The Oprah Podcast
The Oprah Podcast

The Oprah Podcast

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The Oprah Podcast is home to all-new conversations featuring Oprah Winfrey and today’s foremost thought leaders, global newsmakers, best-selling authors, visionaries and cultural changemakers. Exploring timely themes, including happiness, resilience, consciousness and connection, the weekly series aims to help listeners on their journey to lead their best life. Oprah talks to people about what matters most to them in this moment. She also features conversations with authors chosen for The Oprah Book Club.

Recent Episodes

The Co-Founders of Claude AI Tell Oprah About the Impact Artificial Intelligence Has on Your Life
MAY 19, 2026
The Co-Founders of Claude AI Tell Oprah About the Impact Artificial Intelligence Has on Your Life
The siblings and co-founders of Claude AI, the CEO, Dario Amodei, and the President, Daniela Amodei, sit down with Oprah for an in-depth discussion on Artificial Intelligence and its profound impact on all of us. Anthropic is one of the largest tech companies leading AI development including their enormously popular chatbot assistant Claude. Dario and Daniela discuss the ethical responsibility and moral questions that come with creating advanced A.I., their new model Mythos and share their thoughts around government regulation. They talk about the potential risks and benefits of A.I. in everyday lives, the impact on jobs and how it will affect children. The Amodei siblings also explain their headline-making refusal of the Pentagon’s request to remove guardrails from Claude and the behind-the-scenes discussions that helped shape their decision. 00:00:00 - Welcome Daniela and Dario Amodei, founders of Anthropic 00:01:47 - Dario on human extinction 00:04:40 - What is the AI race 00:08:00 - Athropic’s safety concerns 00:09:26 - Why they are a public benefit corporation 00:11:20 - How the siblings formed Anthropic 00:13:00 - Can AI be created responsibly 00:14:12 - Benefits and the harms 00:18:52 - People falling in love with AI 00:20:30 - Claude and underage users 00:22:18 - How Claude does not incentivize users 00:28:33 - Anthropic’s refusal to remove guardrails 00:35:10 - Hard decisions they have had to make 00;38:35 - What regulation should look like 00:40:45 - Should people view AI negatively? 00:43:00 - The AI problem to solve 00:48:20 - Men use AI more than women 00:49:30 - What is Mythos 00:53:20 - Does this keep them up at night? 00:54:15 - What keeps ego in check 00:58:20 - Will they get this right? 00:59:15 - Are there others doing this responsibly? 01:03:25 - What is the meaning of a well-lived life? Follow Oprah Winfrey on Social: https://www.instagram.com/oprahpodcast/ https://www.facebook.com/oprahwinfrey/ Listen to the full podcast: https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLI https://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381 Learn more about your ad choices. Visit megaphone.fm/adchoices
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70 MIN
Oprah and the Artemis II Crew: To the Moon and Back
MAY 12, 2026
Oprah and the Artemis II Crew: To the Moon and Back
After their extraordinary, history-making trip around the moon, Oprah has an in-depth conversation with the crew of Artemis II: Commander Reid Wiseman, Pilot Victor Glover, Mission Specialists Christina Koch and Jeremy Hansen. From launch to landing, the Artemis II astronauts captured the world’s attention while offering a message of unity and hope from space. The crew shares how they were transformed after spending more than nine days traveling farther into space than any human being has ever been and how seeing the Moon and Earth from space changed their perspectives on life itself. Oprah talks to the astronauts about their jaw-dropping photographs, plus the emotional impact and iconic moments they experienced. They’ll also talk about what it was like to train together for years, the conversations with family about putting their lives at risk, and the stellar team on the ground that guided the mission. Their outstanding character, indomitable spirits and remarkable camaraderie shine through. 00:00:00 - Welcome the crew of Artemis II 00:03:40 - Re-entry to regular life 00:07:00 - The journey back to earth 00:09:40 - Life-altering experience 00:10:50 - How they were selected for Artemis II 00;12:48 - Naming the moon crater 00:17:02 - Watching the Earth set 00:19:50 - Talking to the Chaplain upon landing 00:21:20 - A defining moment 00:24:10 - Piloting Artemis II 00:25:20 - Being at ease with not knowing 00:25:50 - Is there other life out there? 