The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show

The Dr. Gabrielle Lyon Show

Dr. Gabrielle Lyon

Overview
Episodes

Details

The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.

Recent Episodes

STOP Inflaming Your Body: The #1 Enemy to Egg Quality and Conception
DEC 9, 2025
STOP Inflaming Your Body: The #1 Enemy to Egg Quality and Conception

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Dr. Gabrielle Lyon sits down with fertility specialist Dr. Natalie Crawford to tackle the urgent rise in infertility across both men and women. Dr. Crawford, an advocate for proactive reproductive health, reveals why inflammation is hijacking your fertility and why the old dogma that "age is the only factor" for egg quality is dangerously incomplete.

They cover critical, actionable steps—from the most important lifestyle changes you can make before IVF, to the toxic habits that are directly lowering sperm counts and causing miscarriages. Learn the three essential fertility awareness methods (FAMs) and what your doctor is missing when they check your thyroid.


Who is Natalie Crawford:

Natalie Crawford is a double board-certified fertility doctor with a nutrition background, here to help you understand your body and hormones, optimize your lifestyle, and take control of your reproductive future with confidence.


Thank you to our sponsors: 

  • Timeline - Get 20% off your order at https://timeline.com/LYON    
  • BON CHARGE Holiday Sale https://boncharge.com for 25% off 
  • Don’t miss NOBL’s biggest Sale of the Year! Head to NOBLTravel.com for up to 58% off your entire order! 



Find Natalie Crawford at: 



Find Dr. Gabrielle Lyon at: 



Disclaimers: This episode includes paid sponsorships. 


The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.


Timestamps: 

0:00 - Inflammation is Hijacking Your Fertility 

2:00 - The Infertility Crisis: 1 in 5 Couples Struggle 

3:41 - Male vs. Female: Who is Becoming More Infertile? 

4:03 - Sperm Counts Down 50% & The Rise of Premature Menopause 

4:57 - The #1 Cause of Infertility: Chronic Inflammation 

6:08 - Egg Quality: You CAN Influence Your Mitochondrial Health 

8:18 - The 5 Pillars of Fertility: Sleep, Stress, Muscle, Diet, Toxins 

8:53 - The Foundation: Why Sleep is Non-Negotiable for Hormones 

11:13 - Fertility is a Team Sport: Why Sleep Impacts Men More Quickly 

12:55 - How Much Sleep Do You Need? (Circadian Rhythm is Crucial) 

15:19 - Supplements and Herbs: The Danger of Chaste Tree Berry (Vitex) 

18:38 - The Problem with Glandular & Adrenal Support Supplements 

22:31 - Alcohol and Cannabis: Why They are Profoundly Inflammatory 

24:49 - Miscarriage Risk: Male Cannabis Use & Uterine Septum 

25:57 - Autoimmune Disease: Celiac, Thyroid, and Miscarriage 

28:03 - Celiac Disease: Treating the Root Cause of Inflammation 

29:32 - The Fellow's Journey: Why Dr. Crawford Studied Natural Fertility 

33:24 - The 12-Month Prep Plan: Screening for Autoimmunity (Thyroid/Celiac) 

34:07 - Hashimoto's & Thyroid: Why Your TSH Range is Misleading 

37:34 - Period Problems: When a "Regular" Cycle Isn't Ovulating Optimally 

40:27 - Thyroid Treatment: Synthetic vs. Animal-Derived Hormones 

44:09 - Environmental Toxins: Their Huge Role in Fertility & Ovarian Reserve 

46:09 - Where to Start: Water, Air Filters, and Non-Teflon Cookware 

48:54 - Toxins: Stainless Steel, Glass, and Avoiding Hot Plastic 

50:45 - Processed Foods and Takeout: The Danger of Packaging 

54:24 - Sex for Conception: How Much is Enough? (No Need to Abstain) 

56:41 - Use It or Lose It: Why the Vagina Can Atrophy 

57:56 - The 3 Fertility Awareness Methods (FAMs) to Track Ovulation 

1:00:59 - Basil Body Temperature & Wearable Tech for Ovulation

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62 MIN
Carbs vs. Protein: Which Macronutrient Is Actually More Dangerous to Overconsume?
DEC 2, 2025
Carbs vs. Protein: Which Macronutrient Is Actually More Dangerous to Overconsume?

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Dr. Gabrielle Lyon reveals the biggest mistakes Americans make with their nutrition and body composition, especially after age 40. With 75% of Americans overweight or obese, the problem is clear: excess calories from cheap, processed carbohydrates.

Dr. Lyon dissects the metabolic science, explaining why skeletal muscle—the largest organ—is not designed to dispose of the massive carb loads found in the average American diet. Learn the essential strategies, including the 1:1 Protein-to-Carbohydrate Ratio Rule and the importance of Carbohydrate Tolerance, to design a meal plan that maximizes muscle, controls insulin, and guarantees success.


