Pearls and Prep

💎 Go beyond the episode — study guides, psychopharm deep dives & practice questions: https://www.patreon.com/PearlsandPrep 🎁 Join as a free member to access 50 Pearls from Pearls & Prep — 50 super high-yield pearls to sharpen your practice. 📚 The 100 Psychiatric Interview Tips For Your 1st Eval E-Book is $39.99 in the shop — or get it FREE as a Boss Pearl member: https://www.patreon.com/c/pearlsandprep/shop ⭐ Enjoying the show? Please rate and review Pearls and Prep on Apple Podcasts or Spotify — it really helps! 🌐 PearlsandPrep.com — scan this episode's Street Takes card, read the deep-dive articles, and unlock the full clinical library: https://pearlsandprep.com ✉️ Questions or a case you want covered? Write to NP Z: [email protected] Atomoxetine (Strattera) and bupropion (Wellbutrin) both influence norepinephrine, ease attention difficulties, and carry no controlled-substance burden — yet they serve very different clinical purposes. This episode uses real-world psychopharmacology reasoning to compare them, so you grasp the why behind each choice rather than memorizing a list. Focused PMHNP boards prep that builds the clinical confidence to select the right non-stimulant option for the right patient. 🎧 Pearls & Prep — new episodes every Tuesday. Hosted by NP Z, Duke-trained Psychiatric Nurse Practitioner. ⚖️ Disclaimer: Pearls and Prep is an educational podcast and is not medical advice. All views expressed are exclusively those of NP Z and do not represent — and are not endorsed by — any other entity or organization. These perspectives are offered solely to build conceptual appreciation of psychiatric topics; they are not a substitute for clinical judgment, current clinical guidelines, or primary references. Always use appropriate resources and your own clinical judgment when making decisions about individual patients. Nothing in this episode creates a clinician–patient relationship. This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

💎 Go beyond the episode — study guides, psychopharm deep dives & practice questions: https://www.patreon.com/PearlsandPrep 🎁 Join as a free member to access 50 Pearls from Pearls & Prep — 50 super high-yield pearls to sharpen your practice. 📚 The 100 Psychiatric Interview Tips For Your 1st Eval E-Book is $39.99 in the shop — or get it FREE as a Boss Pearl member: https://www.patreon.com/c/pearlsandprep/shop ⭐ Enjoying the show? Please rate and review Pearls and Prep on Apple Podcasts or Spotify — it really helps! 🌐 PearlsandPrep.com — scan this episode's Street Takes card, read the deep-dive articles, and unlock the full clinical library: https://pearlsandprep.com ✉️ Questions or a case you want covered? Write to NP Z: [email protected] Asenapine (Saphris) remains one of the most overlooked second-generation antipsychotics in psychopharmacology. This episode maps exactly where it fits — bipolar I disorder, acute mania, mixed episodes, and schizophrenia — and explains why Saphris is dosed sublingually and what makes its receptor profile distinctive. You will leave understanding the why behind this SGA's niche, with sharper clinical confidence for PMHNP boards and real-world prescribing. 🎧 Pearls & Prep — new episodes every Tuesday. Hosted by NP Z, Duke-trained Psychiatric Nurse Practitioner. ⚖️ Disclaimer: Pearls and Prep is an educational podcast and is not medical advice. All views expressed are exclusively those of NP Z and do not represent — and are not endorsed by — any other entity or organization. These perspectives are offered solely to build conceptual appreciation of psychiatric topics; they are not a substitute for clinical judgment, current clinical guidelines, or primary references. Always use appropriate resources and your own clinical judgment when making decisions about individual patients. Nothing in this episode creates a clinician–patient relationship. This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

💎 Go beyond the episode — study guides, psychopharm deep dives & practice questions: https://www.patreon.com/PearlsandPrep 🎁 Join as a free member to access 50 Pearls from Pearls & Prep — 50 super high-yield pearls to sharpen your practice. 📚 The 100 Psychiatric Interview Tips For Your 1st Eval E-Book is $39.99 in the shop — or get it FREE as a Boss Pearl member: https://www.patreon.com/c/pearlsandprep/shop ⭐ Enjoying the show? Please rate and review Pearls and Prep on Apple Podcasts or Spotify — it really helps! 🌐 PearlsandPrep.com — scan this episode's Street Takes card, read the deep-dive articles, and unlock the full clinical library: https://pearlsandprep.com ✉️ Questions or a case you want covered? Write to NP Z: [email protected] When depression lifts on an SSRI but joy, motivation, and emotional range stay flat, is it residual depression or SSRI-induced emotional blunting? This episode compares bupropion (Wellbutrin) and vortioxetine (Trintellix) for exactly that stuck moment in practice. You will learn the psychopharmacology reasoning that separates the two, sharpening your differential diagnosis skills and building clinical confidence for PMHNP boards — so you understand the why before you switch. 🎧 Pearls & Prep — new episodes every Tuesday. Hosted by NP Z, Duke-trained Psychiatric Nurse Practitioner. ⚖️ Disclaimer: Pearls and Prep is an educational podcast and is not medical advice. All views expressed are exclusively those of NP Z and do not represent — and are not endorsed by — any other entity or organization. These perspectives are offered solely to build conceptual appreciation of psychiatric topics; they are not a substitute for clinical judgment, current clinical guidelines, or primary references. Always use appropriate resources and your own clinical judgment when making decisions about individual patients. Nothing in this episode creates a clinician–patient relationship. This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

