This Week in Startups
This Week in Startups

This Week in Startups

Jason Calacanis

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Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Recent Episodes

Why Your Company Should Own Its AI Model | E2278
APR 21, 2026
Why Your Company Should Own Its AI Model | E2278
This Week In Startups is made possible by:Quo - https://quo.com/TWiST Vanta - https://vanta.com/twist Pilot - https://pilot.com/twist Plaud - https://Plaud.ai/twistToday’s show:*Eragon CEO Josh Sirota believes that you should “own your intelligence.” He demos a live enterprise AI operating system connecting email, Slack, calendar, and financial data into a single agentic layer that’s pre-trained to understand any business inside and out.PLUS we’ve got IONA Drones founder Etienne Louvet, a first look at Moonshot’s Kimi K2.6, and a brand new Off Duty with JCal and Lon.FULL SHOW NOTES ON NOTION: https://thisweekinstartups-docket.notion.site/TWiST-2278-SHOW-NOTES-34872ca918e380bd9c71e684ce2db7c9?source=copy_linkGuests :Eragon: https://eragon.aiJosh Sirota on X: https://x.com/joshua_sirotaIONA: https://ionadrones.com/Etienne Louvet on X: https://x.com/etienneldvaRelevant LinksEragon Seed Round coverage: https://techcrunch.com/2026/03/18/this-startup-wants-to-make-enterprise-software-look-more-like-a-prompt/Neurometric: https://www.neurometric.ai/Ollama model: https://ollama.com/Orange Slice: https://www.orangeslice.ai/Corgi Insurance: https://www.corgi.insure/Slash Financial: https://www.slash.com/The Syndicate: https://thesyndicate.com/FAA Part 108 Explained: https://pilotinstitute.com/part-108-explained/Zipline: https://www.zipline.com/Google Wing: https://wing.com/Joby Aviation: https://www.jobyaviation.com/Enterprise Ireland: https://www.enterprise-ireland.com/Éire Composites: https://www.eirecomposites.com/Kimi K2.6 blog post: https://www.kimi.com/blog/kimi-k2-6Kimi K2 series on GitHub: https://github.com/moonshotai/Kimi-K2NVIDIA GB300 NVL72 work station: https://www.nvidia.com/en-us/data-center/gb300-nvl72/Timestamps:0:00 Josh from Eragon AI joins the show2:01 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!5:07 Why founders should own and control their data sets8:33 What is a "company world model?"9:48 Quo (formerly OpenPhone) - Quo gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at https://quo.com/TWiST11:32 Eragon demo15:55 Giving agents their own bank accounts19:07 Inside Eragon's first partnerships20:14 Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist25:50 How does Eragon make money?29:11 Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year.39:33 Etienne Louvet of Iona Drones joins the show42:37 What is FAA's Part 108?47:13 How innovation in drones impacts the aviation industry50:26 Working with Enterprise Ireland58:28 Jason attended the Breakthrough Awards1:04:10 Doug Liman's AI-powered "Bitcoin" movie1:09:09 "Love Story" on FX and "Dust Bunny" on HBO Max1:13:10 Jason's love of tinned fishSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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76 MIN
3D-Printed Homes for $99K: ICON’s Jason Ballard on the future of housing | E2277
APR 18, 2026
3D-Printed Homes for $99K: ICON’s Jason Ballard on the future of housing | E2277
This Week In Startups is made possible by:IM8 Health - https://IM8health.com/twist Grasshopper Bank - https://grasshopper.bank/twist Northwest Registered Agent - https://northwestregisteredagent.com/twist Plaud - https://Plaud.ai/twistToday’s show:Is 3D printing the key to not just solving the housing crisis but bringing us all into a more beautiful and utopian future? ICON founder Jason Ballard thinks so. His company is already building homes for the unhoused and delivering barracks to Fort Bliss at half the cost and a fraction of the time. On TWiST, he tells us space construction is also on the agenda.Explore the potential for robot-powered concrete construction can help build cheap homes for the unhoused, modernize our military infrastructure, AND colonize the solar system in this exclusive interview.Then Seby Rubino of Resi Labs demos his real estate “Oracle,” which can guess the price of any home with 98% accuracy… for just fractions of a penny.PLUS Jason tells a story of the rare founder who got one over on him, and why he’s moving away from vengeance and anger and into love and acceptable.AND we’ve got more JCal and Lon recommendations in a brand-new Off Duty.Guests :Jason Ballard: https://x.com/JasonDBallardICON: https://www.iconbuild.com/ICON on X: https://x.com/ICON3DTechSeby Rubino: https://x.com/SebyverseResi Labs: https://portal.resilabs.ai/Timestamps:0:00 Intro + "balance the ledger" tease1:10 Jason Ballard (ICON) joins — 3D-printed homes + defense (ICON Prime)5:18 Housing basics: commutes, quality of life, "food/water/shelter"7:15 ICON Prime: military construction, survivability, speed, supply chain10:08 IM8 Health: Start feeling like your best self every day. Go to https://IM8health.com/twist and use the code TWiST to get a free welcome kit, five free travel sachets, and 10% off your order.11:35 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!12:43 