<p>In this episode, we discussed the management of systemic mastocytosis with Dr. Daniel DeAngelo from the Dana Farber Cancer Institute. Here are the key studies we discussed:</p><ul><li>Midostaurin <a href="https://www.nejm.org/doi/10.1056/NEJMoa1513098?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov">https://www.nejm.org/doi/10.1056/NEJMoa1513098?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov</a></li><li>Avapritinib</li><li>EXLPORER study: <a href="https://www.nature.com/articles/s41591-021-01538-9">https://www.nature.com/articles/s41591-021-01538-9</a></li><li>PATHFINDER study: <a href="https://www.nature.com/articles/s41591-021-01539-8">https://www.nature.com/articles/s41591-021-01539-8</a></li><li>Bezuclastinib: APEX trial: <a href="https://ashpublications.org/blood/article/144/Supplement%201/659/530240/Apex-Part-1-Updated-Assessment-of-Bezuclastinib">https://ashpublications.org/blood/article/144/Supplement%201/659/530240/Apex-Part-1-Updated-Assessment-of-Bezuclastinib</a></li><li>HSCT for Advanced SM: <a href="https://ascopubs.org/doi/10.1200/JCO.2014.55.2018">https://ascopubs.org/doi/10.1200/JCO.2014.55.2018</a></li></ul>

Blood Cancer Talks

Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff

Episode 59. Management of Systemic Mastocytosis with Dr. Daniel DeAngelo

MAY 8, 202563 MIN
Blood Cancer Talks

Episode 59. Management of Systemic Mastocytosis with Dr. Daniel DeAngelo

MAY 8, 202563 MIN

Description

In this episode, we discussed the management of systemic mastocytosis with Dr. Daniel DeAngelo from the Dana Farber Cancer Institute. Here are the key studies we discussed:Midostaurin https://www.nejm.org/doi/10.1056/NEJMoa1513098?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.govAvapritinibEXLPORER study: https://www.nature.com/articles/s41591-021-01538-9PATHFINDER study: https://www.nature.com/articles/s41591-021-01539-8Bezuclastinib: APEX trial: https://ashpublications.org/blood/article/144/Supplement%201/659/530240/Apex-Part-1-Updated-Assessment-of-BezuclastinibHSCT for Advanced SM: https://ascopubs.org/doi/10.1200/JCO.2014.55.2018