Give and Toke
Give and Toke

Give and Toke

Paul O'Donoghue

Overview
Episodes

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Give & Toke is a podcast about cannabis, told through the people living and building it. Hosted by Paul O’Donoghue, each episode features conversations with patients, doctors, advocates and operators, exploring access, regulation, culture and the realities of the industry. Grounded, curious and at times uncomfortable, the show aims to move beyond headlines and into what actually matters.

Recent Episodes

Culture Can't Be Mass Produced w/ Remi-Dean Ryan (Sativite)
JUN 28, 2026
Culture Can't Be Mass Produced w/ Remi-Dean Ryan (Sativite)
This podcast is supported by Azure Health. Visit azurehealth.com.au/giveandtoke to learn more.Remi-Dean Ryan is a long-time industry operator who has worked across almost every layer of the Australian cannabis ecosystem. From cultivation and post-harvest through to pharmacy, genetics, packaging and supply chain, he has seen how the system actually functions from the inside out.Now working with Sativite, Remi brings a rare end-to-end perspective on the realities of medical cannabis in Australia, beyond the headlines and hype, grounded in lived experience across the full lifecycle of the plant.What makes Remi’s story compelling is his ability to move between two worlds that do not always align. He is deeply connected to cannabis culture and community, while also operating within a highly regulated medical framework. It is a balance many struggle to hold, and in this conversation he speaks openly about what that looks like in practice.Together, Paul and Remi unpack the current state of the Australian cultivation market, the pressures facing local growers, and whether the system is set up for long-term sustainability.They also explore what it means to stay connected to the roots of the plant and to community in an industry increasingly shaped by regulation, scale and commercial reality.Research Note: This episode also touches on a broader theory popularised by Kevin Jodrey: that the removal of hemp as a common agricultural and dietary input may have contributed to modern endocannabinoid dysregulation. While compelling, this remains largely theoretical. It sits adjacent to the work of Ethan Russo, whose Clinical Endocannabinoid Deficiency hypothesis explores how dysfunction in the endocannabinoid system may contribute to conditions like migraine, fibromyalgia and IBS.Follow @remideanofficial on InstagramFind Remi-Dean Ryan on LinkedinVisit www.giveandtoke.com.auFollow @giveandtoke on InstagramEmail [email protected]
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52 MIN