Migraines are not “just headaches”! In this episode, Dr Amir Khan and Cherry Healey look at what’s really happening inside your brain during a migraine, from the trigeminal nerve to the brain chemical CGRP that can trigger intense pain, nausea, and visual disturbances. Find out why women are three times more likely to experience migraines than men. What role hormones and oestrogen play, especially around your period and during perimenopause. And when does a migraine become something more serious, like a “thunderclap headache” that needs urgent medical attention. We've partnered with ⁠Randox Health⁠. Take their Everyman and Everywoman health check at https://randoxhealth.com/en-GB/ just use the code NAN15 to save 15% off their health checks. Results will arrive in just 2 hours from your sample arriving at the lab. Download SAILY in your app store and use our code nan at checkout to get an exclusive 15% off your first purchase! For further details go to https://saily.com/nan Have an itchy, irritated scalp? Polytar, trusted by doctors for over 60 years, can help treat dandruff, psoriasis and seborrhoeic dermatitis at the source. Head to polytar.co.uk and use code Appointment10 for 10% off. Always Read the Label. Have a question, feedback, or want to suggest a topic? Email: [email protected] The content of No Appointment Necessary is for general information, it's not a substitute for a personalised medical assessment. Always consider your own medical history and personal circumstances before acting on any health information. A Made You Look Studios Production. Developed and produced by James Carpenter & Jo Scarratt-Jones Learn more about your ad choices. Visit podcastchoices.com/adchoices