One in five pediatric hospital deaths is linked to sepsis — a statistic that has driven decades of research and is now reshaping clinical guidelines worldwide. With the 2026 enhanced guidelines just published, there's no better time to dig into what the science is telling us. We're joined by Scott L. Weiss, MD, MSCE, Division Chief of Critical Care Medicine and Vice-Chair for Research at Nemours Children's Health — and co-author of both the 2020 and 2026 guidelines — to walk us through the research building a clearer, more consistent approach to recognizing and treating pediatric sepsis, and what it means for children and the clinicians who care for them.Watch the episode on YouTube.Learn more about pediatric research at Nemours.Featuring: Scott L. Weiss, MD, MSCE, Division Chief, Critical Care Medicine; Vice‑Chair for Research, Department of Pediatrics, Nemours Children’s HealthHost/Producer: Carol VassarViews expressed by guests do not necessarily reflect the views of the host or management.  Subscribe, review or let your voice be heard at NemoursWellBeyond.org.