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Clearly Hormonal
Komal Patil-Sisodia, MD
The Long Road to Diagnosis: PMOS and Mental Health
SEP 23, 202611 MIN
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Description
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In the final episode of PMOS Awareness Month, I focus on something that does not get talked about enough: the mental health toll of PMOS and the harm caused by waiting years for a diagnosis. We walk through what weight-matched studies show about depression, anxiety, and eating disorders, why so many people carry these burdens long before anyone connects them to PMOS, and what real care should look like.
In this episode
Why people with PMOS are about four times more likely to have depression and more than five times more likely to have anxiety
Why a PMOS diagnosis often comes before a new diagnosis of depression, anxiety, or sleep problems
How eating disorder risk rises with PMOS, and why it is not limited to larger bodies
How years of scattered symptoms and "it is just stress" responses make things worse
Why body image distress from visible symptoms is a real pathway to disordered eating
What good care includes: screening at diagnosis, CBT as a first step, careful medication choices, treating physical symptoms, and mind-body approaches
Timestamps
00:00 Welcome to Clearly Hormonal
01:01 PMOS Series Finale Setup
02:04 Mental Health Stats in PMOS
03:24 Eating Disorders and PMOS
04:00 Why Diagnosis Takes Years
05:37 Body Image and Visible Symptoms
06:56 What Good Care Looks Like
08:50 What This Means for You
09:51 Series Wrap Up and Resources
11:02 PMOS Mini Course Announcement
Key numbers from the episode
About 4 times more likely to have depression with PMOS, in weight-matched studies
More than 5 times more likely to have anxiety with PMOS
About 1 in 3 people with PMOS have moderate to severe depression; more than 4 in 10 have real anxiety symptoms; well under 15 percent without PMOS
About 1.5 times more likely to have an eating disorder, with the biggest increases in binge eating disorder and bulimia
The full PMOS Awareness Month series
Episode 1: What happens in PMOS after your childbearing years
Episode 2: Why PMOS gets missed in people with a normal BMI (lean PMOS)
Episode 3: Where GLP-1 medications fit into PMOS treatment
Episode 4: PMOS and mental health (this episode)
A note on support
If anything in this episode brought up something personal for you, especially around food, body image, or how you have been feeling emotionally, please do not sit with that alone. Talk to your doctor or a mental health professional. If you are in crisis in the US, you can call or text 988 at any time.
Connect
Instagram and TikTok: @drpatilsisodia
eastsidemm.com
This episode is for education and is not a substitute for individual medical advice.
Thanks for listening. Find more info about Clearly Hormonal on the website or Instagram.

