Modern science has given us the ability to edit our genes, life-saving vaccines, and glimpse the origins of the universe. But is the same system holding itself back? Critics argue that the pressure to publish and fierce competition for funding rewards safe, incremental work over bold thinking. Others see a system still capable of paradigm-shifting discoveries — one where global collaborations and long-term thinking motivate scientists to pursue grand, ambitious ideas. Now we debate: Is the Scientific Enterprise Too Risk-Averse?  This debate was produced in partnership with the Stavros Niarchos Foundation (SNF) Agora Institute at Johns Hopkins University, as part of The Hopkins Forum series. Arguing Yes:  Tyler Cowen, Author of "The Great Stagnation"; Economics Professor at George Mason University; Founder of Emergent Ventures; Host of "Conversations with Tyler" podcast   Brandon Ogbunu, Computational Biologist; Associate Professor of Ecology and Evolutionary Biology at Yale University; Professor at the Santa Fe Institute  Arguing No:   Kate Biberdorf (“Kate the Chemist”), Professor for the Public Understanding of Science and the Department of Chemistry & Biochemistry at the University of Notre Dame; Science Entertainer  The Honorable Sethuraman Panchanathan, 15th Director of the National Science Foundation; University Professor of Technology and Innovation and Foundation Chair at Arizona State University  Emmy award-winning journalist John Donvan moderates  Join the conversation on Substack—share your perspective on this episode and subscribe to our weekly newsletter for curated insights from our debaters, moderators, and staff.  Follow us on YouTube, Instagram, LinkedIn, X, Facebook, and TikTok to stay connected with our mission and ongoing debates.  Learn more about your ad choices. Visit podcastchoices.com/adchoices