💎 Go beyond the episode — study guides, psychopharm deep dives & practice questions: https://www.patreon.com/PearlsandPrep 🎁 Join as a free member to access 50 Pearls from Pearls & Prep — 50 super high-yield pearls to sharpen your practice. 📚 The 100 Psychiatric Interview Tips For Your 1st Eval E-Book is $39.99 in the shop — or get it FREE as a Boss Pearl member: https://www.patreon.com/c/pearlsandprep/shop ⭐ Enjoying the show? Please rate and review Pearls and Prep on Apple Podcasts or Spotify — it really helps! 🌐 PearlsandPrep.com — scan this episode's Street Takes card, read the deep-dive articles, and unlock the full clinical library: https://pearlsandprep.com ✉️ Questions or a case you want covered? Write to NP Z: [email protected] Cariprazine (Vraylar) versus aripiprazole (Abilify): a practical, memorable comparison of two second-generation antipsychotics built around their D2 and D3 receptor differences. This episode covers the FDA indications for each SGA and the clinical reasoning behind choosing one over the other — the why that textbooks skip. Ideal PMHNP boards prep in psychopharmacology, giving new prescribers the clinical confidence to match the right antipsychotic to the right patient. 🎧 Pearls & Prep — new episodes every Tuesday. Hosted by NP Z, Duke-trained Psychiatric Nurse Practitioner. ⚖️ Disclaimer: Pearls and Prep is an educational podcast and is not medical advice. All views expressed are exclusively those of NP Z and do not represent — and are not endorsed by — any other entity or organization. These perspectives are offered solely to build conceptual appreciation of psychiatric topics; they are not a substitute for clinical judgment, current clinical guidelines, or primary references. Always use appropriate resources and your own clinical judgment when making decisions about individual patients. Nothing in this episode creates a clinician–patient relationship. This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

💎 Go beyond the episode — study guides, psychopharm deep dives & practice questions: https://www.patreon.com/PearlsandPrep 🎁 Join as a free member to access 50 Pearls from Pearls & Prep — 50 super high-yield pearls to sharpen your practice. 📚 The 100 Psychiatric Interview Tips For Your 1st Eval E-Book is $39.99 in the shop — or get it FREE as a Boss Pearl member: https://www.patreon.com/c/pearlsandprep/shop ⭐ Enjoying the show? Please rate and review Pearls and Prep on Apple Podcasts or Spotify — it really helps! 🌐 PearlsandPrep.com — scan this episode's Street Takes card, read the deep-dive articles, and unlock the full clinical library: https://pearlsandprep.com ✉️ Questions or a case you want covered? Write to NP Z: [email protected] A patient has panic attacks, avoids driving, and recently witnessed a traumatic accident — PTSD seems obvious, but is it? This DSM-5-TR case study dissects panic disorder versus PTSD, teaching you to distinguish trauma-related avoidance from fear of another panic attack. You will work through the differential diagnosis the way experienced clinicians do, understanding the why behind each criterion. Essential PMHNP boards prep that builds genuine clinical confidence for one of psychiatry's trickiest distinctions. 🎧 Pearls & Prep — new episodes every Tuesday. Hosted by NP Z, Duke-trained Psychiatric Nurse Practitioner. ⚖️ Disclaimer: Pearls and Prep is an educational podcast and is not medical advice. All views expressed are exclusively those of NP Z and do not represent — and are not endorsed by — any other entity or organization. These perspectives are offered solely to build conceptual appreciation of psychiatric topics; they are not a substitute for clinical judgment, current clinical guidelines, or primary references. Always use appropriate resources and your own clinical judgment when making decisions about individual patients. Nothing in this episode creates a clinician–patient relationship. This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy