The Dr. Gabrielle Lyon Show

Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-chief of the Journal of Clinical Lipidology, to discuss:Why ApoB and Lp(a) are better predictors of heart risk than LDL and why only about 2% of people ever get Lp(a) testedWhat a beef-vs-chicken feeding study revealed about red meat and cholesterol (the LDL results came back identical at 112 mg/dL)The evidence behind the seed oil debate, including why higher linoleic acid levels tracked with lower inflammation markers across a 2,000-person datasetWhy the balance of cholesterol-raising and cholesterol-lowering foods matters more than saturated fat aloneThe simple "ABCs" framework: A1c, blood pressure, cholesterol - for actually lowering long-term cardiovascular riskBy the end, you'll know which numbers actually predict heart risk, which tests to ask your doctor for, and how to cut through the conflicting noise around fat so you can make evidence-based decisions for the long haul.Thank you to our sponsors:OneSkin - Get 15% off at https://bit.ly/4tZnOpk with code DRLYONBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7AC Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Kevin Maki at:Midwest Biomedical Research: https://www.mbclinicalresearch.com/ LinkedIn: / kevin-c-maki-phd-497ba34 Connect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon Chapters00:00 - Introduction00:31 - Dr. Kevin Maki and the National Lipid Association01:04 - New dietary guidelines and the LDL confusion02:04 - What raises and lowers LDL cholesterol03:51 - Cholesterol levels from birth through puberty05:11 - The lipid panel kids should get before age 1106:42 - Lp(a): the test only 2% of people get08:18 - ApoB and the three risky particle types11:35 - Do we have evidence for "lower is better"?14:09 - The FLASH-GLICK risk factor framework17:10 - The 10% saturated fat guideline explained19:36 - Many dietary patterns can be healthy24:50 - Beef vs. chicken: identical LDL results27:10 - The balance of fatty acids that matters29:24 - Olive oil vs. corn oil feeding study31:00 - Lower for longer: 40-year risk reduction34:15 - Genetic cholesterol disorders and risk40:33 - The omega-3 index and why it matters49:10 - Are seed oils really driving inflammation?53:11 - How seed oils are processed and refined1:07:48 - Inherited beliefs and outdated nutrition science1:08:54 - Butter vs. cheese and high-fat dairy surprises1:14:48 - Exercise effects on HDL and triglycerides1:21:20 - The ABCs of reducing cardiovascular riskIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder of a Miami-based gastro-metabolic clinic, to discuss:The specific warning signs every adult under 50 should never ignore, regardless of age including rectal bleeding, unintentional weight loss, and persistent abdominal painWhy GLP-1 medications like Ozempic and Zepbound are being miscategorized as weight loss drugs when they're actually metabolic reprogrammers with applications in fatty liver, sleep apnea, and inflammationThe protein, fiber, and resistance training protocol Dr. Pearlman uses to protect muscle mass in patients on GLP-1 therapyHow hormone replacement therapy combined with GLP-1s is changing body composition outcomes for perimenopausal women and why current guidelines are still 20 years behind the dataDr. Pearlman's personal osteoporosis diagnosis at 39, despite being a lifelong bodybuilder, and what it revealed about the diagnostic gaps in standard medicineThis conversation gives you the framework to recognize the warning signs most physicians are still missing, and the foundational habits; nutrition, resistance training, and hormone optimization that protect your gut, bones, and muscle through midlife and beyond.Thank you to our sponsors: Cozy Earth - Go to https://bit.ly/4teXQhz for up to 20% off!Timeline - Get 20% off your Mitopure order at https://bit.ly/4eLBWhBLucy - Get 20% off your next order with code DRLYON at https://bit.ly/42HiUlc, or find yours in store at https://bit.ly/3RfGnYaAmp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Michelle Pearlman at:Instagram: https://www.instagram.com/michellepearlmanmd/Website: https://www.primeinstitute.us/Connect with Dr. Gabrielle LyonInstagram: https://www.instagram.com/drgabriellelyon/TikTok: https://www.tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction: