It's Open with Ilana Glazer

Today, Ilana sits down with her brilliant and dear friend, Erica Chidi. Erica lives, works, and creates at the intersections of human health, culture, and technology. She is a full-spectrum doula, the co-founder and former CEO of the digital sexual and reproductive health platform LOOM (acquired by Perelel Health in 2024), author of NURTURE: A MODERN GUIDE TO PREGNANCY, BIRTH, EARLY MOTHERHOOD—AND TRUSTING YOURSELF AND YOUR BODY, current SVP of Brand & Editorial Content at the digital med...

Today on It’s Open, Ilana is joined by the sensational, the trailblazing, the thought leader and activist: Miss Peppermint. She was the first openly trans contestant on RUPAUL’S DRAG RACE, the first trans woman to originate a lead Broadway role for the musical HEAD OVER HEELS, is an Out Magazine’s Out100 honoree, and Pep is the biographical subject of the documentary film A DEEPER LOVE: THE STORY OF MISS PEPPERMINT. We are so proud of herrr. Peppermint and Ilana get right into it, unpacking...

Joining us today is the brilliant, noble, and hilarious Jennifer Welch — co-creator of the breakthrough political and cultural podcast I’VE HAD IT, which disrupted the political media landscape, amassing over 4.5 million followers across platforms with razor-sharp, unfiltered, anti-authoritarian critical commentary, first broadcast from the “Buckle of the Bible Belt”, Oklahoma City! Jennifer talks with Ilana about the Bible Belt’s disturbing obsession with sexual chastity and purity cu...

Anointed by Rolling Stone in 2017 as one of the 20 greatest stand-up comedians of ALL TIME, our guest today has released 12 highly acclaimed stand-up comedy specials including his most recent Drop Dead Years in 2025, has trail-blazed the podcasting genre since the launch of his Monday Morning Podcast in 2007, continues to add outstanding TV and film performances to his credentials from roles in Breaking Bad and The Mandalorian, to this year’s highly anticipated The Social Reckoning, and made ...

Today on It’s Open we are joined by one of the most popular and influential creators of infant, toddler, and early childhood educational content in the world today—with over 21 million subscribers, and over 17 billion views on YouTube—it’s the one-and-only Ms Rachel! Ilana and Rachel’s burgeoning friendship brings them together as they connect deeply about standing up and speaking out for the safety and human rights of ALL children, how compassion is awesome, and the “empathy trap” is nonsen...