth is a podcast focused on exploring how artificial intelligence can revolutionise healthcare by addressing disparities and creating equitable systems. Join us as we unpack groundbreaking technologies, real-world applications, and expert insights to inspire a healthier, more equitable future.This show brings together leading experts and changemakers to demystify AI and show how it’s being used to transform healthcare. Whether you're in the medical field, technology sector, or just curious about AI’s role in social good, this podcast offers valuable insights.AI For Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr. Andree Bates created to help organisations understand how the use of AI based technologies can easily save them time and grow their brands and business. This show blends deep experience in the sector with demystifying AI for all pharma people, from start up biotech right through to Big Pharma. In this podcast Dr Andree will teach you the tried and true secrets to building a pharma company using AI that anyone can use, at any budget. As the author of many peer-reviewed journals and having addressed over 500 industry conferences across the globe, Dr Andree Bates uses her obsession with all things AI and futuretech to help you to navigate through the, sometimes confusing but, magical world of AI powered tools to grow pharma businesses. This podcast features many experts who have developed powerful AI powered tools that are the secret behind some time saving and supercharged revenue generating business results. Those who share their stories and expertise show how AI can be applied to sales, marketing, production, social media, psychology, customer insights and so much more. Dr. Andree Bates LinkedIn | Facebook | Twitter