<p>This week we're doing something a little bit different on Movers &amp; Shakers. We're joined in the pub by Dr Jonathan Sackner-Bernstein, a distinguised American cardiologist with a controversial idea: that Parkinson's might be caused by too much, rather than too little, dopamine. Sackner-Bernstein's ideas call into question the underlying assumptions of the condition and have been refuted by many of his colleagues. But the debate is worth having – not least as the opposition is eloquently represented by Dr Kit Wu – because it shows just how much we still don't understand about PD, dopamine, and the human brain.</p><br><p><em>Movers &amp; Shakers</em> is brought to you in partnership with <a href="https://cureparkinsons.org.uk/" rel="noopener noreferrer" target="_blank">Cure Parkinson's</a>.</p><br><p>Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.</p><p>Produced and edited by Nick Hilton for Podot.</p><p>Sound mixing by Ewan Cameron.</p><p>Music by Alex Stobbs.</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>