Oxybutynin, Detrol, Vesicare: how do you come off a bladder pill?

Bladder anticholinergics such as oxybutynin, tolterodine (Detrol) and solifenacin (Vesicare) calm an overactive bladder by blocking acetylcholine. That is also why they can bring dry mouth, constipation, blurry vision, trouble emptying the bladder and mental fog, and why this class gets reviewed rather than renewed year after year. This episode covers what the American Geriatrics Society Beers Criteria says about oxybutynin and the wider antimuscarinic class in older adults, what the research on anticholinergics and dementia does and does not show, and which drugs in a different class work through another receptor. It also covers the practical part: why behavioral steps such as bladder training and pelvic floor exercises come first and need weeks of honest effort, what a planned step-down with your provider can look like, what a short rebound in urgency means, and what tends to improve after stopping. Full guide: How to Safely Come Off Bladder Anticholinergics. Find a provider trained in deprescribing: mydeprescriber.com/find-a-provider. The hosts are AI-generated from the written guide. Educational only, not medical advice. Never stop a medication without your provider. If you are in crisis in the US, call or text 988.