Colorectal cancer under 5001:15 - The gastro-metabolic approach explained03:30 - Why nutrition isn't taught in GI fellowship05:45 - When the colonoscopy is normal but patients suffer07:00 - Weight, reflux, and visceral fat09:15 - PPIs, bone density, and long-term risk11:30 - Three things to never do for gut health14:00 - Ultra-processed food and early-onset cancer16:45 - Rectal bleeding, warning signs, and age19:00 - Screening guidelines and the obesity gap22:30 - GLP-1 medications: history and mechanism27:15 - Hunger, cravings, and food noise30:00 - The stigma around metabolic medications33:45 - Side effects: nausea, reflux, constipation38:30 - Compounded formulations and pharmacy safety42:00 - Hair loss, protein, and supplementation45:15 - Pill versus injection delivery systems49:30 - Fiber, the microbiome, and short-chain fatty acids54:00 - GLP-1s plus hormone replacement therapy58:45 - Testosterone, Kyzatrex, and women's bone health1:03:00 - Pearlman's osteoporosis diagnosis at 391:09:30 - The diagnostic gap in standard medicine1:14:00 - Building Bite MD and the future of nutrition techDisclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:Why the "apex parent / apex kid" mindset is a quiet trap, and what to do instead of paving the roadHow nature vs nurture actually plays out and what you can and cannot shape in your childThe one trait Jocko wants his kids to inherit (and why every virtue becomes a vice when pushed to the extreme)The lie that successful, high-functioning people tell themselves about wanting moreThe single most important trait of a great leader and the one habit Jocko says will make every other part of your life better starting tomorrowYou'll walk away with a clearer operating system for the kind of parent, leader, and person you actually want to be and the one habit Jocko swears is the highest-ROI move any human can make.Thank you to our sponsors: BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7ACOur Place - Visit https://bit.ly/4c8OrAB and use code DRLYON for 10% off sitewide.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4eu4Mm8 with the code DRLYON.Amp - Visit https://bit.ly/41BvjXj to get your AI-powered at-home gym for smarter, personalized training.Watch on Spotify. If you’re subscribed to Spotify Premium, you don’t get any Spotify ads on my video.Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find JOCKO WILLINK at:Instagram: https://www.instagram.com/jockowillink/?hl=enFacebook: https://www.facebook.com/jkowillink/Tiktok: https://www.tiktok.com/@jocko_willinkX: https://x.com/jockowillinkYouTube: https://www.youtube.com/@JockoPodcastOfficialLinkedin: https://www.linkedin.com/in/jocko-willink-260b289/Get Jocko Willink’s books: https://jocko.com/books/Connect with Dr. Gabrielle LyonInstagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction: Leadership and parenting are the same skill03:24 - Nature vs nurture and the kids who won't compete06:56 - The guardrails of failure07:48 - Dharma and the path kids are meant to walk09:17 - The one trait Jocko wants his kids to inherit11:33 - What daughters should learn about men from their fathers13:32 - How men and women experience fear differently14:24 - Rebuilding trust after good people do bad things18:34 - Letting your daughter do cheerleading21:22 - Hiring people by putting them in the real environment24:22 - The lie successful people tell themselves29:16 - Strategic thinking vs the donut decision35:18 - What failure teaches that success cannot38:25 - Why Jocko stopped being about himself44:09 - Aging, losing movements, and rage against the dying of the light46:49 - Why a leader has to be in physical shape50:41 - The single most important trait of a leader54:09 - The one habit that changes everythingIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. specialists treating chronic pelvic pain in men, to discuss:Why "prostatitis" is often the wrong diagnosis, and how rounds of antibiotics mask the real problemThe male pelvic floor anatomy almost no medical school teaches, and how to recognize dysfunction in yourself or a patientOff-label medications (Cymbalta, gabapentin, amitriptyline) that are quietly transforming chronic pelvic pain treatmentWhy erectile dysfunction is rising sharply in teenagers, and the role pornography plays in rewiring