The Proof with Simon Hill

Live better for longer

Treating Obesity Is Treating the Brain | Dr Elizabeth Kazarian

NOV 3, 2026131 MIN

Description

Elizabeth Kazarian is a physician double board-certified in Family Medicine and Obesity Medicine, practising in Washington DC. She treats obesity for a living, which means she spends as much time on insurance appeals as she does on clinical decisions. Roughly one in ten American adults now reports using a GLP-1 medication, and the public conversation has split between people calling them a shortcut and people calling them a miracle. Elizabeth occupies the far more useful middle ground, and she is candid about where the evidence is strong, where it is thin, and where the real obstacles lie. What We Cover Why treating obesity means treating the brain, and what that does to the willpower argument Why she stopped asking patients to earn medication through failed dieting What happens when people come off these drugs, including the part of the data nobody quotes The insurance and rebate machinery that decides which GLP-1 you are offered BMI, body composition, and working with a tool whose sensitivity is under 50% Menopause, PCOS, and fertility on and off these medications Her case that family medicine is the original longevity medicine This is a clear-eyed look at what obesity medicine actually involves once you get past the injection. If you have found this topic more confusing each year, this conversation should help. You can follow Dr Elizabeth Kazarian's work on Instagram, where she shares evidence-based education on obesity medicine, GLP-1 therapies, and women's cardiometabolic health. If you enjoy the show, please leave a rating and review on Apple Podcasts. It helps new listeners find us. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA 38TERA’s BDR is a clinically dosed gut health supplement for improved digestion, less bloating, better bowel movements and a healthier microbiome. Use code THEPROOF for a discount at checkout. 38Tera ships to the United States, Australia, and New Zealand. Shokz Shokz OpenFit Pro brings Open-Ear Noise Reduction to open-ear listening, so background noise feels farther away while you stay connected to your surroundings. Head to shokz.com/THEPROOF and use code THEPROOF for a long-term discount on all Shokz products, stackable with other official promotions. Gusto Gusto is online payroll and benefits software built for small businesses, handling payroll, tax filing, benefits, and onboarding in one place. Try Gusto today at gusto.com/THEPROOF and get three months free when you run your first payroll. SwimClub SwimClub is a science-backed supplement designed to support male fertility, sperm health, and reproductive wellness. Head to swimclub.co to get $20 off your first order with code THEPROOF. Function Health Make knowing your health part of your holiday plans. Function gives you access to 160+ lab tests for $365 a year—about a dollar a day. Join at functionhealth.com/SIMONHILL and use code SIMON25 for a $25 credit. Function Health ships to 48 U.S. states, excluding Rhode Island, Hawai‘i, and Puerto Rico. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com. IM8 ships to 27 countries including the U.S., Canada, the U.K., Australia, and many regions across Europe, Asia, and South America. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Whoop ships to 56+ international markets, including the US, Canada, most of Europe, Australia, New Zealand, UAE, Singapore, and parts of Asia. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.