<description>&lt;p&gt;Listener feedback, the huge CLOSURE-AF trial of LAAC vs best medical therapy, previews of CHAMPION AF, and the controversial ACC/AHA lipid treatment guidelines are the topics John Mandrola, MD, discusses in this week's podcast.&lt;/p&gt; &lt;p&gt;&lt;em&gt;This podcast is intended for healthcare professionals only&lt;/em&gt;.&lt;/p&gt; &lt;p&gt;To read a partial transcript or to comment, visit:&lt;/p&gt; &lt;p&gt;https://www.medscape.com/twic&lt;/p&gt; &lt;p&gt;&lt;strong&gt;I Listener Feedback&lt;/strong&gt;&lt;/p&gt; &lt;ul&gt; &lt;li&gt;&lt;strong&gt;COBRRA Trial&lt;/strong&gt; https://www.nejm.org/doi/full/10.1056/NEJMoa2510703&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;&lt;strong&gt;Closure AF published in NEJM&lt;/strong&gt;&lt;/p&gt; &lt;ul&gt; &lt;li&gt;&lt;strong&gt;CLOSURE-AF Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2513310&lt;/strong&gt;&lt;/li&gt; &lt;li&gt;&lt;strong&gt;CHAMPION AF Rationale - Watchman FLX vs DOACs in Patients With AF https://pubmed.ncbi.nlm.nih.gov/37279840/&lt;/strong&gt;&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;&lt;strong&gt;LIPID Guidelines&lt;/strong&gt;&lt;/p&gt; &lt;ul&gt; &lt;li&gt;&lt;strong&gt;ACC/AHA Joint Committee Guideline on Management of Dyslipidemia https://www.jacc.org/doi/10.1016/j.jacc.2025.11.016&lt;/strong&gt;&lt;/li&gt; &lt;/ul&gt; &lt;p&gt;&lt;em&gt;&lt;strong&gt;You may also like:&lt;/strong&gt;&lt;/em&gt;&lt;/p&gt; &lt;p&gt;The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington&lt;/p&gt; &lt;p&gt;Questions or feedback, please contact news@medscape.net&lt;/p&gt;</description>

This Week in Cardiology

Medscape

Mar 20 2026 This Week in Cardiology

MAR 20, 202635 MIN
This Week in Cardiology

Mar 20 2026 This Week in Cardiology

MAR 20, 202635 MIN

Description

Listener feedback, the huge CLOSURE-AF trial of LAAC vs best medical therapy, previews of CHAMPION AF, and the controversial ACC/AHA lipid treatment guidelines are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback COBRRA Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2510703 Closure AF published in NEJM CLOSURE-AF Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2513310 CHAMPION AF Rationale - Watchman FLX vs DOACs in Patients With AF https://pubmed.ncbi.nlm.nih.gov/37279840/ LIPID Guidelines ACC/AHA Joint Committee Guideline on Management of Dyslipidemia https://www.jacc.org/doi/10.1016/j.jacc.2025.11.016 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact [email protected]