00:28:20 - Being comfortable with being uncomfortable 00:33:30 - The crew was not ready to return 00:34:30 - Christina Koch’s message to girls 00:36:20 - Staying humble 00:40:00 - Discussing death with family 00:44:00 - Discussing death with the crew 00:47:30 - Suits can keep you alive for 6 days 00:50:04 - Training not to panic 00:54:50 - Representing humans in space 00:58:30 - In the hatch after landing 00:59:58 - Message from Reid’s daughter 01:01:40 - The guilt of pursuing your dream 01:03:40 - What they want to share with the world Follow Oprah Winfrey on Social: https://www.instagram.com/oprahpodcast/ https://www.facebook.com/oprahwinfrey/ Listen to the full podcast: https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLI https://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381 Learn more about your ad choices. Visit megaphone.fm/adchoices
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71 MIN
Douglas Stuart: “John of John” | Oprah’s Book Club
MAY 5, 2026
Douglas Stuart: “John of John” | Oprah’s Book Club
As part of the 30th anniversary of Oprah’s Book Club, Oprah picks her 123rd selection: John of John by celebrated Scottish author Douglas Stuart. His other novels include Young Mungo and Shuggie Bain which won the prestigious Booker Prize in 2020. John of John is set in a small, fictional farming and textile town, Falabay, on an isle off northern Scotland where everybody knows everyone’s business. The story centers around three generations living under the same roof: a father, his son and the son's grandmother. The central theme to this enthralling book is the secrets these three so desperately hold on to: secrets from each other, from their neighbors and from the church. A love story at its heart, Douglas Stuart tells Oprah how he spent six years writing this book, spending 16 weeks researching the Outer Hebrides Isles on the northwest coast of Scotland talking to local people who inspired his 26 supporting characters. Oprah and Douglas Stuart are joined by an audience in New York City who enthusiastically read the book and have questions for the author. BUY THE BOOK! https://groveatlantic.com/book/john-of-john/ 00:00:00 - Welcome Douglas Stuart, author of “John of John” 00:03:01 - The setting of the book 00:04:05 - Where he found this story 00:07:30 - What Douglas needed to learn to write “John of John” 00:09:20 - Douglas describes “John of John” 00:11:43 - Oprah compares the book to Heated Rivalry 00:13:30 - An unexpected love story 00:17:40 - The conflict between father and son 00:20:40 - His writing process 00:25:55 - Father and gay son on “John of John” 00:30:30 - How man found acceptance of his son 00:34:20 - Feeling seen in a novel 00:38:27 - What Douglas wants the reader to feel 00:44:50 - Masculinity and the patriarchy 00:46:10 - The experience of growing up gay 00:47:20 - The end of the novel Follow Oprah Winfrey on Social: Instagram Facebook TikTok Listen to the full podcast: Spotify Apple Podcasts #oprahsbookclub Learn more about your ad choices. Visit megaphone.fm/adchoices
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51 MIN
Dog Behavior Explained: Scientist Alexandra Horowitz Reveals Your Dog's Mind to Oprah
APR 28, 2026
Dog Behavior Explained: Scientist Alexandra Horowitz Reveals Your Dog's Mind to Oprah
One of the great joys of Oprah’s life has been her dogs – she’s loved 21 one of them! For all the dog lovers, have you ever wondered what’s really happening inside the mind of your dog or how they experience the world? Oprah talks with canine cognitive scientist and New York Times bestselling author Alexandra Horowitz, whose groundbreaking book Inside of a Dog has transformed how we understand our dog companions. From the astonishing power of a dog’s nose to how they interpret our words, emotions and intentions Dr. Horowitz reveals what life looks like from a dog’s point of view. She also explores how dogs form memories, how they learn and solve problems and why their low-to-the-ground perspective influences everything, from how they experience sound and scent, to how they navigate the concept of time in a human world. Oprah and Alexandra also take questions from our listeners like: Do dogs feel anxious when we leave them