In this Resilience Unravelled episode, host Russell interviews Brad Ley in Texas about oxygen and exercise with oxygen therapy (EWOT). Ley explains he turned to oxygen therapy about a decade ago after chronic illness and autoimmune conditions, including psoriasis and autoimmune arthritis, when standard drugs carried serious risks and he developed melanoma. He contrasts EWOT with hyperbaric oxygen therapy, noting hard-shell hyperbaric treatments were recommended to him but were too expensive and time-consuming. Ley describes “inflammaging,” where inflamed blood vessels and swollen capillaries restrict oxygen delivery, pushing cells into anaerobic respiration, lowering energy production and increasing inflammation; he says delivering a high dose of oxygen during exercise can reduce inflammation and help reestablish blood flow in capillaries. He addresses concerns about oxygen and oxidative stress, stating oxygen is also important for detoxification and that research does not show increased oxidative stress from EWOT. Ley outlines the origins of EWOT research from Manfred von Ardenne and explains how oxygen therapy relates to inflammation and hypoxia, comparing it to hydrogen-based approaches. He discusses founding 1000 Roads after building his own system as an engineer and then producing units for patients, with a focus on affordable at-home use and a protocol of about 15 minutes of cardio with a mask, three to five times per week. Ley shares a customer anecdote about osteoarthritis improvement and notes response times vary. The conversation also covers red light therapy, which he says targets mitochondria to increase oxygen demand and pairs with EWOT by boosting oxygen supply then uptake, with claimed benefits including healing, cognitive function, reduced inflammation, skin and collagen support, and recovery. Ley notes the company ships from the US and internationally, with tariffs varying by country, and directs listeners to 1000roads.com and the 1000 Roads HQ YouTube channel for weekly videos on EWOT and red light therapy.00:00 Welcome & meet Brad Ley (Texas)01:04 Why more oxygen can reduce inflammation: ‘inflammaging’, capillaries & hypoxia02:42 Is oxygen ‘rusting’ us? Oxidative stress vs detox benefits03:51 Brad’s autoimmune journey & why he needed a third option05:01 Hyperbaric oxygen vs exercise-with-oxygen: cost, time, practicality06:32 The origins of EWOT: von Ardenne’s research & Brad builds his own device08:32 Oxygen vs hydrogen therapy: how both target inflammation10:01 Oxygen is ‘multimodal’: energy, anti-inflammatory, anti-cancer & detox11:28 At-home EWOT systems: 15 minutes, 3–5x/week, accessible pricing13:11 Can it help osteoarthritis? Early user results & what to expect14:17 Red light therapy explained — mitochondria, oxygen demand & synergy with EWOT17:18 Shipping worldwide, 1000 Roads links & final wrap-upYou can contact us at [email protected]