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DEC 11, 2025
AMD CEO Lisa Su Isn’t Afraid of the Competition
Last week, some of the most forward-thinking minds in tech, culture, and politics came together for WIRED’s Big Interview event — a series of live, in-depth conversations with industry leaders. To kick off the event, Lauren sat down with AMD’s CEO Lisa Su. In today’s episode, Mike and Lauren sit down to discuss the key ideas that came up during the interview, as well as the other conversations that caught everyone’s attention during the event.
Articles mentioned in this episode:
AMD CEO Lisa Su Says Concerns About an AI Bubble Are Overblown | WIRED
Can AI Look at Your Retina and Diagnose Alzheimer’s? Eric Topol Hopes So | WIRED
San Francisco Mayor Daniel Lurie: ‘We Are a City on the Rise’ | WIRED
Watch the Highlights From WIRED’s 2025 Big Interview Event Right Here | WIRED
Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.
47 MIN
DEC 9, 2025
BIG INTV: San Francisco Mayor Daniel Lurie: ‘We Are a City on the Rise’
Since taking office, San Francisco’s mayor has been on a quest to revitalize the city and increase public safety. He’s also kept the National Guard out—with a little help from some very powerful friends. Katie sat down with Mayor Lurie (who took off his shoes) on stage at WIRED’s Big Interview Event in San Francisco.
Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.
31 MIN
DEC 5, 2025
WIRED Roundup: DOGE Isn’t Dead, Facebook Dating Is Real, Amazon AI Releases
In today’s episode, Zoë is joined by WIRED’s Leah Feiger to discuss five stories you need to know about this week — from how Amazon is trying to catch up in the AI race, to why Facebook Dating is more popular than ever. Then, they dive into how despite recent reports claiming that DOGE is over, its operatives are still working across federal agencies.
Articles mentioned in this episode:
Amazon Has New Frontier AI Models—and a Way for Customers to Build Their Own | WIRED
Poems Can Trick AI Into Helping You Make a Nuclear Weapon | WIRED
Who the Hell Is Actually Using Facebook Dating? | WIRED
Sex Workers Built an ‘Anti-OnlyFans’ to Take Control of Their Profits | WIRED
DOGE Isn’t Dead. Here’s What Its Operatives Are Doing Now | WIRED
Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.
25 MIN
DEC 4, 2025
What Happens When Your Coworkers Are AI Agents
This year, AI agents have been at the forefront of tech companies' ambitions. OpenAI’s Sam Altman has often talked about a possible billion-dollar company being spun up with just one human and an army of AI agents. And so last summer, journalist Evan Ratliff decided to try to become that unicorn himself — by creating HarumoAI, a small startup that’s made up of AI employees and executives. Mike and Lauren sit down with Evan to discuss how it’s going, and the current promises and realities of AI agents.
Articles mentioned in this episode:
All of My Employees Are AI Agents, and So Are My Executives | WIRED
AI Agents Are Terrible Freelance Workers | WIRED
Who’s to Blame When AI Agents Screw Up? | WIRED
Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.
36 MIN