Episode 40: Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

DEC 31, 202532 MIN
Concentrating on Chromatography

Episode 40: Mass Spectrometry, Surface Sampling and Dried Matrix Spots - Greener Chemistry and 3D Printing

DEC 31, 202532 MIN

Description

<p>In this episode, we interview Daniel Reddy, 2025 CAS Future Leader and PhD candidate at Queen&#39;s University, about his groundbreaking research on automated mass spectrometry and dried matrix spots (DMS).Dan&#39;s work combines computer vision, 3D printer automation, and laser micromachining to revolutionize sample preparation—reducing CO₂ emissions by 28-fold and organic solvent use by 21-fold compared to traditional methods.What You&#39;ll Learn:How to give a mass spectrometer &quot;sight&quot; and &quot;taste&quot; using computer vision and the LMJ-SSP (Liquid Microjunction Surface Sampling Probe)The breakthrough technology behind Surface Energy Traps (SETs) for confining liquid droplets on paper substratesWhy dried matrix spots eliminate the need for cold-chain shipping and enable analysis of blood, urine, and saliva samples via standard mailHow DIY chemists are hacking 3D printers to build cost-effective autosamplers (replacing $10K+ systems)The role of green chemistry and systems thinking in modernizing analytical methodsWhy interdisciplinary collaboration (chemistry + computer science) is critical to innovationKey Topics:Dried Matrix Spots (DMS) for automated sample prepLaser-micromachined Surface Energy TrapsDirect surface sampling mass spectrometrySustainability in analytical chemistry3D printer customization for laboratory automationThe importance of science communication and community outreachGuest Background:Dan Reddy is a PhD candidate in the Department of Chemistry at Queen&#39;s University and a recipient of the NSERC Vanier Canada Graduate Scholarship. He was recently named one of the top 35 early-career scientists globally in the 2025 CAS Future Leaders program.Relevant for:Analytical chemists and mass spectrometry practitionersLab managers seeking sustainable and cost-effective sample prep solutionsResearchers interested in green chemistry and automationDIY enthusiasts and makers interested in laboratory innovationStudents pursuing careers in analytical chemistry</p>