Mohammad Millwala, CEO of DM Clinical Research and 2025 Christine K. Pierre Impact Award recipient, joins SCRS Honorary President David Vulcano to unpack the most pressing challenges clinical research sites are navigating today.New findings from the 2025 SCRS Global Landscape Survey show protocol complexity topping the list, persistent communication gaps affecting most sites, and ongoing difficulty connecting with patient communities. Together, these leaders offer grounded solutions, including using risk scores to evaluate protocols, tapping existing healthcare infrastructure for recruitment, and rethinking assumptions about research-naive investigators.Listen now for a clear view of what sites are really facing and the ideas gaining momentum across the industry.