<p>In this episode, Joris Poort, CEO and founder of Rescale, shares his personal journey on founding Rescale as well as his thoughts on the future of CAE. He discusses the challenges of introducing HPC to the cloud market, the traits that make successful founders, and the importance of perseverance and execution in entrepreneurship. Joris reflects on the early days of Rescale, the significance of early investors, and the evolving landscape of cloud computing and AI integration in engineering. The conversation highlights the complexities of transitioning to cloud solutions and the future potential of HPC in various industries. In this conversation, Joris discusses the transformative impact of AI on engineering, particularly in the context of inference, simulation, and automation. He emphasizes the importance of efficiency in engineering processes and how AI can significantly reduce the time required for complex simulations. The discussion also touches on the cultural shifts within organizations as they adapt to AI technologies, the potential for AI surrogates to revolutionize engineering practices, and the challenges of closing the sim-to-real gap. Joris offers insights for aspiring founders, encouraging them to pursue meaningful work that can drive innovation and societal progress.<br/><br/>Chapters<br/><br/>00:00 Introductions<br/>03:30 The Genesis of Rescale: A Cloud Computing Journey<br/>05:21 From Engineering to Entrepreneurship: The Leap of Faith<br/>09:28 Traits of a Successful Founder: Courage and Perseverance<br/>14:51 Tactical Steps to Startup Success: Building from the Ground Up<br/>22:10 Milestones and Breakthroughs: The Early Days of Rescale<br/>30:54 Navigating Challenges: The Role of Cloud Providers in HPC<br/>35:24 The Intersection of HPC and AI Training<br/>37:05 Cloud vs On-Premise: The Cost Debate<br/>39:54 Complexities of HPC in Enterprises<br/>42:27 The Slow Shift to Cloud Adoption<br/>44:34 Optimizing Workloads with Rescale<br/>46:50 Usability Challenges in Enterprise Software<br/>48:32 The Rise of Neo Clouds and Competition<br/>51:18 Speed and Efficiency in AI Training<br/>54:34 AI&apos;s Transformative Impact on Engineering<br/>58:54 The Future of AI Surrogates in Design<br/>01:03:28 Agentic AI: The New Paradigm in Engineering<br/>01:14:21 Solving Real Business Problems<br/>01:19:26 The Impact of AI on Engineering<br/>01:22:27 Innovation in Aerospace and Beyond<br/>01:25:19 Cultural Change in Organizations<br/>01:28:34 The Future of AI and Engineering<br/>01:39:09 Advice for Aspiring Founders<br/><br/>Keywords<br/><br/>HPC, cloud computing, startup journey, Rescale, entrepreneurship, AI, technology, innovation, engineering, business, AI, engineering, inference, simulation, automation, digital twin, innovation, aerospace, machine learning, technology</p>