Fort Bliss barracks: 10 in 6 months, half the cost; blast/ballistics20:23 Beautiful + dignified housing: Community First Village; "where's the floor?"20:29 Grasshopper Bank: Time is money. Don't waste either. Go to https://grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account.30:10 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://www.northwestregisteredagent.com/twist37:27 Audience Q&A: longevity/cracking; plumbing + electrical41:33 ICON Titan printer + channel partners; hiring pitch45:47 Sebi Rubino (Rezzy Labs) joins — BitTensor subnet 46 real estate pricing51:18 Tau/BitTensor explained: subnet competitions, "narrow intelligence"59:15 Rezzy demo: portal + pricing engine; customers + business model1:07:49 "Got shivved for 500k" story: acquisition, investors get zero1:20:36 Bounties: annotated.com + AI sidebar + headless CMS on BitTensor1:31:10 Off-duty: View Buds (camera earbuds) + use cases1:38:13 Off-duty: Anker charger/cable/battery "trio"1:41:12 Off-duty: The Audacity (AMC) quick review1:46:43 Wrap-up + secret TWiST group chat on XSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanis
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107 MIN
This 22-Year-Old Built TikTok for Mobile Games, and It’s Growing Fast | E2276
APR 15, 2026
This 22-Year-Old Built TikTok for Mobile Games, and It’s Growing Fast | E2276
This Week In Startups is made possible by:LinkedIn Jobs - LinkedIn.com/twist Every.io - every.io Render - render.com/twistToday’s show:*Imagine scrolling through mobile games the way your flip through your TikTok feed. What if you could build your own game in 90 seconds and share it with the world? That’s what over 100,000 users are enjoying right now on Nanogram.On TWiST, we meet the co-founders: 22-year-old CEO Albert Brotherton and 24-year-old CTO Boris Radilov. They demo the app for us on the air, and Jason immediately spies the potential. Power users are playing 25+ games per session already.We’re digging into the co-founders future plans, including the potential for ads in your game feed, in this TWiST exclusive.PLUS domestic helper bots are here. NEO from 1X Technologies can do the laundry, open the door for guests, and even read and understand Post-It Note messages.Alex talks with CEO Bernt Børnich about building the safety-first 66-lb humanoid, why world models are so crucial for training robots in particular, and why homes are even tougher places for robots to navigate than factory floors.Timestamps:0:59 Nanogram co-creators Albert and Boris join the show3:42 Nanogram is TikTok for casual AI-generated games4:27 Building Nanogram with Google Gemini5:49 Draper and Associates: https://www.draper.vc6:11 Integrating ads into the game feed7:36 Roblox: https://www.roblox.com World of Warcraft: https://worldofwarcraft.blizzard.com8:25 Building in New York9:07 Jason is obsessed with the Staples Baddie https://www.tiktok.com/@blivxx10:12 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist20:36 Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit https://every.io21:40 1X CEO and founder Bernt Børnich joins the show https://x.com/BerntBornich22:31 Designing robots to actually live around people26:30 Teaching NEO about movement in the physical world29:00 TechCrunch coverage: https://techcrunch.com/2026/01/13/neo-humanoid-maker-1x-releases-world-model-to-help-bots-learn-what-they-see/29:58 Render: Find out why 5 million developers are already using the all-in-one cloud platform, Render. Go to https://render.com/twist and apply for the Render Startup Program to get $500-$100,000 in free credits, depending on your stage and backers.31:04 Moving beyond training data to true general intelligence33:17 Ensuring NEO pursues the safest possible path34:19 Why are world models so important?41:51 1X World Model Challenge on GitHub: https://github.com/1x-technologies/1xgpt45:14 Robots need to train on a lot of data… Where does it all come from?50:14 Manufacturing NEO from raw materials in San Carlos56:32 Robots building robotsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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62 MIN
Bittensor’s (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275
APR 14, 2026
Bittensor’s (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275
This Week In Startups is made possible by:Sentry - https://sentry.io/twist Deel - https://deel.com/twist Netsuite - https://netsuite.com/twist Plaud - https://Plaud.ai/twistToday’s show:*TAO just had its worst week since launch. One of Bittensor’s most prominent subnet operators allegedly dumped $10 million in tokens and walked away. We’re digging into what we know, how this could change the Bittensor community… and why dedicated builders still believe in this ecosystem.Jason and Lon are joined by Stillcore Capital Partner Mark Jeffrey to break down the Covenant AI and Templar controversy in real time. Then they’re joined by three prominent subnet founders: Ken Miyachi of BitMind (Subnet 34) and Will Squires of Steffen Cruz of MacroCosmos (which owns Subnets 1, 9, and 13). Together, they’re investigating how Bittensor incentives work, how real products are still emerging