The Dr. Gabrielle Lyon Show

Metabolic flexibility is your body’s ability to efficiently burn fat or carbohydrate depending on demand, may be one of the most important and least understood markers of long-term health. In this episode, I’m with Dr. Martin Gibala to explore the emerging science of Fat Max, why mitochondrial quality is central to both performance and longevity, and how sprint interval training produces comparable mitochondrial adaptations to traditional endurance work in a fraction of the time. Could the key to better metabolic health be less about the hours you log and more about how hard you’re willing to push?Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSReGet Dr. Martin Gibala’s book, “The One-Minute Workout” here: https://bit.ly/4lxBchqConnect with Dr. Martin GibalaWebsite: https://bit.ly/3P8ROjdWebsite: https://bit.ly/3Nfz410Instagram: https://bit.ly/40qrVhlX.com: https://bit.ly/4b9usCPYouTube: https://bit.ly/3PiVkYhEmail: [email protected]🙌Thank you to our sponsors:🛌 Cozy Earth - Go to https://bit.ly/4loRB7A for up to 20% off!🚴 Carol Bike - Visit https://bit.ly/4b9KFYF and use code LYON for $100 off your CAROL Bike☕ Four Sigmatic - Go to https://bit.ly/4lp0Ep2 for a free bag of their dark roast ground coffee (just pay for shipping & handling).📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:YouTube: https://bit.ly/4boCFC3Spotify: https://bit.ly/4cWTbLG📱Connect with Dr. Gabrielle Lyon:Instagram: https://bit.ly/4uk9adcTikTok: https://bit.ly/3OFK3kJX.com: https://bit.ly/4l3YlaXFacebook: https://bit.ly/3MBrJsoLinkedIn: https://bit.ly/3N1nrdLWebsite: https://bit.ly/3NdV2kTBooks: https://bit.ly/4r6ugZKNewsletter: https://bit.ly/402QCAj⏰Timestamps:00:00 Intro of Show01:26 What is High-Intensity Interval Training?05:04 HIIT to Improve Health Fundamentally08:23 Exercise Ratio for General Individuals vs. Athletes14:29 Dr. Lyon's Workout Routine16:47 High-Intensity Interval vs. Sprint Interval Training20:23 New Studies on Sprint Interval Training24:57 The One-Minute Workout26:57 CAROL Bike Mechanics28:59 Benefits of High-Intensity Interval Training37:21 Fuel Utilization: Sprint Interval vs. Slow, Steady-State Training45:38 Metabolic Flexibility Definition46:41 Fat Max Definition and Evaluation50:26 Zone Training Model58:00 Designing the Health of the Nation1:04:04 How to Improve Body Composition1:11:40 REHIT: Reduced Exertion, High-Intensity Training1:21:59 Does HIIT Prevent Sarcopenia?1:27:27 VO2 Max: Factoring Age and Sex1:34:28 Designing the Ideal Workout Week1:39:14 Importance of Rest Intervals1:45:14 Connect with Martin‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.This episode includes paid sponsorships.

The most decorated woman in motorsports history will tell you she feared losing far more than she loved winning, and that fear is exactly what drove her to the top. In this episode, I’m with racing legend Danica Patrick to unpack the psychology of elite performance, from the “blind faith” that carried her through two decades of racing to the nervous system conditioning she built starting at age 10. What would be possible for you if you learned to channel pressure instead of escaping it?Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSReListen to “Pretty Intense Podcast” on all your favorite platforms!YouTube: https://bit.ly/4cyZPrtSpotify: https://bit.ly/4riCb63Apple Podcasts: https://bit.ly/4s4I1cHGet Danica Patrick’s book, “Pretty Intense” here: https://bit.ly/4rXdH3r📱Connect with Danica PatrickWebsite: https://bit.ly/4lfA9SQYouTube: https://bit.ly/3OVYeCkInstagram: https://bit.ly/4bht0NiTikTok: https://bit.ly/4sCyDNfFacebook: https://bit.ly/3NuajhwX.com: https://bit.ly/3Pdog3XLinkedIn: https://bit.ly/4cWK6mn🙌Thank you to our sponsors:😁Bon Charge - Save 15% at https://bit.ly/4cDyV1G with code DRLYON💪Bodyhealth - Use the code “LYON20” to get 20% off your first order! https://bit.ly/4r2ImeF❤️Timeline - Get 35% off a Mitopure subscription at https://bit.ly/4b2QpmQ📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:YouTube: https://bit.ly/4boCFC3Spotify: https://bit.ly/4cWTbLG📱Connect with Dr. Gabrielle Lyon:Instagram: https://bit.ly/4uk9adcTikTok: https://bit.ly/3OFK3kJX.com: https://bit.ly/4l3YlaXFacebook: https://bit.ly/3MBrJsoLinkedIn: https://bit.ly/3N1nrdLWebsite: https://bit.ly/3NdV2kTBooks: https://bit.ly/4r6ugZKNewsletter: https://bit.ly/402QCAj⏰Timestamps:00:00 Intro of Show02:05 Understanding the Idea of Pressure and Challenge as a Kid05:00 Managing Wins and Losses09:45 Automaticity to Fear11:44 Managing Nervous System under High Pressure17:34 Danica's Pre-Performance Rituals20:21 Performance Becoming One's Identity21:23 Danica Working with Dr. Lyon26:24 Discipline for Proper Recovery28:47 Tips for Someone Going through the Same Issues31:01 Working with Different Doctors34:01 Women's Intuition in Hiring37:14 Women in Male-Dominated Industries41:42 There Are No Shortcuts to Success43:01 Performing in High-Pressure Situations45:51 Importance of Having Alone Time48:34 What is Home Energy?51:20 Flow of State: Passion and Creativity55:51 Medicine in the AI Era59:32 Rapid Fire Q&A‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.This episode includes paid sponsorships.

