Postthrombolysis Intracranal Hemorrhage

In this episode, Sam Ashoo, MD and Dr. Syeda Maria Muzammil, MD discuss the August 2026 Emergency Medicine Practice article, Emergency Department Management of Postthrombolysis Intracranial Hemorrhage. 0:25 – Intro & sponsor message 1:18 – Guest introduction: Dr. Maria Muzammil 2:24 – Timeframe for post-thrombolysis hemorrhage & ED/ICU boarding considerations 4:46 – Thrombolysis eligibility criteria & contraindications 5:46 – Incidence rates & symptomatic vs. asymptomatic hemorrhage 7:09 – Pathophysiology & risk factors for post-thrombolytic ICH 10:18 – Combining IV thrombolysis with endovascular thrombectomy 12:33 – Post-treatment monitoring protocols & neurological exam frequency 15:02 – Differentiating hemorrhage from other causes of neurological decline 18:34 – Initial ED steps 20:35 – Heidelberg classification of hemorrhage types 21:60 – Follow-up imaging 25:27 – Treatment of confirmed hemorrhage 30:10 – Platelet transfusion guidance 32:39 – Delayed hemorrhage & treatment timing considerations 34:21 – Blood pressure management goals post-hemorrhage 37:20 – Special populations 38:48 – Summary of ED management algorithm 40:48 – Closing remarks Subscribers, take the CME test here. Emergency Medicine Residents, get your free subscription by writing [email protected]