from the TAO ecosystem, and what governance fixes could arise to prevent the next (alleged) rug pull.Timestamps:0:00 Mark Jeffrey joins the show! https://x.com/markjeffrey2:18 How Mark Jeffrey learned about Bittensor. https://bittensor.com/6:17 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!7:22 Mark Jeffrey's Bittensor investments. https://stillcorecapital.com/9:25 Check out our discussion with Nova: https://youtu.be/gjRt4eUyiYc?si=HopdmmSarxECark110:16 Sentry - New users can get $240 in free credits when they go to https://sentry.io/twist and use the code TWIST10:41 Check out Ridges! https://www.ridges.ai/11:53 How trading alpha tokens works on Bittensor12:44 Subnet drama: what happened? https://x.com/covenant_ai/status/204238015283195130016:01 Do subnet owners have too much power?18:33 Check out our conversation with Sam Dare (2268): https://youtu.be/TN2RmNuX4-k?si=c58Byh7Fsw1ttnAY19:10 How Sam Dare should've handled walking away (per Mark Jeffrey)20:02 Deel - Founders scale faster on Deel. Set up payroll for any country in minutes, hire anyone anywhere, get visas handled fast, and get back to building. Visit https://deel.com/twist to learn more.23:29 Who should subnets be owned by?24:02 Ken Miyachi from BitMind joins the show https://x.com/kenmiyachi30:56 Netsuite - Get the free business guide Demystifying AI at https://www.netsuite.com/twist31:06 Ken's $3M raise & investors (Arch, Canonical, Mechanism)33:18 Token vs. equity: how to think about a subnet investment.41:57 Will Squires and Stefan Kruse of MacroCosmos join the show https://x.com/willsquires https://x.com/sczsteffencruz56:29 Stefan on the Covenant drama: "disappointing, but solvable"1:02:11 Off-duty with J-Cal, Mark Jeffrey, and Lon Harris1:02:48 Bieber vs. Carpenter: does Coachella owe you a spectacle? https://www.youtube.com/watch?v=hp5O72WUqTk https://x.com/FashionXGirl_/status/20432512705095929361:15:20 Jason says Staples should pay the "Staples baddie" $1M/year https://www.tiktok.com/@blivxxSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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78 MIN
Bittensor Drama! TAO down 15%! | E2274
APR 11, 2026
Bittensor Drama! TAO down 15%! | E2274
This Week In Startups is made possible by:Pilot - https://pilot.com/TWISTSquarespace -https://squarespace.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/TWISTPlaud - https://Plaud.ai/twistCrowdHealth - ⁠https://JoinCrowdHealth.com/twist⁠Today’s show:TAO, the token associated with the Bittensor network, fell sharply last night after a major project declared it was taking its business elsewhere. Covenant AI had used Bittensor subnets 3, 39, and 89 before its abrupt and controversial decision to depart for other digital shores.Gareth Howells, a co-founder of Vidaio (Bittensor Subnet 85), joined Jason and Alex to share the community perspective regarding Covenant’s decision to leave Bittensor, a choice that was especially bitter given that its recently-released Covenant-72B model trained using the network’s decentralized capabilities was hailed at the time as a demonstration of the crypto-AI hybrid’s potential. (Covenant’s Sam Dare was a recent guest on TWiST.)Howells walked us through Vidaio’s product (AI models for high-quality video work, like upscaling) Then it was time to bring new fan-favorite Ole Lehmann on. Ole took an Andrej Karpathy concept, and turned it into a skill that you can use in either OpenClaw or Claude Cowork. GuestsOle Lehmann: https://x.com/itsolelehmannThe AI Solopreneur newsletter: https://aisolo.beehiiv.com/Vidaio: https://vidaio.io/Vidaio on X: https://x.com/vidaio_Timestamps:0:00 Drama in the Bittensor space! Was there a rugpull?1:01 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!1:47 Gareth Howells of subnet85 joins the show: https://x.com/GarethHowells9:56 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at https://northwestregisteredagent.com/TWIST11:37 Gareth reacts to the Covenant situation… Did Sam sell tokens?14:33 How VidAIo (subnet85) optimizes video as cheaply as possible. https://vidaio.io/20:06 Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/TWIST21:12 Demo: Gareth shows upscaled footage of our very own Lon Harris27:09 Who is actually doing the computing on Bittensor?28:15 How Bittensor recruits tech talent from emerging markets29:42 Pilot - Visit https://pilot.com/TWIST and get $1,200 off your first year.30:58 Jason's explains the Bittensor network. https://docs.bittensor.com/37:28 Jason addresses "pump and dump" allegations40:46 Ole Lehmann joins the show https://x.com/itsolelehmann45:31 Jason's $1,000 "bounty" for enhanced show notes49:35 Check out Ole's newsletter at aisolo.beehiiv.com !59:50 CrowdHealth - CrowdHealth lets you ditch the bureaucracy with a peer-to-peer funding platform for your healthcare. Get started for $99 per month for your first three months by using the code TWIST at https://JoinCrowdHealth.com/twist.1:00:46 Off Duty with Alex and J-Cal!1:04:46 Reacting to the Maul trailer https://www.youtube.com/watch?v=DkVepshZhGcSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
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81 MIN