I’m joined by Dr. Heather Hirsch to debunk the persistent myths surrounding hormone replacement therapy and explain why the 2002 Women’s Health Initiative data was so widely misinterpreted. We discuss how optimized estrogen, progesterone, and testosterone levels can protect your heart, bones, and brain health, helping you move past "normalized suffering" and into a proactive state of longevity. Whether you are in perimenopause or well past the ten-year window, you'll learn how to navigate personalized dosing and clinical data to reclaim your vitality and extend your health span.Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSReListen to “Women’s Health by Heather Hirsch, MD” on all your favorite platforms!Apple Podcasts: https://bit.ly/4l86MlwSpotify: https://bit.ly/4cpmiHuGet Dr. Heather Hirsch’s book, “The Perimenopause Survival Guide” here:https://bit.ly/4r2yXUd📱Connect with Dr. Heather Hirsch:Website: https://bit.ly/4smy4qJYouTube: https://bit.ly/3NdevSHInstagram: https://bit.ly/4sfj11PTikTok: https://bit.ly/46v6Y8sFacebook: https://bit.ly/3OLI4LAX.com: https://bit.ly/3MY4CbmLinkedIn: https://bit.ly/4u6rjeb🙌Thank you to our sponsors:💪Bodyhealth - Use the code “LYON20” to get 20% off your first order! https://bit.ly/4r2ImeF🍳Our Place - Use code “DRLYON” for 10% of sitewide. https://bit.ly/4r77SiU😁Manukora - save 31% plus $25 worth of free gifts. https://bit.ly/4sglER1📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:YouTube: https://bit.ly/4boCFC3Spotify: https://bit.ly/4cWTbLG📱Connect with Dr. Gabrielle Lyon:Instagram: https://bit.ly/4uk9adcTikTok: https://bit.ly/3OFK3kJX.com: https://bit.ly/4l3YlaXFacebook: https://bit.ly/3MBrJsoLinkedIn: https://bit.ly/3N1nrdLWebsite: https://bit.ly/3NdV2kTBooks: https://bit.ly/4r6ugZKNewsletter: https://bit.ly/402QCAj⏰Timestamps:0:00 Intro of Show6:00 Hormone Replacement Therapy: Where Are We Now?11:25 What is Menopausal Hormone Therapy?13:39 How Safe is Hormone Replacement Therapy?18:39 Access on the Studies on HRT23:10 Risks of Hormone Replacement Therapy27:24 Estrogen Does Not Cause Breast Cancer31:19 Estrogen and Accelerated Bone Loss34:51 Preventative Benefits of Estrogen38:47 Lifespan vs. Health Span39:22 When to Start Hormone Replacement Therapy?45:15 Blood Markers47:26 Progesterone: Effects, Timing, Dosage52:38 Testosterone: Effects, FDA Approval, Benefits, Risks1:00:44 Analysing the Numbers1:04:13 Link of HRT and Cognitive Function1:09:28 What Are Women Doing Wrong?‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.This episode includes paid sponsorships.