young brainsWho actually qualifies for a penile implant, and what the surgery really involvesIf you've been told your pain is "all in your head," or you're a clinician seeing patients fall through the cracks, this conversation gives you the framework, the language, and the next steps to find real answers.Thank you to our sponsors: Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://www.timeline.com/lyonBONCHARGE - Save 15% at https://boncharge.com/ with code DRLYONExplore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/Find Dr. Susan Macdonald at:Instagram: https://www.instagram.com/drsusanmacdonald/X (Twitter): https://x.com/smacdonald_mdLinkedIn: https://www.linkedin.com/in/susan-macdonald-506324191/Connect with Dr. Gabrielle LyonInstagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 - Introduction01:42 - Meet Dr. Susan Macdonald03:00 - The high-powered lawyer nobody could help05:01 - Why testicle pain is 5% of urology visits07:49 - Men have a pelvic floor (and what it does)12:46 - How a man knows he has pelvic floor dysfunction21:30 - Why these muscles are "too tight" in men26:33 - Chronic pain rewires the brain29:21 - Stress, trauma, and the mind-body connection33:29 - Stretching, breathing, and self-treatment at home36:21 - The medications that actually work (Cymbalta, gabapentin)44:34 - Muscle relaxers, acupuncture, and the guidelines panel55:09 - Sexual trauma and chronic pelvic pain01:00:08 - The "pain plus" diagnostic framework01:05:23 - The micro-surgical denervation surgery01:08:36 - Erectile dysfunction in 17-year-olds01:11:00 - How porn rewires young men's brains01:18:27 - 40% of men by 40, 50% by 5001:23:39 - Penile implants: who qualifies, how they work01:28:10 - Stage 4 cancer at 42 and the pivot to teaching01:34:17 - Living big with finite time01:39:00 - Closing message to chronic pain patientsIf you found this episode valuable, share it with someone who would benefit from it.This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:Why strength training is essential at every age but most people are defining "strength" too narrowlyHow modern life has created an "exercise deficiency," and why artificial exercise is the only fixThe truth about fat, protein, and the biggest nutrition mistakes holding people back from lasting weight lossThe emerging peptide and drug landscape, and what it means for the future of health optimizationWhy forcing your kids to move isn't cruelty, it's one of the most protective things you can do as a parentWhether you're 25 or 75, this episode will challenge how you think about movement, muscle, and what it actually means to be strong physically and mentally.Thank you to our sponsors:OneSkin - Get 15% off with code DRLYON — https://bit.ly/4tZnOpkAmp - Get your AI-powered at-home gym for smarter personalized training — https://bit.ly/41BvjXjBranch Basics - Get 15% off the Premium Starter Kit with the code DRLYON — https://bit.ly/4eu4Mm8BodyHealth - Get 20% off your first order with the code LYON 20 — https://bit.ly/4etWlr5Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content — https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights — https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team — https://drgabriellelyon.com/new-patient-inquiry/Find Mark Bell at:https://www.instagram.com/marksmellybell/https://www.youtube.com/@MarkBellSuperTrainingSlingshot: https://originmaine.com/Connect with Dr. Gabrielle LyonInstagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyonChapters00:00 – Introduction02:48 – Mark Bell's Motto07:00 – Mind-Body Strength Connection10:45 – Wrestling > Powerlifting > Entrepreneurship Journey17:37 – Rationale of Goals22:04 – Effects of Consistency and Efficiency in Training32:55 – Recommended Training and Lifestyle Modalities37:32 – Artificial Exercise vs. Exercise Deficiency37:47 – "Artificial Exercise" and "Exercise Deficiency"39:36 – Impact of Physical Activity in Children44:57 – Biggest Mistake in Weight Loss50:46 – Overconsumption is a Problem53:17 – Era of GLP-1, Peptides, and Steroids1:02:28 – Training to Decrease Mortality1:03:33 – Cancer Research Updates1:04:36 – Collective Research on Supplementation1:16:50 – Influencing Children to Engage in Physical ActivitiesShare This Episode If you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.