Nick Barringer is an expert on nutrition and performance for the tactical athlete. Nick Barringer currently serves as the Program Director for the Army-Baylor University Master’s Program in Nutrition. Barringer has a Doctorate degree in Kinesiology from Texas A&M University and received his undergraduate degree in dietetics from the University of Georgia. Barringer previously served as an assistant professor at the United States Military Academy at West Point and as the Regimental Nutritionist and as a member of the Ranger Athlete Warrior (RAW) program at the 75th Ranger Regiment. Nick has gone through physically demanding courses such as Ranger School, Survival Evasion Resistance Escape(SERE), Airborne, Air Assault as well as having deployed to both Iraq and Afghanistan.


Thank you to our sponsors: 

BodyHealth - Use the code LYON 20 to get 20% off your first order bodyhealth.com

PIQUE - Get 20% off for life + a complimentary gift Piquelife.com/DRLYON

Timeline - Get 20% off your order at https://timeline.com/LYON   

OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co

Find Nick at: 


Find Dr. Gabrielle Lyon at: 



Disclaimers: This episode includes paid sponsorships. 


The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

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54 MIN
Over 70 and Shredded: The Guide to Building Muscle at Any Age | Michelle & Joan MacDonald
NOV 25, 2025
Over 70 and Shredded: The Guide to Building Muscle at Any Age | Michelle & Joan MacDonald

Want ad-free episodes and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Become a patient: https://strongmedical.com/apply-now/?utm_source=youtube&utm_medium=video&utm_campaign=strongmedical&utm_content=description


In this empowering episode, Dr. Gabrielle Lyon sits down with the incredible mother-daughter duo, Michelle and Joan MacDonald, to share the blueprint for radical physical transformation at any age. Joan, who began her journey nearing 71 years old, proves it's never too late, while coach Michelle, a Certified Strength and Conditioning Specialist (CSCS), cuts through the noise on training, nutrition, and mindset.


They tackle deeply personal topics, including Michelle's 15-year struggle with a severe eating disorder and the shame that surrounds women's health. This is a must-watch to learn the non-negotiable pillars for building a strong, resilient, and healthy body, no matter your starting point.


Michelle MacDonald is a trailblazer in the global movement to redefine aging and female

empowerment through strength. As the founder of The Wonderwomen, a world-class coaching

brand built on her signature methodology, The Fitness Model Blueprint™, Michelle has

transformed thousands of women—inside and out—with evidence-based strategies that merge

mindset, muscle, and metabolic mastery.


Joan MacDonald (Fitness Icon and Mother)

At 70, Joan MacDonald was getting winded walking up a flight of stairs and now, at 74, she is doing weighted pull-ups and 200 lb hip thrusts.


This episode is sponsored by:

- Branch Basics - 15% off and free shipping on the Starter Kit when you use code DRLYON at BranchBasics.com/DRLYON

- BON CHARGE Holiday Sale https://boncharge.com for 25% off

- Manukora - BLACK FRIDAY SALE: Save $151 on Manukora Starter Kit MANUKORA.com/DRLYON


Chapters:

0:00 - The ED Crisis: Michelle’s 15-Year Battle & Recovery

2:04 - Joan Started Lifting at 71: Debunking the Age Myth

6:16 - Pillars of Transformation: Mindset, Sleep, Food

8:52 - Finding Your "Why": Aesthetics vs. Longevity

12:01 - Why Strength Training Must Come First

14:28 - Grittiness: The Secret to Joan's Radical Success

24:54 - Hard Truths: The "Nursing Home" Speech That Changed Joan's Life

26:47 - The Transformation Container: Non-Negotiables for Success

47:03 - Disordered Eating: When to Get Expert Therapy vs. Coaching

50:11 - GLP-1s and the "Food Noise" Solution

58:12 - 3 Essential Beginner Exercises (Joan's Choices)

1:04:22 - Strength Goals: The 3 Exercises a Strong 40-Year-Old Must Master

1:10:29 - The Hip Thrust: #1 Glute Builder and Muscle Mandate

1:14:09 - Training is a Skill: How to Prevent Injury

1:19:11 - Core Strength: Why Glutes and Abs Prevent Falls

1:33:37 - Training the Individual: Why Age Doesn't Matter

1:37:29 - Nutrition Blueprint: Protein First for Satiety and Adherence


Find Michelle at:

https://www.instagram.com/yourhealthyhedonista/

http://MichelleMacdonaldOfficial.com

Podcast: https://podcasts.apple.com/us/podcast/the-wonder-women-official/id1677831398


Find Joan at:

https://www.instagram.com/trainwithjoan

https://www.trainwithjoanofficial.com


Find Dr. Gabrielle Lyon at:

- Instagram:@drgabriellelyon

- TikTok: @drgabriellelyon

- Facebook: facebook.com/doctorgabriellelyon

- YouTube: youtube.com/@DrGabrielleLyon

- X (Twitter): x.com/drgabriellelyon

- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623


Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

This episode includes paid sponsorships.

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103 MIN
TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity
NOV 18, 2025
TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

In this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments.

You'll learn:

  • Why aging alone doesn't drop T levels and why acquisition of conditions like obesity is the real culprit.
  • Why the standard "low T" cutoff is misleading and why you must check your Free Testosterone.
  • How erectile dysfunction is a sensitive marker of overall health and heart risk.
  • The efficacy of Cialis/Viagra for both erections and cardiac protection, and the risks of unchecked influencer advice on steroids.
  • The direct link between muscle mass, exercise, and sexual function—and why the penis is the "first to go" when overall health declines.

