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Nice Genes!
Genome BC
It’s Prime Time: Can New Gene Editing Technologies Re-write the Future of Health?
OCT 6, 202633 MIN
/https://files.cohostpodcasting.com/cohost/b3294355-5898-49e4-8c1a-f1230920e455/shows/1ccc5639-2233-4ade-b6fd-76273b226304/episodes/089f0f9d-a1ed-4519-8296-73d404782292/e9d1863a61.jpg)
Description
Many rare genetic diseases are caused by a “typo” in our DNA. For most, fixing that spelling mistake has been out of reach. But a recent clinical trial has changed everything, opening up the door for possible cures we never thought were possible through a cutting-edge gene-editing tool called prime editing.
In this episode, Ty Sperle takes us through his own story of being cured of a rare disease called chronic granulomatous disease while his doctor, Dr. Stuart Turvey gives Kaylee the 411 on the science behind Ty’s treatment – and what it could mean for rare diseases more broadly. We also make a stop at the PrimeSight Lab, where researchers are exploring how prime editing could help bring the world into focus for people with inherited vision loss.
For a treatment that once sounded like science fiction, could prime editing be a glimpse of the future of medicine?
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Highlights
00:01 - Ty’s World-First Cure
07:11 - Inside the Prime Editing Revolution
23:43 - Can Prime Editing Restore Sight?
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Sources
First-in-world BC patient successfully treated for rare immune disease
B.C. teen cured of rare disease
Future Perspectives of Prime Editing for the Treatment of Inherited Retinal Diseases

