Breast Cancer Trials

Treatment for triple-negative breast cancer has advanced significantly, but challenges remain when, in some cases, the disease returns after treatment. In this episode, we sit down with Dr Belinda Yeo to explore treatment options for triple-negative breast cancer patientswhose cancer has that has relapsed. Dr Yeo discusses the challenges clinicians face when deciding what treatment to offer next, emerging therapies showingpromise, and the critical role that clinical trials continue to play in improving outcomes for people with triple-negative breast cancer. (3:03) If a patient's cancer does return after these therapies, what are clinicians' biggest challenges in determining what treatment to offer next? (04:21) As a clinician, what treatment approaches or emerging therapies for triple-negative breast cancer are giving you the most optimism? (06:05) How important is participation in clinical trials? (07:21) What is one key message that you'd like patients navigating triple-negative breast cancer to take away from this episode? Tune in for a deep dive into this important research. Like this episode? ⁠⁠ Follow Breast Cancer Trials on Social Media: Instagram:⁠ @breastcancertrials Facebook:⁠ ⁠Breast Cancer Trials LinkedIn: Breast Cancer Trials X: ⁠⁠@BCTrialsANZ Guest: Medical Oncologist, Dr Belinda Yeo. Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of clinical trials research.

Invasive lobular carcinoma is the second most common type of breast cancer, yet there is still much to learn about what makes this disease biologically distinct. In this episode, we sit down with Associate Professor Amy McCart Reed to explore the molecular underpinnings of invasive lobular carcinoma. Associate Professor McCart Reed discusses what researchers are learning about the biology of invasive lobular carcinoma, recent discoveries shaping our understanding of the disease, and how this research could ultimately lead to more personalised treatments and better outcomes for people living with a lobular diagnosis. (2:01) What have been some of the biggest discoveries in recent years that are changing the way researchers think about this subtype of breast cancer? (02:57) Are we aiming to move more towards personalised treatment for breast cancer? (03:27) What research still needs to happen in this space? (05:17) What is the key message that you'd like researchers and clinicians to take away from this episode? Tune in for a deep dive into this important research. Donate to support live-saving research. Like this episode? ⁠⁠ Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠@breastcancertrials Facebook:⁠ ⁠Breast Cancer Trials LinkedIn: ⁠⁠Breast Cancer Trials X: ⁠⁠@BCTrialsANZ Guest: Molecular Biologist, Associate Professor Amy McCart Reed. Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of clinical trials research.

Could Patients with Breast Cancer Safely Skip Radiation & the Potential Side Effects? Inside the ROSALIE Clinical Trial Could skipping radiation after breast-conserving surgery be safe for some patients? The ROSALIE trial is exploring this possibility. In this episode, we sit down with Professor Boon Chua, Radiation Oncologist and Professor of Medicine at the University of New South Wales, who leads the Breast Cancer Trials ROSALIE clinical trial. Professor Chua discusses how the study aims to de-escalate treatment for women with early-stage breast cancer who achieve a complete response to chemotherapy, potentially reducing side effects without compromising outcomes. (2:06) What is the ROSALIE clinical trial hoping to find out? (2:51) How could this research change the way we treat breast cancer in the future, especially for patients with early-stage disease? (3:30) What would you like patients and the public to understand about the importance of participating in trials like this? Tune in for a deep dive into this important research. ⁠⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠⁠ Like this episode? ⁠⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠⁠ Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠⁠@breastcancertrials⁠⁠⁠⁠ Facebook:⁠ ⁠⁠⁠Breast Cancer Trials⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠Breast Cancer Trials⁠⁠⁠⁠ X: ⁠⁠⁠⁠@BCTrialsANZ⁠⁠⁠⁠ Guest: Medical Oncologist, Dr Boon Chua. Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about the importance of clinical trials research.

Neoadjuvant Now: What's Next in Pre-Surgical Breast Cancer Treatment? More and more breast cancer patients are now receiving treatment before surgery - but what’s next for this approach? In this episode, we look at how neoadjuvant therapy is changing, the new treatments being tested, and what it could mean for patients in the future. Hear from the Head of the International Breast Cancer Centre (IBCC), Dr Javier Cortes as he discusses: (0:30) What neoadjuvant therapy is, and why it's used throughout breast cancer treatment. (1:52) The new drugs and treatment combinations that are currently being explored in the neoadjuvant setting. (3:01) How neoadjuvant therapy has evolved in the last decade. (3:50) The biggest benefits of giving therapy before surgery rather than after. Tune in for a deep dive into this important research. ⁠⁠⁠Donate to Support Life-Saving Research⁠⁠⁠ Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠ Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠ Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠ Guest: Medical Oncologist, Dr Javier Cortes, from Barcelona. Thank you for listening! If you found this episode valuable, please share it with your loved ones and help spread awareness about neoadjuvant therapy.

Next Gen Oncology: Insights for Trainees and Early-Career Clinicians Are you a trainee or early career professional in oncology looking to connect, learn, and grow? In this episode, we highlight the Trainee and Early Career Day at the Breast Cancer Trials Annual Scientific Meeting. A unique opportunity to network with peers, gain insights from leading researchers, and kickstart your professional development in the field of breast cancer research. Hear from Breast Cancer Trials Clinical Fellow, Dr Michelle Li, and former Fellow Dr Adam Ofri as they discuss: (0:26) What the Trainee and Early-Career Day is, and who it is aimed at. (2:38) What you can expect from attending the Trainee and Early-Career Day. (4:04) How this session will help those who are starting out in breast cancer research or clinical practice. (6:04) Why it's so important that the next generation of researchers and clinicians become involved with Breast Cancer Trials. Tune in for a deep dive into this important topic. Donate to Support Life-Saving Research⁠⁠⁠ Like this episode? ⁠⁠⁠Find more Breast Cancer Trials Podcast Episodes here⁠⁠⁠ Follow Breast Cancer Trials on Social Media: Instagram:⁠ ⁠⁠@breastcancertrials⁠⁠⁠ Facebook:⁠ ⁠⁠Breast Cancer Trials⁠⁠⁠ LinkedIn: ⁠⁠⁠Breast Cancer Trials⁠⁠⁠ X: ⁠⁠⁠@BCTrialsANZ⁠⁠⁠ Guests: Medical Oncologist, Dr Michelle Li, and Breast Surgeon, Dr Adam Ofri. Thank you for listening! If you found this episode valuable, please share it with your colleagues. The Trainee and Early-Career Day is a free event designed for those in the early stages of their careers in medical, radiation, or surgical oncology. This multi-disciplinary event features expert presentations, MDT panel discussions, and valuable networking opportunities with leading researchers and international speakers.