Medscape InDiscussion: Psoriasis

Drs Steven Feldman and Tina Bhutani-Jacques explore how next-generation oral therapies are closing the gap with biologics and reshaping psoriasis care. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-psoriasis-s4-ep2-2026a10006a5. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Acitretin Revisited in the Era of Biologics https://pubmed.ncbi.nlm.nih.gov/20673152/ Apremilast in Psoriasis: Current Landscape and Perspectives https://pubmed.ncbi.nlm.nih.gov/40739686/ Deucravacitinib Versus Placebo and Apremilast in Moderate-to-Severe Plaque Psoriasis: Efficacy and Safety Results From the 52-Week, Randomized, Double-Blinded, Placebo-Controlled Phase 3 POETYK PSO-1 Trial https://pubmed.ncbi.nlm.nih.gov/35820547/ Apremilast Prescribing Information https://www.pi.amgen.com/-/media/Project/Amgen/Repository/pi-amgen-com/Otezla/otezla_pi_english.pdf Deucravacitinib Prescribing Information https://packageinserts.bms.com/pi/pi_sotyktu.pdf Tyrosine Kinase 2 Inhibition With Zasocitinib (TAK-279) in Psoriasis: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/39167366/ Emerging Oral Therapies for the Treatment of Psoriasis: A Review of Pipeline Agents https://pubmed.ncbi.nlm.nih.gov/38258121/ Oral Icotrokinra for Plaque Psoriasis in Adults and Adolescents https://pubmed.ncbi.nlm.nih.gov/41191940/ National Psoriasis Foundation https://www.psoriasis.org/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Join Drs Steven Feldman and Bernard Vrijens as they discuss the theory and practice of improving treatment adherence for better patient outcomes in psoriasis. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-psoriasis-s4-ep1-2026a10006a1. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.   Resources Psoriasis https://emedicine.medscape.com/article/1943419-overview The Importance of Assessing Drug Exposure and Medication Adherence in Evaluating Investigational Medications: Ensuring Validity and Reliability of Clinical Trial Results https://pubmed.ncbi.nlm.nih.gov/38135800/ Comparing Compliance Patterns Between Randomized Treatments https://pubmed.ncbi.nlm.nih.gov/9204220/ A Scoping Review of Studies Comparing the Medication Event Monitoring System (MEMS) With Alternative Methods for Measuring Medication Adherence https://pubmed.ncbi.nlm.nih.gov/27005306/ A New Taxonomy for Describing and Defining Adherence to Medications https://pubmed.ncbi.nlm.nih.gov/22486599/ One in 3 Prescriptions Are Never Redeemed: Primary Nonadherence in an Outpatient Clinic https://pubmed.ncbi.nlm.nih.gov/18467003/ Data Resource Profile: The Danish National Prescription Registry https://pubmed.ncbi.nlm.nih.gov/27789670/ Tachyphylaxis to Topical Glucocorticoids; What Is the Evidence? https://pubmed.ncbi.nlm.nih.gov/24010503/ Emerging Oral Therapies for the Treatment of Psoriasis: A Review of Pipeline Agents https://pubmed.ncbi.nlm.nih.gov/38258121/ 10 Tips to Improve Adherence to Immunosuppressive Medication After Kidney Transplantation https://pubmed.ncbi.nlm.nih.gov/40521289/ The Health Buddies App as a Novel Tool to Improve Adherence and Knowledge in Atrial Fibrillation Patients: A Pilot Study https://pubmed.ncbi.nlm.nih.gov/28724512/ 6MP Adherence in a Multiracial Cohort of Children With Acute Lymphoblastic Leukemia: A Children's Oncology Group Study https://pubmed.ncbi.nlm.nih.gov/24829202/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