Chapter Markers:

0:00 - Testosterone is a Brain Hormone

0:40 - Debunking the Myth: Male Menopause (Andropause) Doesn't Exist

1:33 - The Dangers of Unchecked Influencer Advice on Testosterone

3:07 - Defining Testosterone Deficiency: Symptoms vs. Signs

5:10 - The Arbitrary Number: Why Guidelines Disagree on Low T

8:29 - Free Testosterone: The Most Reliable Indicator of Male Health

15:28 - TRT vs. Steroids: Defining the Line and Risks

18:59 - The Real Risks of TRT: Infertility and Hematocrit

22:36 - The Shocking Backstory: Challenging the Prostate Cancer Myth

26:40 - Erectile Dysfunction (ED) and Lifestyle Modification

29:21 - Shockwave Therapy for ED: The Science and the Cash Business

33:53 - Penile Tissue Atrophy and Venous Leak

37:25 - The Role of Muscle Mass, Sarcopenia, and Sexual Function

39:41 - The Single Best Marker for Male Health: Erectile Function

42:02 - The Science of Cialis and Viagra (PDE5 Inhibitors)

45:49 - The Viagra Story: From Heart Drug to ED Cure

50:50 - Tadalafil (Cialis) as a Triple-Threat Drug (Cardiac, Urinary, Sexual)

53:57 - The Role of Testosterone in Female Sexual Function

55:20 - Hypogonadism: Diagnosis, Treatment, and Fertility Risk

About the guests:

Dr. Abraham Morgentaler is an Associate Clinical Professor of Urology at Harvard Medical School and founder of Men's Health Boston. He is an internationally recognized expert in men's health, particularly known for his pioneering work in testosterone therapy. Dr. Morgentaler is credited with reversing the long-held belief that testosterone therapy causes prostate cancer and is the author of several books on men's health.


Dr. Tobias Kohler is the co-founder of the Erectile Restoration Outcomes Study (EROS) penile implant registry. In addition to his clinical and research activities, Dr. Kohler is active in education, providing mentorship to residents and fellows.


Dr. Mohit Khera, M.D., M.B.A., M.P.H., is a urologist and professor at Baylor College of Medicine. He is an expert in male and female sexual dysfunction and testosterone replacement therapy, and his work focuses on male infertility, sexual dysfunction, and declining testosterone levels. He is also the President of the Sexual Medicine Society of North America.


Thank you to our sponsors:

  • Hollow Socks - Buy 3, Get 3 Free at https://hollowsocks.com
  • Cozy Earth - https://cozyearth.com/DRLYON for up to 40% off
  • Timeline - Get 20% off your order at https://timeline.com/LYON
  • Our Place - Save up to 35% sitewide through December 2nd at https://fromourplace.com

Disclaimers:

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

This episode includes paid sponsorships.

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99 MIN
Neuroscientist Explains MDMA and The Science of Social Connection |  Dr. Ben Rein Ph.D.
NOV 11, 2025
Neuroscientist Explains MDMA and The Science of Social Connection | Dr. Ben Rein Ph.D.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

In this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.

They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.

Chapter Markers:

0:00 - MDMA (Molly): The History & Therapeutic Benefits

5:59 - The Legal Status of MDMA for PTSD

6:44 - The Safety and Effectiveness of MDMA in Clinical Trials

8:29 - PTSD (The Amygdala Alarm)

9:41 - How MDMA Soothes the Amygdala to Access Memory

11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism)

13:16 - Ketamine and Neuroplasticity for Depression

15:48 - Botox and Empathy:

18:12 - The Problem of Volume: How Screens Depersonalize Interaction

19:48 - The Virtual Disengagement Hypothesis Explained

25:00 - Defining Cognitive and Emotional Empathy

29:43 - MDMA's Link to Serotonin & Social Reward

31:04 - Do SSRIs Have Pro-Social Effects?

36:10 - The Science of Likability and "Easy to Read" Faces

40:10 - Top 3 Ways to Be More Likable

49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are

56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin

1:09:23 - The Goldilocks Zone of Empathy

1:15:58 - Narcolepsy

1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health

1:21:47 - Exercise and Neurogenesis

1:22:27 - Sex, Orgasm, and Oxytocin Release

1:25:06 - Oxytocin During Childbirth

Who is Ben Rein:

Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.

Thank you to our sponsors:

BodyHealth: Use code LYON20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/

BON CHARGE Holiday Sale https://boncharge.com for 25% off

Pique 20% off for life: https://Piquelife.com/DRLYON

Find Ben Rein at:


Find Dr. Gabrielle Lyon at:

  • Instagram:@drgabriellelyon
  • TikTok: @drgabriellelyon
  • Facebook: facebook.com/doctorgabriellelyon
  • YouTube: youtube.com/@DrGabrielleLyon
  • X (Twitter): x.com/drgabriellelyon
  • Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
  • Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
  • Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimers:

This episode includes paid sponsorships.

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

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87 MIN