Infectious Disease Puscast

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• Viral
• Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine)
• Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID)
• Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID)
• HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID)
• Bacterial
• Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection)
• Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism)
• Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA)
• Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID)
• Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases)
• A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM)
• Fungal
• The Last of US Season 2 (YouTube)
• Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID)
• British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases)
• In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID)
• Parasitic
• Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice)
• WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO)
• Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health)
• A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases)
• Miscellaneous
• IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

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• Viral
• High Prevalence of Varicella Zoster Virus Infection among Persons with Suspect Mpox Cases during an Mpox Outbreak in Kenya, 2024 (ASTMH: AJTMH)
• Earlier initiation of treatment following HIV acquisition reduces non-AIDS-defining malignancy risk (CID)
• TWiV 1267: A cancer vaccine and an mpox treatment (MicrobeTV)
• Cancers Caused by HPV (CDC: Human Papillomavirus (HPV))
• Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of the National Cancer Institute)
• Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine—A Systematic Review (Viruses)
• ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP))
• HPV Vaccination Recommendations (CDC: Vaccines & Immunizations)
• Bacterial
• Consequences of Delaying Surgical Intervention in Patients with Native Joint Septic Arthritis (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial (LANCET: Respiratory Medicine)
• Nasal Iodophor to Reduce Candidozyma auris Nasal Carriage in Nursing Home Residents (OFID)
• Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients (Journal of Pediatric Infectious Diseases Society)
• Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database (OFID)
• Genomic Dynamics of the Emergent Candida auris: Exploring Climate-dependentTrends (OFID)
• Parasitic
• Evaluation of a One Health public health program based on minimum inputs to control Taenia solium in Madagascar (PLoS Neglected Tropical Diseases)
• Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood (CID)
• Miscellaneous
• Amplifying Our Voices: Fostering Advocacy in Infectious Diseases Fellowship(OFID)
• Plant-Based Diets and Climate Change, A Perspective for Infectious Disease Provider (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

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• Viral
• Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID)
• Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID)
• Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID)
• Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID)
• The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID)
• Bacterial
• Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology)
• Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM)
• Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection)
• Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio)
• Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy)
• Parasitic
• Miscellaneous
• CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID)
• Infection Control in Carceral Facilities (CID)
• Infection Prevention and Control in Carceral Settings (CID)
• The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research)
• SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature)
• TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV)
• Infected With the Academic Bug (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

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Become a patron of Puscast!

• Viral
• American Academy of Pediatrics
• Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza(JAMA: Open Network)
• Flu and Children (CDC: Influenza (flu))
• Bacterial
• Performance of Different Versions of Duke Criteria in Diagnosing Infective Endocarditis in Patients With Intracardiac Prosthetic (OFID)
• 2023 Duke criteria on Infectious Disease (Puscast 28)
• Infective Endocarditis and Antimicrobial Timing: A Case for Delay? (OFID)
• Tularemia: A Storied History, An Ongoing Threat (CID)
• Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR)
• Fungal
• The Last of US Season 2 (YouTube)
• Risk factors associated with progression to clinical Candida auris infection among adults with previous colonization—Florida, 2019–2023 (CID)
• Parasitic
• Public Health Response to the First Locally Acquired Malaria Outbreaks in the US in 20 Years (JAMA: Open Network)
• Miscellaneous
• Fever in sepsis revisited: Is a little heat what we need? (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of Puscast!

• Viral
• Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide (OFID)
• Tracking County-Level Measles Cases in the US (JAMA Nework)
• Tracking measles in US (Hopkins)
• Pediatric influenza-associated encephalopathy and acute necrotizing encephalopathy (MMWR)
• Clinical recommendations for Lenacapivir (MMWR) Bacterial
• Primary oral vancomycin prophylaxis to stem an outbreak of Clostridioides difficile infection in intensive care patients (Antimicrob Steward Healthc Epidemiol)
• Clinical features and treatment strategies of Q fever spinal infection (OFID) Fungal
• Last of Us Season 2
• The Pain is in the Brain (J Inf Dis) Parasitic
• Chagas Disease, an Endemic Disease in the United States (MMWR)
• Fixed-dose ivermectin for Mass Drug Administration (PLoS NTD)
• Outbreak of eosinophilic meningitis caused by the rat lungworm (Angiostrongylus cantonensis) in South Brazil (Am J Trop Med Hyg)
• Human monoclonal antibody MAM01 for protection against malaria in adults in the USA (Lancet Inf Dis)
• Permethrin-Treated Baby Wraps for the Prevention of Malaria (NEJM) Miscellaneous
• Ambient Documentation Technology in Clinician Experience of Documentation Burden and Burnout (JAMA Network Open)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.