alone? Can they form deep soul bonds with their humans? What do they understand about aging, illness and the end of life? The episode also checks in with a passionate dog lover whose social media mission has helped rescue hundreds of senior dogs, giving senior pups a second chance with a family. This episode is presented by our fantastic partners at The Farmer’s Dog. Their real, human-grade food has been clinically shown to help dogs age well, so you can have more good years together. Visit https://www.thefarmersdog.com/oprahpodcast for more. BUY THE BOOK! https://www.simonandschuster.com/books/Inside-of-a-Dog/Alexandra-Horowitz/9781416583431 00:00:00 - Welcome Alexandra Horowitz, author of “Inside of a Dog” 00:05:22 - Do dogs have intelligence like humans? 00:06:50 - Their most important sense 00:08:40 - Detecting diseases and emotions 00:11:50 - Dogs track our movements 00:13:10 - What your dog remembers 00:17:30 - Do dogs feel a soul connection? 00:21:40 - Having a dog changed her life 00:22:30 - Do dogs have a concept of time? 00:27:00 - Showing your dog you are boss is harmful 00:30:30 - Do dogs get bored? 00:32:40 - Do dogs understand when it's their time? 00:34:40 - How do humans know when it's time? 00:37:28 - Meet Steve who adopts senior dogs 00:39:00 - Do dogs know their name? 00:48:23 - Adopting older dogs 00:49:38 - What Alexandra wishes people knew about dogs Follow Oprah Winfrey on Social: https://www.instagram.com/oprahpodcast/ https://www.facebook.com/oprahwinfrey/ Listen to the full podcast: https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLI https://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381 Learn more about your ad choices. Visit megaphone.fm/adchoices
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56 MIN
Start with Yourself: A New Vision for Work & Life with Emma Grede and Oprah
APR 21, 2026
Start with Yourself: A New Vision for Work & Life with Emma Grede and Oprah
Emma Grede has become one of the most influential voices in modern business. She is best known as a founding partner of SKIMS, co-founder and CEO of the clothing brand Good American, her podcast Aspire with Emma Grede and as the first Black female investor on ABC’s hit show Shark Tank. She is helping redefine what success looks like for a new generation of women. In this conversation with Oprah, Emma dives into her first book Start With Yourself: A New Vision for Work and Life sharing the mindset behind her rise from a young girl in East London to a global business leader. Drawing on the lessons in her book, Emma opens up about radical self-accountability, the power of discipline and why success starts from within. She also shares her bold perspectives on work-life balance, motherhood without guilt and why women must get comfortable putting money and ambition at the forefront. Plus, we hear from twin sisters who turned a simple idea into a hundred-million-dollar business after making a deal with Emma on Shark Tank. BUY THE BOOK! Emma Grede "Start with Yourself" https://www.simonandschuster.com/books/Start-With-Yourself/Emma-Grede/9781668085486 00:00:00 - Welcome Emma Grede author of “Start with Yourself” 00:04:18 - Emma knew she needed to change 00:06:10 - Realizing what you don’t want 00:08:35 - How Emma changed her life 00:13:45 - Radical ownership and real barriers 00:15:10 - We need more women in power 00:19:00 - Career and motherhood 00:20:20 - We put too much pressure on moms 00:22:50 - Truth vs. emotions in business 00:24:22 - Mistakes Emma made 00:27:00 - Emma and Skims 00:27:50 - Building from purpose vs. ego 00:31:00 - Emma funded this on Shark Tank 00:36:00 - Importance of mentorship 00:38:20 - When to scale a small business 00:39:30 - The most important question 00:42:20 - What does self-care look like? 00:43:30 - Meditation practice 00:46:00 - Emma on life being magic 00:49:30 - Overcoming comparison 00:51:00 - Why she wrote the book 00:52:40 - Dyslexia is a superpower 00:54:30 - Is every woman meant for business? 00:56:30 - A well-lived life Cakes Body https://cakesbody.com/ Follow Oprah Winfrey on Social: https://www.instagram.com/oprahpodcast/ https://www.facebook.com/oprahwinfrey/ Listen to the full podcast: https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLI https://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381 Learn more about your ad choices. Visit megaphone.fm/adchoices
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62 MIN