From polyaphron technology to fixed combinations, new formulations improve tolerability, adherence, and patient satisfaction. Join Drs Feldman and Armstrong as they discuss. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002116. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Psoriasis https://emedicine.medscape.com/article/1943419-overview expertscape https://expertscape.com/ PDE4 Inhibitors: Bridging Molecular Insights With Clinical Impact https://pubmed.ncbi.nlm.nih.gov/40465498/ Topical Corticosteroids https://www.ncbi.nlm.nih.gov/books/NBK532940/ Psoriasis Clinical Guideline https://www.aad.org/member/clinical-quality/guidelines/psoriasis Psoriasis Area Severity Index (PASI) and the Dermatology Life Quality Index (DLQI): The Correlation Between Disease Severity and Psychological Burden in Patients Treated With Biological Therapies https://pubmed.ncbi.nlm.nih.gov/23425140/ Keratosis Pilaris https://emedicine.medscape.com/article/1070651-overview Review of the Mechanism of Action of Coal Tar in Psoriasis https://pubmed.ncbi.nlm.nih.gov/28814117/ Treatment Adherence Intervention Studies in Dermatology and Guidance on How to Support Adherence https://pubmed.ncbi.nlm.nih.gov/28188596/ Polyaphron Dispersion Technology, a Novel Topical Formulation and Delivery System Combining Drug Penetration, Local Tolerability and Convenience of Application https://pubmed.ncbi.nlm.nih.gov/36050567/ Fixed-Combination Halobetasol Propionate and Tazarotene in the Treatment of Psoriasis: Narrative Review of Mechanisms of Action and Therapeutic Benefits https://pubmed.ncbi.nlm.nih.gov/34106439/

From polyaphron technology to fixed combinations, new formulations improve tolerability, adherence, and patient satisfaction. Join Drs Feldman and Armstrong as they discuss. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-psoriasis-s3-ep6-2026a100069z. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Psoriasis https://emedicine.medscape.com/article/1943419-overview expertscape https://expertscape.com/ PDE4 Inhibitors: Bridging Molecular Insights With Clinical Impact https://pubmed.ncbi.nlm.nih.gov/40465498/ Topical Corticosteroids https://www.ncbi.nlm.nih.gov/books/NBK532940/ Psoriasis Clinical Guideline https://www.aad.org/member/clinical-quality/guidelines/psoriasis Psoriasis Area Severity Index (PASI) and the Dermatology Life Quality Index (DLQI): The Correlation Between Disease Severity and Psychological Burden in Patients Treated With Biological Therapies https://pubmed.ncbi.nlm.nih.gov/23425140/ Keratosis Pilaris https://emedicine.medscape.com/article/1070651-overview Review of the Mechanism of Action of Coal Tar in Psoriasis https://pubmed.ncbi.nlm.nih.gov/28814117/ Treatment Adherence Intervention Studies in Dermatology and Guidance on How to Support Adherence https://pubmed.ncbi.nlm.nih.gov/28188596/ Polyaphron Dispersion Technology, a Novel Topical Formulation and Delivery System Combining Drug Penetration, Local Tolerability and Convenience of Application https://pubmed.ncbi.nlm.nih.gov/36050567/ Fixed-Combination Halobetasol Propionate and Tazarotene in the Treatment of Psoriasis: Narrative Review of Mechanisms of Action and Therapeutic Benefits https://pubmed.ncbi.nlm.nih.gov/34106439/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Join Drs Steve Feldman and Alexis Ogdie as they explore digital tools that detect and monitor psoriasis and psoriatic arthritis — using only a smartphone, movement, and a few taps. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002115. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Clinical Validation of Digitally Acquired Clinical Data and Machine Learning Models for Remote Measurement of Psoriasis and Psoriatic Arthritis: A Proof-of-Concept Study https://pubmed.ncbi.nlm.nih.gov/38879192/ Psorcast https://apps.apple.com/us/app/psorcast/id1473504102 Psoriasis and Psoriatic Arthritis Clinics Multicenter Advancement Network Consortium (PPACMAN) 2021 Annual Meeting Proceedings https://pubmed.ncbi.nlm.nih.gov/39301469/ Sleep Problems in Patients With Psoriatic Arthritis: A Systematic Literature Review and Metaanalysis https://pubmed.ncbi.nlm.nih.gov/37127321/ The Impact of Dietary Interventions in Psoriatic Arthritis https://pubmed.ncbi.nlm.nih.gov/37339523/