Male fertility is declining, and most men have no idea why.In this episode of The Dr. Gabrielle Lyon Show, Dr. Gabrielle Lyon sits down with Dr. Michael Eisenberg, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, to break down what truly determines sperm health and reproductive success.They discuss:How metformin, GLP-1 medications, testosterone therapy, and anabolic steroids affect male fertilityWhy sperm count is a powerful biomarker for long-term health and longevityThe role of sleep, muscle mass, exercise, diet, marijuana, and environmental toxins like microplasticsWhether platelet-rich plasma, or PRP, can help severe male infertilityDaily habits that quietly reduce a couple’s chances of conceivingIf you care about fertility, hormones, metabolic health, or the future of men’s health, this conversation is essential.Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comThank you to our sponsors: BodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Carol Bike - Visit https://carolbike.com/ and use code LYON for $100 off your CAROL BikeOneSkin - Get 15% off at https://www.oneskin.co/ with code DRLYONFind Dr. Michael Eisenberg at: Eisenberg Lab: https://med.stanford.edu/eisenberglab.htmlLinkedIn: https://www.linkedin.com/in/michael-eisenberg-9230a429X: https://x.com/DrMEisenbergFind Dr. Gabrielle Lyon at: Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageOrder my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Chapters: 00:00 Sex habits, libido, GLP-1s, and what counts as male infertility01:46 Metformin and male fertility, what the Denmark study found07:27 How long sperm take to regenerate after meds, illness, or chemo09:24 GLP-1 medications, weight loss, and semen quality in men10:52 Testosterone therapy, anabolic steroids, and why sperm shuts down16:41 Sperm as a vital sign, fertility as a window into long term health19:14 Microplastics and environmental toxins found in semen22:21 Paternal age and sperm quality, DNA fragmentation and pregnancy risk26:03 Supplements and nutrients for sperm quality, what matters and why30:00 Sex frequency, masturbation, libido, and fertility myths35:38 Male infertility guidelines and medications that quietly lower fertility48:41 Semen quality and future disease risk, diabetes, cancer, mortality54:45 Anabolic agents, sperm banking, and how long frozen sperm lasts1:04:14 PRP for severe male infertility, azospermia and real outcomes1:16:41 New frontiers in male fertility, immune profiles, genomics, omicsDisclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comSelf-doubt holds more people back than lack of skill or intelligence.In this episode, Dr. Gabrielle Lyon sits down with Dr. Shadé Zahrai to explore the science of confidence, self-trust, and peak performance. They break down why confidence comes after action, how self-image shapes success, and the four psychological drivers that determine whether you thrive or stay stuck.You will learn how body language influences perception, why high performers plan for failure, how perfectionism leads to burnout, and the subtle communication habits that undermine credibility. Most importantly, you will discover how to build what Dr. Zahrai calls Big Trust so you can back yourself before you feel ready.If you struggle with overthinking, imposter thoughts, or feeling capable but not fully confident, this conversation will give you practical tools to change how you show up.CHAPTERS00:00 Confidence science: feeling vs appearing00:51 The opposite of self-doubt and why confidence comes after action01:53 Self-trust before confidence03:03 Nonverbal confidence cues: posture, eye contact, smile, pace07:30 Body language feedback loop: posture and recall09:26 Shadé’s PhD on self-doubt under pressure12:22 What makes people successful: self-image12:30 Self-image blueprint and why change does not stick14:29 The Four A’s: Acceptance, Agency, Autonomy, Adaptability20:26 The self-awareness gap and changing personality traits22:30 Expectation bias and the scar experiment25:54 Self-doubt types: signal vs verdict28:30 Visibility, influence, and the people around you31:16 Which traits are easiest to change35:56 Why capable people still stay stuck40:25 Michael Phelps and visualizing failure recovery42:30 Stop rumination: stimulus control for worry47:45 Self-improvement vs perfectionism vs burnout56:53 The 4 inner deceivers: Judge, Protector, Neglecter, Ringmaster1:11:22 Peak performance and Big Trust1:19:19 Communication habits that kill credibility1:24:18 Stop over-apologizing and reframe emotion1:29:47 Daily habits to build Big Trust and audit your circleThank you to our sponsors: Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyonBodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee with a subscription (just pay for shipping & handling).Find Dr. Dr. Shadé Zahrai at: IG: https://www.instagram.com/shadezahrai/YouTube: https://www.youtube.com/shadezahraiBig Trust by Dr. Shadé Zahrai gives you the tools to quiet self-doubt and step forward with clarity, agency, and confidence. Get your copy here: https://www.amazon.ca/Big-Trust-Self-Doubt-Confidence-Success/dp/0063378159Find Dr. Gabrielle Lyon at: Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.